Invitrogen

CD105 (Endoglin) Monoclonal Antibody (MJ7/18), eBioscience™

23 Published Figures

42 References

View all (127) CD105 (Endoglin) antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (23)

CD105 (Endoglin) Antibody in Flow Cytometry (Flow)

FIGURE: 1 / 24

CD105 (Endoglin) Antibody (14-1051-82) in Flow

Staining of bEnd-3 cell line with 0.25 µg of Rat IgG2a kappa Isotype Control Purified (Product # 14-4321-82) (open histogram) or 0.25 µg of Anti-Mouse CD105 (Endoglin) Purified (filled histogram) followed by Anti-Rat IgG FITC (Product # 11-4811-85). Total viable cells were used for analysis.

CD105 (Endoglin) Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

CD105 (Endoglin) Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

CD105 (Endoglin) Antibody in Immunohistochemistry (IHC)

CD105 (Endoglin) Antibody in Flow Cytometry, ELISA (Flow, ELISA)

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Product Details

14-1051-82

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 10 publications 10 publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.5 µg/test

View 23 publications 23 publications

ELISA (ELISA)

View 1 publication 1 publication

Immunoprecipitation (IP)

Assay-Dependent

Product Specifications

Species Reactivity

Mouse

Published species

Mouse, Rat

Host/Isotype

Rat / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

MJ7/18

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_467414

Product Specific Information

Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.

Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistochemical staining of frozen tissue sections.

Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells or mouse splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Purity: Greater than 90%, as determined by SDS-PAGE.

Aggregation: Less than 10%, as determined by HPLC.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Overexpression of fibroblast growth factor receptor 2 in bone marrow mesenchymal stem cells enhances osteogenesis and promotes critical cranial bone defect regeneration.

Frontiers in cell and developmental biology

Zhou Y,Zhu P,Shen S,Wang Y,Li B,Guo B,Li H

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Sun Jun 04 00:00:00 EDT 2023

Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration.

Stem cell research & therapy

Dushime H,Moreno SG,Linard C,Adrait A,Couté Y,Peltzer J,Messiaen S,Torres C,Bensemmane L,Lewandowski D,Romeo PH,Petit V,Gault N

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Fri Aug 11 00:00:00 EDT 2023

Frontiers in cellular neuroscience

Kyryk V,Tsupykov O,Ustymenko A,Smozhanik E,Govbakh I,Butenko G,Skibo G

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Tue Mar 07 00:00:00 EST 2023

Hypoxia pretreatment enhances the therapeutic potential of mesenchymal stem cells (BMSCs) on ozone-induced lung injury in rats.

Cell and tissue research

Abdelrahman SA,Abdelrahman AA,Samy W,Dessouky AA,Ahmed SM

14-1051-82 was used in Immunohistochemistry to demonstrate that hypoxia pretreatment represents a valuable intervention to enhance the effects of MSCs on chronic lung injury.

Mon Aug 01 00:00:00 EDT 2022

Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors.

Molecular medicine reports

Wei H,Zhou W,Hu G,Shi C

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders.

Journal of extracellular vesicles

Seras-Franzoso J,Díaz-Riascos ZV,Corchero JL,González P,García-Aranda N,Mandaña M,Riera R,Boullosa A,Mancilla S,Grayston A,Moltó-Abad M,Garcia-Fruitós E,Mendoza R,Pintos-Morell G,Albertazzi L,Rosell A,Casas J,Villaverde A,Schwartz S,Abasolo I

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.

Therapeutic advances in chronic disease

Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Sun Apr 17 00:00:00 EDT 2022

Live-animal imaging of native haematopoietic stem and progenitor cells.

Nature

Christodoulou C,Spencer JA,Yeh SA,Turcotte R,Kokkaliaris KD,Panero R,Ramos A,Guo G,Seyedhassantehrani N,Esipova TV,Vinogradov SA,Rudzinskas S,Zhang Y,Perkins AS,Orkin SH,Calogero RA,Schroeder T,Lin CP,Camargo FD

14-1051-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot to point to previously unknown heterogeneity within the bone marrow microenvironment, imposed by the stages of bone turnover.

Sat Feb 01 00:00:00 EST 2020

Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.

The Journal of clinical investigation

Stivala S,Codilupi T,Brkic S,Baerenwaldt A,Ghosh N,Hao-Shen H,Dirnhofer S,Dettmer MS,Simillion C,Kaufmann BA,Chiu S,Keller M,Kleppe M,Hilpert M,Buser AS,Passweg JR,Radimerski T,Skoda RC,Levine RL,Meyer SC

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Mon Mar 04 00:00:00 EST 2019

LPS‑induced upregulation of the TLR4 signaling pathway inhibits osteogenic differentiation of human periodontal ligament stem cells under inflammatory conditions.

International journal of molecular medicine

Yu B,Li Q,Zhou M

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.

Nature communications

Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Fri Jun 28 00:00:00 EDT 2019

Isolation and functional assessment of mouse skeletal stem cell lineage.

Nature protocols

Gulati GS,Murphy MP,Marecic O,Lopez M,Brewer RE,Koepke LS,Manjunath A,Ransom RC,Salhotra A,Weissman IL,Longaker MT,Chan CKF

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Tissue engineering. Part C, Methods

Blackshear CP,Borrelli MR,Shen EZ,Ransom RC,Chung NN,Vistnes SM,Irizarry D,Nazerali R,Momeni A,Longaker MT,Wan DC

14-1051 was used in Immunohistochemistry-immunofluorescence to determine whether murine adipose tissue can be used as an accurate comparative model of human disease, by comparing its architecture again human abdominal and gluteofemoral adipose tissue.

Mon Oct 01 00:00:00 EDT 2018

Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Tissue engineering. Part C, Methods

Blackshear CP,Borrelli MR,Shen EZ,Ransom RC,Chung NN,Vistnes SM,Irizarry D,Nazerali R,Momeni A,Longaker MT,Wan DC

Mon Oct 01 00:00:00 EDT 2018

Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Tissue engineering. Part C, Methods

Blackshear CP,Borrelli MR,Shen EZ,Ransom RC,Chung NN,Vistnes SM,Irizarry D,Nazerali R,Momeni A,Longaker MT,Wan DC

Mon Oct 01 00:00:00 EDT 2018

Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Tissue engineering. Part C, Methods

Blackshear CP,Borrelli MR,Shen EZ,Ransom RC,Chung NN,Vistnes SM,Irizarry D,Nazerali R,Momeni A,Longaker MT,Wan DC

Mon Oct 01 00:00:00 EDT 2018

RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.

The Journal of biological chemistry

Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Fri Jun 15 00:00:00 EDT 2018

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.

Nature cell biology

Jin Y,Muhl L,Burmakin M,Wang Y,Duchez AC,Betsholtz C,Arthur HM,Jakobsson L

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Immunofluorescence

Thu Jun 01 00:00:00 EDT 2017

Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.

Stem cell reports

Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM

14-1051 was used in Flow cytometry/Cell sorting to demonstrate that the pro-angiogenic properties of the cardiosphere-derived-cell secretome are endoglin dependent.

Tue May 09 00:00:00 EDT 2017

Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.

Stem cell reports

Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM

14-1051 was used in Flow cytometry/Cell sorting to demonstrate that the pro-angiogenic properties of the cardiosphere-derived-cell secretome are endoglin dependent.

Tue May 09 00:00:00 EDT 2017

Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response.

PLoS genetics

Ojeda-Fernández L,Recio-Poveda L,Aristorena M,Lastres P,Blanco FJ,Sanz-Rodríguez F,Gallardo-Vara E,de las Casas-Engel M,Corbí Á,Arthur HM,Bernabeu C,Botella LM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in ELISA

Tue Mar 01 00:00:00 EST 2016

Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response.

PLoS genetics

Ojeda-Fernández L,Recio-Poveda L,Aristorena M,Lastres P,Blanco FJ,Sanz-Rodríguez F,Gallardo-Vara E,de las Casas-Engel M,Corbí Á,Arthur HM,Bernabeu C,Botella LM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in ELISA

Tue Mar 01 00:00:00 EST 2016

Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response.

PLoS genetics

Ojeda-Fernández L,Recio-Poveda L,Aristorena M,Lastres P,Blanco FJ,Sanz-Rodríguez F,Gallardo-Vara E,de las Casas-Engel M,Corbí Á,Arthur HM,Bernabeu C,Botella LM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in ELISA

Tue Mar 01 00:00:00 EST 2016

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

Nature medicine

Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors.

Clinical & experimental metastasis

Moen I,Gebre M,Alonso-Camino V,Chen D,Epstein D,McDonald DM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Immunofluorescence

Tue Dec 01 00:00:00 EST 2015

Tie1 is required for lymphatic valve and collecting vessel development.

Developmental biology

Qu X,Zhou B,Scott Baldwin H

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Immunofluorescence

Sun Mar 01 00:00:00 EST 2015

Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.

Journal of biomedical science

Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Thu Mar 13 00:00:00 EDT 2014

Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice.

Nature communications

Leibowitz BJ,Wei L,Zhang L,Ping X,Epperly M,Greenberger J,Cheng T,Yu J

14-1051 was used in Immunohistochemistry to separate the effects of radiation on the intestinal epithelium from those on the BM and endothelial cells in dose-dependent acute radiation toxicity.

Tue Mar 18 00:00:00 EDT 2014

Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection.

Cell host & microbe

Jordan S,Ruzsics Z,Mitrović M,Baranek T,Arapović J,Krmpotić A,Vivier E,Dalod M,Jonjić S,Dölken L,Koszinowski UH

14-1051 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms of extramedullary hematopoiesis.

Wed May 15 00:00:00 EDT 2013

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.

The Journal of experimental medicine

Anderberg C,Cunha SI,Zhai Z,Cortez E,Pardali E,Johnson JR,Franco M,Páez-Ribes M,Cordiner R,Fuxe J,Johansson BR,Goumans MJ,Casanovas O,ten Dijke P,Arthur HM,Pietras K

14-1051 was used in Immunohistochemistry on frozen tissues to investigate the long-term consequences of genetically impaired angiogenesis.

Mon Mar 11 00:00:00 EDT 2013

Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma.

Cancer research

Song K,Herzog BH,Sheng M,Fu J,McDaniel JM,Chen H,Ruan J,Xia L

14-1051 was used in Immunohistochemistry to determine whether lymphatic vessels contribute to the growth and spread of lymphomas.

Sun Dec 15 00:00:00 EST 2013

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation.

eLife

Kerenyi MA,Shao Z,Hsu YJ,Guo G,Luc S,O'Brien K,Fujiwara Y,Peng C,Nguyen M,Orkin SH

14-1051 was used in Flow cytometry/Cell sorting to study how Lsd1-mediated concurrent repression of enhancer and promoter activity of stem and progenitor cell genes is a pivotal epigenetic mechanism required for proper hematopoietic maturation.

Tue Jun 18 00:00:00 EDT 2013

Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells.

PloS one

Cheng CC,Lian WS,Hsiao FS,Liu IH,Lin SP,Lee YH,Chang CC,Xiao GY,Huang HY,Cheng CF,Cheng WT,Wu SC

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Fri Sep 07 00:00:00 EDT 2012

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.

Blood

Kharazi S,Mead AJ,Mansour A,Hultquist A,Böiers C,Luc S,Buza-Vidas N,Ma Z,Ferry H,Atkinson D,Reckzeh K,Masson K,Cammenga J,Rönnstrand L,Arai F,Suda T,Nerlov C,Sitnicka E,Jacobsen SE

14-1051 was used in Flow cytometry/Cell sorting to study the relationship between gene dosage and FLT3 production.

Thu Sep 29 00:00:00 EDT 2011

Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-β1 inhibition.

Future oncology (London, England)

Yan A,Avraham T,Zampell JC,Haviv YS,Weitman E,Mehrara BJ

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2011

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos.

Development (Cambridge, England)

Yokomizo T,Dzierzak E

14-1051 was used in Flow cytometry/Cell sorting to devise a method to make transparent whole mouse embryos for the observation of hematopoietic clusters.

Mon Nov 01 00:00:00 EDT 2010

Rapid remodeling of airway vascular architecture at birth.

Developmental dynamics : an official publication of the American Association of Anatomists

Ni A,Lashnits E,Yao LC,Baluk P,McDonald DM

14-1051 was used in Immunohistochemistry to determine whether the airway vasculature changes during the perinatal period, and when the typical adult pattern develops.

Wed Sep 01 00:00:00 EDT 2010

Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.

Laboratory investigation; a journal of technical methods and pathology

Mahmoud M,Borthwick GM,Hislop AA,Arthur HM

14-1051 was used in Immunohistochemistry to elucidate the potential link between endoglin (ENG) or activin receptor-like kinase 1 (ACVRL1) deficiency and arteriovenous malformations (AVMs) formation in hereditary haemorrhagic telangiectasia.

Thu Jan 01 00:00:00 EST 2009

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice.

The Journal of clinical investigation

Fu J,Gerhardt H,McDaniel JM,Xia B,Liu X,Ivanciu L,Ny A,Hermans K,Silasi-Mansat R,McGee S,Nye E,Ju T,Ramirez MI,Carmeliet P,Cummings RD,Lupu F,Xia L

14-1051 was used in Immunohistochemistry to investigate the roles of mucin-type-O-glycans in vascular endothelial cells.

Sat Nov 01 00:00:00 EDT 2008

Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure.

Bone

Wu X,Yu G,Parks H,Hebert T,Goh BC,Dietrich MA,Pelled G,Izadpanah R,Gazit D,Bunnell BA,Gimble JM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 14-1051-82) in Flow Cytometry

Thu May 01 00:00:00 EDT 2008

Deciphering developmental stages of adult myelopoiesis.

Cell cycle (Georgetown, Tex.)

Pronk CJ,Attema J,Rossi DJ,Sigvardsson M,Bryder D

14-1051 was used in Flow cytometry/Cell sorting to provide additional characterization of these cellular subsets to further refine their developmental potential.

Sat Mar 15 00:00:00 EDT 2008

Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature.

Clinical cancer research : an official journal of the American Association for Cancer Research

Korpanty G,Carbon JG,Grayburn PA,Fleming JB,Brekken RA

Mon Jan 01 00:00:00 EST 2007

A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.

Cancer research

Pérez-Gómez E,Villa-Morales M,Santos J,Fernández-Piqueras J,Gamallo C,Dotor J,Bernabéu C,Quintanilla M

Thu Nov 01 00:00:00 EDT 2007

Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice.

Journal of immunology (Baltimore, Md. : 1950)

Onoe T,Ohdan H,Tokita D,Shishida M,Tanaka Y,Hara H,Zhou W,Ishiyama K,Mitsuta H,Ide K,Asahara T

Fri Jul 01 00:00:00 EDT 2005

Bioinformatics

Protein Aliases: CD105; Cell surface MJ7/18 antigen; Endoglin; ORW; transmembrane glycoprotein

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Gene Aliases: AI528660; AI662476; CD105; Edg; Endo; Eng; S-endoglin

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UniProt ID: (Mouse) Q63961

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Entrez Gene ID: (Mouse) 13805

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Function(s)

transforming growth factor beta-activated receptor activity transforming growth factor beta receptor, cytoplasmic mediator activity type II transforming growth factor beta receptor binding protein binding galactose binding glycosaminoglycan binding type I transforming growth factor beta receptor binding BMP binding protein homodimerization activity transforming growth factor beta binding transmembrane signal receptor

Process(es)

negative regulation of transcription from RNA polymerase II promoter angiogenesis patterning of blood vessels vasculogenesis response to hypoxia positive regulation of protein phosphorylation negative regulation of endothelial cell proliferation heart looping positive regulation of systemic arterial blood pressure cell migration involved in endocardial cushion formation regulation of transcription, DNA-templated protein phosphorylation cell adhesion transmembrane receptor protein serine/threonine kinase signaling pathway transforming growth factor beta receptor signaling pathway heart development positive regulation of gene expression positive regulation of pathway-restricted SMAD protein phosphorylation cell migration regulation of transforming growth factor beta receptor signaling pathway central nervous system vasculogenesis extracellular matrix disassembly negative regulation of cell migration positive regulation of BMP signaling pathway negative regulation of protein autophosphorylation positive regulation of collagen biosynthetic process intracellular signal transduction wound healing positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter smooth muscle tissue development artery morphogenesis venous blood vessel morphogenesis cell motility negative regulation of nitric-oxide synthase activity cell chemotaxis negative regulation of pathway-restricted SMAD protein phosphorylation extracellular matrix constituent secretion detection of hypoxia

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CD105 (Endoglin) Monoclonal Antibody (MJ7/18), eBioscience™

CD105 (Endoglin) Antibody (14-1051-82) in Flow

Product Details

14-1051-82

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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