Product References
Overexpression of fibroblast growth factor receptor 2 in bone marrow mesenchymal stem cells enhances osteogenesis and promotes critical cranial bone defect regeneration.
Frontiers in cell and developmental biology
Zhou Y,Zhu P,Shen S,Wang Y,Li B,Guo B,Li H
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Sun Jun 04 00:00:00 EDT 2023
Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration.
Stem cell research & therapy
Dushime H,Moreno SG,Linard C,Adrait A,Couté Y,Peltzer J,Messiaen S,Torres C,Bensemmane L,Lewandowski D,Romeo PH,Petit V,Gault N
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Fri Aug 11 00:00:00 EDT 2023
Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration.
Stem cell research & therapy
Dushime H,Moreno SG,Linard C,Adrait A,Couté Y,Peltzer J,Messiaen S,Torres C,Bensemmane L,Lewandowski D,Romeo PH,Petit V,Gault N
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Fri Aug 11 00:00:00 EDT 2023
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nature communications
Linnerbauer M,Beyer T,Nirschl L,Farrenkopf D,Lößlein L,Vandrey O,Peter A,Tsaktanis T,Kebir H,Laplaud D,Oellinger R,Engleitner T,Alvarez JI,Rad R,Korn T,Hemmer B,Quintana FJ,Rothhammer V
12-1051-82 was used in Flow cytometry/Cell sorting to suggest the glial PD-L1/PD-1 axis as a potential therapeutic target for both acute and progressive MS stages.
Sat Sep 09 00:00:00 EDT 2023
Identification of astrocyte regulators by nucleic acid cytometry.
Nature
Clark IC,Wheeler MA,Lee HG,Li Z,Sanmarco LM,Thaploo S,Polonio CM,Shin SW,Scalisi G,Henry AR,Rone JM,Giovannoni F,Charabati M,Akl CF,Aleman DM,Zandee SEJ,Prat A,Douek DC,Boritz EA,Quintana FJ,Abate AR
12-1051-82 was used in Flow cytometry/Cell sorting to develop focused interrogation of cells by nucleic acid detection and sequencing (FIND-seq), a high-throughput microfluidic cytometry method that combines encapsulation of cells in droplets, PCR-based detection of target nucleic acids and droplet sorting to enable in-depth transcriptomic analyses of cells of interest at single-cell resolution.
Wed Feb 01 00:00:00 EST 2023
Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells.
Cell death & disease
Sagar S,Faizan MI,Chaudhary N,Singh V,Singh P,Gheware A,Sharma K,Azmi I,Singh VP,Kharya G,Mabalirajan U,Agrawal A,Ahmad T,Sinha Roy S
12-1051-82 was used in Immunocytochemistry to provide the first comprehensive molecular understanding of impaired mitophagy in obese-derived MSCs and highlight the importance of pharmacological modulation of these cells for therapeutic intervention.
Sat May 13 00:00:00 EDT 2023
Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells.
Cell death & disease
Sagar S,Faizan MI,Chaudhary N,Singh V,Singh P,Gheware A,Sharma K,Azmi I,Singh VP,Kharya G,Mabalirajan U,Agrawal A,Ahmad T,Sinha Roy S
12-1051-82 was used in Immunocytochemistry to provide the first comprehensive molecular understanding of impaired mitophagy in obese-derived MSCs and highlight the importance of pharmacological modulation of these cells for therapeutic intervention.
Sat May 13 00:00:00 EDT 2023
Age-related ultrastructural changes in spheroids of the adipose-derived multipotent mesenchymal stromal cells from ovariectomized mice.
Frontiers in cellular neuroscience
Kyryk V,Tsupykov O,Ustymenko A,Smozhanik E,Govbakh I,Butenko G,Skibo G
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Tue Mar 07 00:00:00 EST 2023
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes.
Nature
Sanmarco LM,Wheeler MA,Gutiérrez-Vázquez C,Polonio CM,Linnerbauer M,Pinho-Ribeiro FA,Li Z,Giovannoni F,Batterman KV,Scalisi G,Zandee SEJ,Heck ES,Alsuwailm M,Rosene DL,Becher B,Chiu IM,Prat A,Quintana FJ
12-1051-82 was used in Flow Cytometry to show that LAMP1+TRAIL+ astrocytes limit CNS inflammation by inducing T cell apoptosis, and that this astrocyte subset is maintained by meningeal IFNγ+ NK cells that are licensed by the microbiome.
Mon Feb 01 00:00:00 EST 2021
Lymph node formation and B cell homeostasis require IKK-α in distinct endothelial cell-derived compartments.
Proceedings of the National Academy of Sciences of the United States of America
McCorkell KA,Jayachandran N,Cully MD,Freund-Brown J,Weinkopff T,Monslow J,Hu Y,Puré E,Freedman BD,Alvarez JI,Cancro MP,May MJ
12-1051-82 was used in Flow cytometry/Cell sorting to reveal that IKK-α in distinct EC-derived compartments is uniquely required to promote B cell homeostasis and LN development, and establish that LEC-intrinsic IKK-α is absolutely essential for LN formation.
Tue Nov 30 00:00:00 EST 2021
PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model.
Journal of cellular physiology
Mardomi A,Limoni SK,Rahbarghazi R,Mohammadi N,Khorashadizadeh M,Ranjbaran H,Nataj HH,Jafari N,Hasani B,Abediankenari S
12-1051-82 was used in Flow Cytometry to verify the potential of PD-L1 overexpression as a preparative strategy for the protection of allogeneic MSCs-derived CLCs against the detrimental alloreaction.© 2021 Wiley Periodicals LLC.
Wed Sep 01 00:00:00 EDT 2021
An Immunometabolic Shift Modulates Cytotoxic Lymphocyte Activation During Melanoma Progression in TRPA1 Channel Null Mice.
Frontiers in oncology
Forni MF,Domínguez-Amorocho OA,de Assis LVM,Kinker GS,Moraes MN,Castrucci AML,Câmara NOS
12-1051-82 was used in Flow Cytometry to demonstrate the role of the TRPA1 channel in the metabolism control of the immune system cells during carcinogenesis.
Fri May 28 00:00:00 EDT 2021
Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors.
Molecular medicine reports
Wei H,Zhou W,Hu G,Shi C
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders.
Journal of extracellular vesicles
Seras-Franzoso J,Díaz-Riascos ZV,Corchero JL,González P,García-Aranda N,Mandaña M,Riera R,Boullosa A,Mancilla S,Grayston A,Moltó-Abad M,Garcia-Fruitós E,Mendoza R,Pintos-Morell G,Albertazzi L,Rosell A,Casas J,Villaverde A,Schwartz S,Abasolo I
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
12-1051-82 was used in Flow cytometry/Cell sorting to unveil a new role of MSCs-Exo containing miR-223 in the treatment of acute graft-versus-host disease (aGvHD).
Fri Feb 26 00:00:00 EST 2021
MAFG-driven astrocytes promote CNS inflammation.
Nature
Wheeler MA,Clark IC,Tjon EC,Li Z,Zandee SEJ,Couturier CP,Watson BR,Scalisi G,Alkwai S,Rothhammer V,Rotem A,Heyman JA,Thaploo S,Sanmarco LM,Ragoussis J,Weitz DA,Petrecca K,Moffitt JR,Becher B,Antel JP,Prat A,Quintana FJ
12-1051-82 was used in Flow Cytometry to identify candidate therapeutic targets in multiple sclerosis.
Sat Feb 01 00:00:00 EST 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
12-1051 was used in Flow cytometry/Cell sorting to investigate the dose-dependent effect of HMGB-1 on tendon cells and tissues.
Sun Apr 17 00:00:00 EDT 2022
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
12-1051 was used in Flow cytometry/Cell sorting to investigate the dose-dependent effect of HMGB-1 on tendon cells and tissues.
Sun Apr 17 00:00:00 EDT 2022
Icariin Promote Stem Cells Regeneration and Repair Acinar Cells in L-arginine / Radiation -Inducing Chronic Pancreatitis in Rats.
Dose-response : a publication of International Hormesis Society
Moustafa EM,Moawed FSM,Abdel-Hamid GR
12-1051-82 was used in Flow Cytometry to evaluate the ability of bone marrow-based mesenchymal stem cell combined with Icariin to restore and regenerate acinar cells in the pancreas of rats suffering chronic pancreatitis.
Mon Apr 18 00:00:00 EDT 2022
IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway.
Stem cell research & therapy
Lin M,Liu X,Zheng H,Huang X,Wu Y,Huang A,Zhu H,Hu Y,Mai W,Huang Y
12-1051 was used in Flow cytometry/Cell sorting to investigate whether overexpressing IGF-1 could enhance the bone marrow mesenchymal stem cell viability, migration, anti-apoptosis, and protective effects of cardiomyocytes, and explore the underlying mechanisms' focus on the role of the AKT/secreted frizzled-related protein 2/β-catenin pathway.
Thu Jan 09 00:00:00 EST 2020
IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway.
Stem cell research & therapy
Lin M,Liu X,Zheng H,Huang X,Wu Y,Huang A,Zhu H,Hu Y,Mai W,Huang Y
12-1051 was used in Flow cytometry/Cell sorting to investigate whether overexpressing IGF-1 could enhance the bone marrow mesenchymal stem cell viability, migration, anti-apoptosis, and protective effects of cardiomyocytes, and explore the underlying mechanisms' focus on the role of the AKT/secreted frizzled-related protein 2/β-catenin pathway.
Thu Jan 09 00:00:00 EST 2020
Nestin-GFP transgene labels skeletal progenitors in the periosteum.
Bone
Tournaire G,Stegen S,Giacomini G,Stockmans I,Moermans K,Carmeliet G,van Gastel N
12-1051-82 was used in Flow Cytometry to show that in adult mice, Nes-GFP cells are present in the periosteum and localize closely to blood vessels, but periosteal Nes-GFP cells express SSC and progenitor markers differently compared to Nes-GFP cells in the bone marrow.
Wed Apr 01 00:00:00 EDT 2020
IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b.
Cell death & disease
Yang R,Huang H,Cui S,Zhou Y,Zhang T,Zhou Y
12-1051-82 was used in Flow Cytometry to investigate the potential anti-inflammatory effects of bone marrow mesenchymal stem cell-derived exosomes.
Thu Jul 30 00:00:00 EDT 2020
Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS.
Cell
Chao CC,Gutiérrez-Vázquez C,Rothhammer V,Mayo L,Wheeler MA,Tjon EC,Zandee SEJ,Blain M,de Lima KA,Takenaka MC,Avila-Pacheco J,Hewson P,Liu L,Sanmarco LM,Borucki DM,Lipof GZ,Trauger SA,Clish CB,Antel JP,Prat A,Quintana FJ
12-1051-82 was used in Flow Cytometry to define a novel immunometabolic mechanism that drives pro-inflammatory astrocyte activities.
Thu Dec 12 00:00:00 EST 2019
Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.
The Journal of clinical investigation
Stivala S,Codilupi T,Brkic S,Baerenwaldt A,Ghosh N,Hao-Shen H,Dirnhofer S,Dettmer MS,Simillion C,Kaufmann BA,Chiu S,Keller M,Kleppe M,Hilpert M,Buser AS,Passweg JR,Radimerski T,Skoda RC,Levine RL,Meyer SC
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Mon Mar 04 00:00:00 EST 2019
Leptin Induces Proadipogenic and Proinflammatory Signaling in Adipocytes.
Frontiers in endocrinology
Palhinha L,Liechocki S,Hottz ED,Pereira JADS,de Almeida CJ,Moraes-Vieira PMM,Bozza PT,Maya-Monteiro CM
12-1051-82 was used in Flow Cytometry to contribute to the understanding of the local signaling of leptin in precursor and mature adipose cells.
Mon Jan 13 00:00:00 EST 2020
Leptin Induces Proadipogenic and Proinflammatory Signaling in Adipocytes.
Frontiers in endocrinology
Palhinha L,Liechocki S,Hottz ED,Pereira JADS,de Almeida CJ,Moraes-Vieira PMM,Bozza PT,Maya-Monteiro CM
12-1051-82 was used in Flow Cytometry to contribute to the understanding of the local signaling of leptin in precursor and mature adipose cells.
Mon Jan 13 00:00:00 EST 2020
LPS‑induced upregulation of the TLR4 signaling pathway inhibits osteogenic differentiation of human periodontal ligament stem cells under inflammatory conditions.
International journal of molecular medicine
Yu B,Li Q,Zhou M
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
LPS‑induced upregulation of the TLR4 signaling pathway inhibits osteogenic differentiation of human periodontal ligament stem cells under inflammatory conditions.
International journal of molecular medicine
Yu B,Li Q,Zhou M
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
Isolation and functional assessment of mouse skeletal stem cell lineage.
Nature protocols
Gulati GS,Murphy MP,Marecic O,Lopez M,Brewer RE,Koepke LS,Manjunath A,Ransom RC,Salhotra A,Weissman IL,Longaker MT,Chan CKF
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
12-1051 was used in Flow cytometry/Cell sorting to provide molecular insights into the role of Rho GTPases in TGFβ signalling and understanding of mesenchymal stem cells in fibriosis.
Fri Jun 15 00:00:00 EDT 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
12-1051 was used in Flow cytometry/Cell sorting to provide molecular insights into the role of Rho GTPases in TGFβ signalling and understanding of mesenchymal stem cells in fibriosis.
Fri Jun 15 00:00:00 EDT 2018
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.
Nature communications
Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B
12-1051 was used in Flow cytometry/Cell sorting to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.
Tue May 15 00:00:00 EDT 2018
Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.
Nature communications
Yang R,Yu T,Kou X,Gao X,Chen C,Liu D,Zhou Y,Shi S
12-1051 was used in Flow cytometry/Cell sorting to indicate that Tet1 and Tet2 play a role in maintaining mesenchymal stem cell and bone homeostasis through demethylation of P2rX7.
Fri Jun 01 00:00:00 EDT 2018
Hematopoietic Stem Cells but Not Multipotent Progenitors Drive Erythropoiesis during Chronic Erythroid Stress in EPO Transgenic Mice.
Stem cell reports
Singh RP,Grinenko T,Ramasz B,Franke K,Lesche M,Dahl A,Gassmann M,Chavakis T,Henry I,Wielockx B
12-1051 was used in Mass cytometry to compare and characterise the cellular profiles and signatures of haematopoietic stem cells and multipotent progenitors during chronic erythroid stress.
Tue Jun 05 00:00:00 EDT 2018
Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation.
Cell death & disease
Ding Y,Liang X,Zhang Y,Yi L,Shum HC,Chen Q,Chan BP,Fan H,Liu Z,Tergaonkar V,Qi Z,Tse HF,Lian Q
12-1051 was used in Flow cytometry/Cell sorting to indicate that Rap1 is essential to maintain the immunomodulatory function of MSCs.
Wed Mar 07 00:00:00 EST 2018
miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells.
Aging cell
Onodera Y,Teramura T,Takehara T,Obora K,Mori T,Fukuda K
12-1051 was used in Flow cytometry/Cell sorting to identify miR-155 as an inducer of reactive oxygen species generation in mesenchymal stem cells.
Fri Dec 01 00:00:00 EST 2017
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.
Stem cell reports
Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
Equine Dental Pulp Connective Tissue Particles Reduced Lameness in Horses in a Controlled Clinical Trial.
Frontiers in veterinary science
Bertone AL,Reisbig NA,Kilborne AH,Kaido M,Salmanzadeh N,Lovasz R,Sizemore JL,Scheuermann L,Kopp RJ,Zekas LJ,Brokken MT
12-1051 was used in Flow cytometry/Cell sorting to assess if injection of allogeneic dental pulp tissue particles improves lameness in horses with naturally occurring osteoarthritis or soft tissue injury.
Sun Nov 12 00:00:00 EST 2023
Identification of blood vascular endothelial stem cells by the expression of protein C receptor.
Cell research
Yu QC,Song W,Wang D,Zeng YA
12-1051 was used in Flow cytometry/Cell sorting to investigate the existence and identity of vascular endothelial stem cells, showing that these cells express the protein C receptor.
Sat Oct 01 00:00:00 EDT 2016
Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.
Cancer cell
Phoenix TN,Patmore DM,Boop S,Boulos N,Jacus MO,Patel YT,Roussel MF,Finkelstein D,Goumnerova L,Perreault S,Wadhwa E,Cho YJ,Stewart CF,Gilbertson RJ
12-1051 was used in Flow cytometry/Cell sorting to demonstrate the biological basis of WNT-medulloblastoma treatment sensitivity: medulloblastoma genotype dictates tumour vessel phenotype, partially explaining disparate prognoses among subtypes.
Mon Apr 11 00:00:00 EDT 2016
Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells.
Leukemia
Wen S,Dooner M,Cheng Y,Papa E,Del Tatto M,Pereira M,Deng Y,Goldberg L,Aliotta J,Chatterjee D,Stewart C,Carpanetto A,Collino F,Bruno S,Camussi G,Quesenberry P
12-1051 was used in Flow cytometry/Cell sorting to evaluate the capacity of mesenchymal stromal cell-derived extracellular vesicles to rescue murine marrow hematopoietic cells damage following exposure to radiation, showing that damage could be reversed using both murine and human MSC-EVs.
Tue Nov 01 00:00:00 EDT 2016
Endothelial cell survival during angiogenesis requires the pro-survival protein MCL1.
Cell death and differentiation
Watson EC,Whitehead L,Adams RH,Dewson G,Coultas L
12-1051 was used in Flow cytometry/Cell sorting to investigate the in vivo role of myeloid cell leukaemia 1 (MCL1) in endothelial cell survival during angiogenesis.
Mon Aug 01 00:00:00 EDT 2016
A New Method to Stabilize C-Kit Expression in Reparative Cardiac Mesenchymal Cells.
Frontiers in cell and developmental biology
Wysoczynski M,Dassanayaka S,Zafir A,Ghafghazi S,Long BW,Noble C,DeMartino AM,Brittian KR,Bolli R,Jones SP
12-1051 was used in Flow cytometry/Cell sorting to investigate a new method for c-kit expressing cell isolation and stabilisation in reparative cardiac mesenchymal cells.
Thu Aug 18 00:00:00 EDT 2016
Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response.
PLoS genetics
Ojeda-Fernández L,Recio-Poveda L,Aristorena M,Lastres P,Blanco FJ,Sanz-Rodríguez F,Gallardo-Vara E,de las Casas-Engel M,Corbí Á,Arthur HM,Bernabeu C,Botella LM
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
A mouse model for a partially inactive obesity-associated human MC3R variant.
Nature communications
Lee B,Koo J,Yun Jun J,Gavrilova O,Lee Y,Seo AY,Taylor-Douglas DC,Adler-Wailes DC,Chen F,Gardner R,Koutzoumis D,Sherafat Kazemzadeh R,Roberson RB,Yanovski JA
12-1051 was used in Flow cytometry/Cell sorting to confirm the importance of MC3R signalling in human metabolism, and suggest a novel role for MC3R in adipose tissue development.
Thu Jan 28 00:00:00 EST 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.
Blood
Kosoff RE,Aslan JE,Kostyak JC,Dulaimi E,Chow HY,Prudnikova TY,Radu M,Kunapuli SP,McCarty OJ,Chernoff J
12-1051 was used in Flow cytometry/Cell sorting to identify a novel role for Pak2 as an important regulator of megakaryopoiesis, polyploidization and cytoskeletal mechanics in developing megakaryocytes.
Thu May 07 00:00:00 EDT 2015
Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation.
American journal of physiology. Lung cellular and molecular physiology
Woods SJ,Waite AA,O'Dea KP,Halford P,Takata M,Wilson MR
12-1051 was used in Flow cytometry/Cell sorting to identify the profile of in vivo lung cellular activation that occurs during the initiation of VILI.
Fri May 01 00:00:00 EDT 2015
Generation of embryonic stem cells from mouse adipose-tissue derived cells via somatic cell nuclear transfer.
Cell cycle (Georgetown, Tex.)
Qin Y,Qin J,Zhou C,Li J,Gao WQ
12-1051 was used in Flow cytometry/Cell sorting to demonstrates that ESCs can be generated from the adipose tissue by somatic cell nuclear transfer (SCNT) and suggests that ADCs can be a new donor-cell type for potential therapeutic cloning.
Tue Jan 26 00:00:00 EST 2016
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
12-1051 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis.
Biology open
Nasrallah R,Knezevic K,Thai T,Thomas SR,Göttgens B,Lacaud G,Kouskoff V,Pimanda JE
12105182 was used in flow cytometry to investigate the role of endoglin in the development of hematopoietic cells.
Fri May 15 00:00:00 EDT 2015
Alveolar macrophage phenotype expression in airway-instilled bone marrow cells in mice.
SpringerPlus
Okui M,Goto T,Asakura K,Kamiyama I,Ohtsuka T
12-1051 was used in Flow cytometry/Cell sorting to study how intratracheally instilled bone marrow cells adapt to the surrounding microenvironment, directly differentiating into alveolar macrophages, and remain in the alveolar space for at least 3 months.
Mon Dec 21 00:00:00 EST 2015
Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing.
EMBO molecular medicine
Coutelle O,Hornig-Do HT,Witt A,Andree M,Schiffmann LM,Piekarek M,Brinkmann K,Seeger JM,Liwschitz M,Miwa S,Hallek M,Krönke M,Trifunovic A,Eming SA,Wiesner RJ,Hacker UT,Kashkar H
12-1051 was used in Immunohistochemistry to demonstrate a novel therapy to control pathological neoangiogenesis while sparing normal vasculature.
Thu May 01 00:00:00 EDT 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Characteristic of c-Kit+ progenitor cells in explanted human hearts.
Clinical research in cardiology : official journal of the German Cardiac Society
Matuszczak S,Czapla J,Jarosz-Biej M,Wiśniewska E,Cichoń T,Smolarczyk R,Kobusińska M,Gajda K,Wilczek P,Sliwka J,Zembala M,Zembala M,Szala S
12-1051 was used in Flow cytometry/Cell sorting to determine the presence of self-renewing, multipotent, and clonogenic progenitor cells within human myocardium.
Mon Sep 01 00:00:00 EDT 2014
Modulation of the early inflammatory microenvironment in the alkali-burned eye by systemically administered interferon-γ-treated mesenchymal stromal cells.
Stem cells and development
Javorkova E,Trosan P,Zajicova A,Krulova M,Hajkova M,Holan V
12-1051 was used in Flow cytometry/Cell sorting to investigate the effects of systemically administered bone-marrow-derived mesenchymal stromal cells on the early acute phase of inflammation in the alkali-burned eye.
Wed Oct 15 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
12-1051 was used in Flow cytometry/Cell sorting to demonstrate the therapeutic effects of AFSCs and suggest the use of AFSCs for treating infertility and POF.
Thu May 28 00:00:00 EDT 2015
Porous silk scaffolds for delivery of growth factors and stem cells to enhance bone regeneration.
PloS one
Zhang W,Zhu C,Ye D,Xu L,Zhang X,Wu Q,Zhang X,Kaplan DL,Jiang X
12-1051-82 was used in Flow cytometry/Cell sorting to evaluate the influence of porous silk scaffolds on rat bone marrow stem cells.
Mon Mar 28 00:00:00 EDT 2016
Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity.
BioMed research international
Roehrich ME,Spicher A,Milano G,Vassalli G
12-1051 was used in Flow cytometry/Cell sorting to investigate the presence of cardiac-resident progenitor cells with high aldehyde dehydrogenase activity isolated from mouse hearts.
Tue Sep 03 00:00:00 EDT 2013
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
Blood
Capitano ML,Nemeth MJ,Mace TA,Salisbury-Ruf C,Segal BH,McCarthy PL,Repasky EA
12-1051 was used in Flow cytometry/Cell sorting to study the factors limiting the immune system recovery process after chemo- and radiotherapy.
Thu Sep 27 00:00:00 EDT 2012
The endothelial antigen ESAM monitors hematopoietic stem cell status between quiescence and self-renewal.
Journal of immunology (Baltimore, Md. : 1950)
Sudo T,Yokota T,Oritani K,Satoh Y,Sugiyama T,Ishida T,Shibayama H,Ezoe S,Fujita N,Tanaka H,Maeda T,Nagasawa T,Kanakura Y
12-1051 was used in Flow cytometry/Cell sorting to demonstrate that the intensity of ESAM expression is useful to trace activated HSCs.
Sun Jul 01 00:00:00 EDT 2012
The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population.
Stem cells and development
Svobodova E,Krulova M,Zajicova A,Pokorna K,Prochazkova J,Trosan P,Holan V
12-1051 was used in Flow cytometry/Cell sorting to demonstrate the importance of MSCs in regulating differentiation and development of Th17 cells from naive CD4+CD25- precursors.
Tue Apr 10 00:00:00 EDT 2012
Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells.
PloS one
Cheng CC,Lian WS,Hsiao FS,Liu IH,Lin SP,Lee YH,Chang CC,Xiao GY,Huang HY,Cheng CF,Cheng WT,Wu SC
Published figure using CD105 (Endoglin) monoclonal antibody (Product # 12-1051-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2012
Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells.
PloS one
Rosu-Myles M,She YM,Fair J,Muradia G,Mehic J,Menendez P,Prasad SS,Cyr TD
12-1051 was used in Flow cytometry/Cell sorting to provide evidence of heterogeneity among bone marrow stromal cells and identify potential candidate proteins for quantifying MSCs in vitro.
Thu Dec 13 00:00:00 EST 2012
Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair.
Cell stem cell
Loffredo FS,Steinhauser ML,Gannon J,Lee RT
12-1051 was used in Flow cytometry/Cell sorting to stimulate endogenous cardiomyocyte progenitors and promote cardiac repair as part of bone marrow-derived cell therapy.
Fri Apr 08 00:00:00 EDT 2011
Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-β1 inhibition.
Future oncology (London, England)
Yan A,Avraham T,Zampell JC,Haviv YS,Weitman E,Mehrara BJ
12-1051 was used in Flow cytometry/Cell sorting to determine whether ASCs can be used in lymphatic tissue-engineering by altering the balance between lymphangiogenic cytokines.
Thu Dec 01 00:00:00 EST 2011
Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-β1 inhibition.
Future oncology (London, England)
Yan A,Avraham T,Zampell JC,Haviv YS,Weitman E,Mehrara BJ
12-1051 was used in Flow cytometry/Cell sorting to determine whether ASCs can be used in lymphatic tissue-engineering by altering the balance between lymphangiogenic cytokines.
Thu Dec 01 00:00:00 EST 2011
Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.
The Journal of biological chemistry
Xu D,Fuster MM,Lawrence R,Esko JD
12-1051 was used in Flow cytometry/Cell sorting to demonstrate how VEGF-induced vascular hyper-permeability depends on endothelial heparan sulfate.
Fri Jan 07 00:00:00 EST 2011
Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos.
Development (Cambridge, England)
Yokomizo T,Dzierzak E
12-1051 was used in Flow cytometry/Cell sorting to devise a method to make transparent whole mouse embryos for the observation of hematopoietic clusters.
Mon Nov 01 00:00:00 EDT 2010
The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice.
Blood
Yokota T,Oritani K,Butz S,Kokame K,Kincade PW,Miyata T,Vestweber D,Kanakura Y
12-1051 was used in Flow cytometry/Cell sorting to study hematopoietic stem cell (HSC) characteristics for improved understanding of their development and stage-related functions, showing that the endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice.
Thu Mar 26 00:00:00 EDT 2009
A subpopulation of mesenchymal stromal cells with high osteogenic potential.
Journal of cellular and molecular medicine
Liu H,Toh WS,Lu K,MacAry PA,Kemeny DM,Cao T
12-1051 was used in Flow cytometry/Cell sorting to identify and isolate a sub-population of murine mesenchymal stem cells at an early passage number with high osteogenic potential.
Sat Aug 01 00:00:00 EDT 2009
Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction.
Journal of molecular and cellular cardiology
Zuba-Surma EK,Kucia M,Dawn B,Guo Y,Ratajczak MZ,Bolli R
12-1051 was used in Flow cytometry/Cell sorting to demonstrate that Oct-4+ pluripotent stem cells (VSELs) are mobilized from the bone marrow into the peripheral blood after acute myocardial infarction.
Thu May 01 00:00:00 EDT 2008
Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure.
Bone
Wu X,Yu G,Parks H,Hebert T,Goh BC,Dietrich MA,Pelled G,Izadpanah R,Gazit D,Bunnell BA,Gimble JM
Thu May 01 00:00:00 EDT 2008
Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature.
Clinical cancer research : an official journal of the American Association for Cancer Research
Korpanty G,Carbon JG,Grayburn PA,Fleming JB,Brekken RA
Mon Jan 01 00:00:00 EST 2007
Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice.
Journal of immunology (Baltimore, Md. : 1950)
Onoe T,Ohdan H,Tokita D,Shishida M,Tanaka Y,Hara H,Zhou W,Ishiyama K,Mitsuta H,Ide K,Asahara T
Fri Jul 01 00:00:00 EDT 2005