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Product Details
PA5-139735
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CD109. Recombinant protein control fragment (Product #RP-89855).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2926737
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: VVSGNKRLKE LSYMVVSRGQ LVAVGKQNST MFSLTPENSW TPKACVIVYY IEDDGEIISD VLKIPVQLVF KNKIKLYWSK VKAEPSEKVS LRISVTQPDS IVGIVAVDKS VNLMNASNDI TMENVVHEL
Target Information
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109; CD109 antigen; Gov platelet alloantigens; p180; Platelet-specific Gov antigen; r150; RP11-525G3.1
Gene Aliases: CD109; CPAMD7; p180; r150
UniProt ID: (Human) Q6YHK3
Entrez Gene ID: (Human) 135228
negative regulation of protein phosphorylation
hair follicle development
negative regulation of keratinocyte proliferation
negative regulation of endopeptidase activity
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of keratinocyte differentiation
negative regulation of wound healing
osteoclast fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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