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CD104 Antibody (MA5-24024) in WB
Western blot analysis of CD104 in mouse small intestine tissue. Samples were incubated in CD104 monoclonal antibody (Product # MA5-24024) using a dilution of 2 µg/mL followed by a HRP-conjugated Anti-Rat IgG secondary antibody. A specific band was detected for Integrin β4/CD104 at approximately 180 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
MA5-24024
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2A
Class
Monoclonal
Type
Antibody
Clone
308601
Immunogen
CHO-derived recombinant mouse Integrin beta 4/CD104 Asn29-Ser711
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610604
Product Specific Information
This antibody does not cross-react with recombinant mouse Integrin beta 1, beta 2, beta 6, beta 7, or recombinant human Integrin beta 3.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD antigen CD104; CD104; Integrin beta-4
Gene Aliases: AA407042; C230078O20; CD104; Itgb4
UniProt ID: (Mouse) A2A863
Entrez Gene ID: (Mouse) 192897
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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