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Invitrogen
CD104 Monoclonal Antibody (422325), Alexa Fluor™ 488
Product Details
MA5-23641
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2B
Class
Monoclonal
Type
Antibody
Clone
422325
Immunogen
CHO-derived recombinant human Integrin beta 4/CD104 Asn28-Ser710
Conjugate
Excitation/Emission Max
499/520 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
Buffered saline solution with BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609374
Product Specific Information
In Western blots, no cross-reactivity with recombinant human Integrin beta 1, beta 2, beta 3, beta 5, beta 6, beta 8, or recombinant mouse Integrin beta 4 is observed.
Target Information
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD antigen CD104; CD104; CD104 antigen; GP150; Integrin beta-4
Gene Aliases: CD104; GP150; ITGB4
UniProt ID: (Human) P16144
Entrez Gene ID: (Human) 3691
autophagy
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
response to wounding
extracellular matrix organization
hemidesmosome assembly
nail development
skin development
mesodermal cell differentiation
digestive tract development
cell motility
renal system development
amelogenesis
Performance Guarantee
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