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Product Details
PA5-115054
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CSF2RA(Accession P15509), corresponding to amino acid residues T119-I169.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899690
Product Specific Information
Antibody detects endogenous levels of total CSF2RA.
Target Information
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD116; CD116 antigen; CDw116; colony stimulating factor 2 receptor alpha chain; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); CSF 2R; GM CSF R alpha; GM-CSF receptor alpha subunit; GM-CSF-R-alpha; GM-CSFRalpha; GMCSFR-alpha; GMR-alpha; granulocyte-macrophage colony stimulating receptor alpha; granulocyte-macrophage colony-stimulating factor receptor alpha chain; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; MGC3848; MGC4838
Gene Aliases: CD116; CDw116; CSF2R; CSF2RA; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; Csfgmra; GM-CSF-R-alpha; GM-CSF-Ra; GM-CSFR; GMCSFR; GMR; SMDP4
UniProt ID: (Human) P15509, (Mouse) Q00941
Entrez Gene ID: (Human) 1438, (Mouse) 12982, (Rat) 652957
MAPK cascade
peptidyl-tyrosine phosphorylation
granulocyte colony-stimulating factor signaling pathway
positive regulation of GTPase activity
cellular protein metabolic process
cellular response to granulocyte macrophage colony-stimulating factor stimulus
cytokine-mediated signaling pathway
response to ethanol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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