Product References
ELMO1 Deficiency Reduces Neutrophil Chemotaxis in Murine Peritonitis.
International journal of molecular sciences
Yu S,Geng X,Liu H,Zhang Y,Cao X,Li B,Yan J
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Sun Apr 30 00:00:00 EDT 2023
Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction.
Communications biology
Breitmeyer R,Vogel S,Heider J,Hartmann SM,Wüst R,Keller AL,Binner A,Fitzgerald JC,Fallgatter AJ,Volkmer H
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Sat Apr 29 00:00:00 EDT 2023
LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.
Journal for immunotherapy of cancer
Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
SARS-CoV-2 Delta (B.1.617.2) variant replicates and induces syncytia formation in human induced pluripotent stem cell-derived macrophages.
PeerJ
Thaweerattanasinp T,Wanitchang A,Saenboonrueng J,Srisutthisamphan K,Wanasen N,Sungsuwan S,Jongkaewwattana A,Chailangkarn T
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Thu Mar 09 00:00:00 EST 2023
Methylation of SPRED1: A New Target in Acute Myeloid Leukemia.
Frontiers in oncology
Su N,Wang Y,Lu X,Xu W,Wang H,Mo W,Pang H,Tang R,Li S,Yan X,Li Y,Zhang R
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Sat Apr 02 00:00:00 EDT 2022
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Journal of oncology
Yi J,Peng F,Zhao J,Gong X
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
miR-204-containing exosomes ameliorate GVHD-associated dry eye disease.
Science advances
Zhou T,He C,Lai P,Yang Z,Liu Y,Xu H,Lin X,Ni B,Ju R,Yi W,Liang L,Pei D,Egwuagu CE,Liu X
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular Carcinoma.
Frontiers in immunology
Gou Y,Yang D,Tian T,Zhu X,Zhang R,Ren J,Tu D,Luo Y,Miao Y,Zhao H,Wang Y,Wei B
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML.
Oncogene
Nicosia L,Boffo FL,Ceccacci E,Conforti F,Pallavicini I,Bedin F,Ravasio R,Massignani E,Somervaille TCP,Minucci S,Bonaldi T
12-0118-42 was used in Flow cytometry/Cell sorting to offer new insights into GSE1 as a novel therapeutic target for acute myeloid leukemia (AML).
Tue Feb 01 00:00:00 EST 2022
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
The Journal of experimental medicine
Louka E,Povinelli B,Rodriguez-Meira A,Buck G,Wen WX,Wang G,Sousos N,Ashley N,Hamblin A,Booth CAG,Roy A,Elliott N,Iskander D,de la Fuente J,Fordham N,O'Byrne S,Inglott S,Norfo R,Salio M,Thongjuea S,Rao A,Roberts I,Mead AJ
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
A peptide derived from chaperonin 60.1, IRL201104, inhibits LPS-induced acute lung inflammation.
American journal of physiology. Lung cellular and molecular physiology
Man F,Nadkarni S,Kanabar V,E-Lacerda RR,Gomes Ferreira S,Federici Canova D,Perretti M,Page CP,Riffo-Vasquez Y
12-0118-42 was used in Flow Cytometry to investigate the anti-inflammatory properties of chaperonin 60.1 (Cpn60.1) and its peptide fragment IRL201104 in a model of nonallergic lung inflammation.
Mon Nov 01 00:00:00 EDT 2021
Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages.
Journal of inflammation research
Lai CY,Tseng PC,Chen CL,Satria RD,Wang YT,Lin CF
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Wed Apr 27 00:00:00 EDT 2022
G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Cell death & disease
Sun SN,Ni SH,Li Y,Liu X,Deng JP,Chen ZX,Li H,Feng WJ,Huang YS,Li DN,Xian SX,Yang ZQ,Wang LJ,Lu L
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Activated CD4+ T cells and CD14hiCD16+ monocytes correlate with antibody response following influenza virus infection in humans.
Cell reports. Medicine
Wong SS,Oshansky CM,Guo XJ,Ralston J,Wood T,Reynolds GE,Seeds R,Jelley L,Waite B,Jeevan T,Zanin M,Widdowson MA,Huang QS,Thomas PG,Webby RJ
12-0118 was used in Flow cytometry/Cell sorting to demonstrate that seroconversion failure after infection is a definable immunological phenomenon, associated with quantifiable cellular markers that can be used to improve diagnostics, vaccine efficacy, and epidemiologic efforts.
Tue Apr 20 00:00:00 EDT 2021
Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease.
NPJ Parkinson's disease
Thome AD,Atassi F,Wang J,Faridar A,Zhao W,Thonhoff JR,Beers DR,Lai EC,Appel SH
12-0118-42 was used in Flow Cytometry to document a shift towards a pro-inflammatory peripheral immune response in patients with Parkinson's disease (PD).
Thu May 13 00:00:00 EDT 2021
Associations between Hypertriglyceridemia and Circulating Neutrophil Subpopulation in Patients with Dyslipidemia.
International journal of inflammation
Genkel V,Dolgushin I,Baturina I,Savochkina A,Kuznetsova A,Pykhova L,Shaposhnik I
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Sun Apr 24 00:00:00 EDT 2022
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
Cancer cell
Su R,Dong L,Li Y,Gao M,Han L,Wunderlich M,Deng X,Li H,Huang Y,Gao L,Li C,Zhao Z,Robinson S,Tan B,Qing Y,Qin X,Prince E,Xie J,Qin H,Li W,Shen C,Sun J,Kulkarni P,Weng H,Huang H,Chen Z,Zhang B,Wu X,Olsen MJ,Müschen M,Marcucci G,Salgia R,Li L,Fathi AT,Li Z,Mulloy JC,Wei M,Horne D,Chen J
12-0118-42 was used in Flow Cytometry to demonstrate if fat mass and obesity-associated protein plays critical roles in cancer stem cell self-renewal and immune evasion.
Mon Jul 13 00:00:00 EDT 2020
Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.
Molecular cell
Psaila B,Wang G,Rodriguez-Meira A,Li R,Heuston EF,Murphy L,Yee D,Hitchcock IS,Sousos N,O'Sullivan J,Anderson S,Senis YA,Weinberg OK,Calicchio ML,Iskander D,Royston D,Milojkovic D,Roberts I,Bodine DM,Thongjuea S,Mead AJ
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Thu May 07 00:00:00 EDT 2020
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Haematologica
Grasedieck S,Ruess C,Krowiorz K,Lux S,Pochert N,Schwarzer A,Klusmann JH,Jongen-Lavrencic M,Herold T,Bullinger L,Pollack JR,Rouhi A,Kuchenbauer F
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells.
Molecular oncology
Orfali N,Shan-Krauer D,O'Donovan TR,Mongan NP,Gudas LJ,Cahill MR,Tschan MP,McKenna SL
12-0118 was used in Flow cytometry/Cell sorting to assess if Ubiquitin-conjugating enzyme E2L6 (UBE2L6) expression is important for leukemic cell differentiation.
Mon Jun 01 00:00:00 EDT 2020
Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation.
Oncogenesis
Zhang CX,Huang DJ,Baloche V,Zhang L,Xu JX,Li BW,Zhao XR,He J,Mai HQ,Chen QY,Zhang XS,Busson P,Cui J,Li J
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
European journal of haematology
Orfali N,O'Donovan TR,Cahill MR,Benjamin D,Nanus DM,McKenna SL,Gudas LJ,Mongan NP
12-0118-42 was used in Flow Cytometry to show for the first time that TFEB plays an important role in ATRA-induced autophagy during myeloid differentiation and that autophagy induction potentiates leukemic cell differentiation.
Sun Mar 01 00:00:00 EST 2020
Connecting METTL3 and intratumoural CD33+ MDSCs in predicting clinical outcome in cervical cancer.
Journal of translational medicine
Ni HH,Zhang L,Huang H,Dai SQ,Li J
12-0118 was used in Flow cytometry/Cell sorting to explore the associations between the levels of methyltransferase-like 3(METTL3) and CD33+ myeloid-derived suppressor cells (MDSCs) in tumour tissues and the survival of patients with cervical cancer (CC).
Thu Oct 15 00:00:00 EDT 2020
Connecting METTL3 and intratumoural CD33+ MDSCs in predicting clinical outcome in cervical cancer.
Journal of translational medicine
Ni HH,Zhang L,Huang H,Dai SQ,Li J
12-0118 was used in Flow cytometry/Cell sorting to explore the associations between the levels of methyltransferase-like 3(METTL3) and CD33+ myeloid-derived suppressor cells (MDSCs) in tumour tissues and the survival of patients with cervical cancer (CC).
Thu Oct 15 00:00:00 EDT 2020
Ubiquitin-specific peptidase 3 induces TPA-mediated leukemia cell differentiation via regulating H2AK119ub.
Animal cells and systems
Chae YC,Jung H,Kim JY,Lee DH,Seo SB
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations.
Scientific reports
Nixon AML,Duque A,Yelle N,McLaughlin M,Davoudi S,Pedley NM,Haynes J,Brown KR,Pan J,Hart T,Gilbert PM,Singh SK,O'Brien CA,Sidhu SS,Moffat J
12-0118 was used in Flow cytometry/Cell sorting to facilitate the rapid identification of novel targets and simultaneous generation of potent and specific antibodies with therapeutic potential.
Tue Jan 29 00:00:00 EST 2019
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
eLife
Nandakumar SK,McFarland SK,Mateyka LM,Lareau CA,Ulirsch JC,Ludwig LS,Agarwal G,Engreitz JM,Przychodzen B,McConkey M,Cowley GS,Doench JG,Maciejewski JP,Ebert BL,Root DE,Sankaran VG
12-0118-42 was used in Flow Cytometry to identify 77 genes at 38 GWAS loci, with most loci harboring 1-2 candidate genes.
Thu May 09 00:00:00 EDT 2019
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.
Cell
Thion MS,Low D,Silvin A,Chen J,Grisel P,Schulte-Schrepping J,Blecher R,Ulas T,Squarzoni P,Hoeffel G,Coulpier F,Siopi E,David FS,Scholz C,Shihui F,Lum J,Amoyo AA,Larbi A,Poidinger M,Buttgereit A,Lledo PM,Greter M,Chan JKY,Amit I,Beyer M,Schultze JL,Schlitzer A,Pettersson S,Ginhoux F,Garel S
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Cancer cell
Maes T,Mascaró C,Tirapu I,Estiarte A,Ciceri F,Lunardi S,Guibourt N,Perdones A,Lufino MMP,Somervaille TCP,Wiseman DH,Duy C,Melnick A,Willekens C,Ortega A,Martinell M,Valls N,Kurz G,Fyfe M,Castro-Palomino JC,Buesa C
12-0118 was used in Flow cytometry/Cell sorting to reveal that ORY-1001 is a selective KDM1A inhibitor in clinical trials and can be evaluated in patients with leukemia and solid tumours.
Mon Mar 12 00:00:00 EDT 2018
AURKA Suppresses Leukemic THP-1 Cell Differentiation through Inhibition of the KDM6B Pathway.
Molecules and cells
Park JW,Cho H,Oh H,Kim JY,Seo SB
12-0118 was used in Flow cytometry/Cell sorting to discover the mechanism of AURKA-KDM6B signaling that controls the differentiation of THP-1 cells, which has implications for biotherapy for leukemia.
Thu May 31 00:00:00 EDT 2018
n-butanol extract from Folium isatidis inhibits the lipopolysaccharide-induced downregulation of CXCR1 and CXCR2 on human neutrophils.
Molecular medicine reports
Wu B,Wang L,Jiang L,Dong L,Xu F,Lu Y,Jin J,Wang Z,Liang G,Shan X
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.
Oncology letters
Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
Deacetylase activity-independent transcriptional activation by HDAC2 during TPA-induced HL-60 cell differentiation.
PloS one
Jung H,Kim JY,Kim KB,Chae YC,Hahn Y,Kim JW,Seo SB
12-0118 was used in Flow cytometry/Cell sorting to elucidate the mechanism underlying the differentiation of HL-60 cells in response to tetradecanoylphorbol-13-acetate.
Thu Feb 07 00:00:00 EST 2019
Microglia innately develop within cerebral organoids.
Nature communications
Ormel PR,Vieira de Sá R,van Bodegraven EJ,Karst H,Harschnitz O,Sneeboer MAM,Johansen LE,van Dijk RE,Scheefhals N,Berdenis van Berlekom A,Ribes Martínez E,Kling S,MacGillavry HD,van den Berg LH,Kahn RS,Hol EM,de Witte LD,Pasterkamp RJ
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Oct 09 00:00:00 EDT 2018
Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells.
Neoplasia (New York, N.Y.)
Bera R,Chiu MC,Huang YJ,Liang DC,Lee YS,Shih LY
12-0118 was used in Flow cytometry/Cell sorting to study the effects of DNMT3A-Arg882His/Cys (R882H/C) mutations in myeloid leukaemia cells.
Thu Nov 01 00:00:00 EDT 2018
Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation.
Cell
Kim AR,Ulirsch JC,Wilmes S,Unal E,Moraga I,Karakukcu M,Yuan D,Kazerounian S,Abdulhay NJ,King DS,Gupta N,Gabriel SB,Lander ES,Patiroglu T,Ozcan A,Ozdemir MA,Garcia KC,Piehler J,Gazda HT,Klein DE,Sankaran VG
12-0118 was used in Flow cytometry/Cell sorting to demonstrate how variation in a single cytokine can lead to biased downstream signaling and can thereby cause human disease.
Thu Mar 09 00:00:00 EST 2017
TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.
Clinical cancer research : an official journal of the American Association for Cancer Research
Petrova PS,Viller NN,Wong M,Pang X,Lin GH,Dodge K,Chai V,Chen H,Lee V,House V,Vigo NT,Jin D,Mutukura T,Charbonneau M,Truong T,Viau S,Johnson LD,Linderoth E,Sievers EL,Maleki Vareki S,Figueredo R,Pampillo M,Koropatnick J,Trudel S,Mbong N,Jin L,Wang JC,Uger RA
12-0118 was used in Flow cytometry/Cell sorting to establish CD47 as a critical regulator of innate immune surveillance and form the basis for clinical development of TTI-621 in multiple oncology indications.
Wed Feb 15 00:00:00 EST 2017
Dyslipidemic Diet-Induced Monocyte "Priming" and Dysfunction in Non-Human Primates Is Triggered by Elevated Plasma Cholesterol and Accompanied by Altered Histone Acetylation.
Frontiers in immunology
Short JD,Tavakoli S,Nguyen HN,Carrera A,Farnen C,Cox LA,Asmis R
12-0118 was used in Flow cytometry/Cell sorting to show that metabolic stress promotes monocyte priming and hyper-chemotactic responses in NHP.
Thu Mar 31 00:00:00 EDT 2022
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
12-0118 was used in Flow cytometry/Cell sorting to demonstrate that BM-derived DC culture systems were heterogeneous, comprising of non-adherent cells, adherent cells, mixed cells and firmly adherent cells.
Wed Nov 01 00:00:00 EDT 2017
The prognostic significance of CD11b+CX3CR1+ monocytes in patients with newly diagnosed diffuse large B-cell lymphoma.
Oncotarget
Yhim HY,Kim JA,Ko SH,Park Y,Yim E,Kim HS,Kwak JY
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Fri Nov 03 00:00:00 EDT 2017
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Wed Jul 27 00:00:00 EDT 2016
Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment.
PloS one
Suenaga G,Ikeda T,Komohara Y,Takamatsu K,Kakuma T,Tasaki M,Misumi Y,Ueda M,Ito T,Senju S,Ando Y
12-0118 was used in Flow cytometry/Cell sorting to evaluate abnormalities in heart tissue-resident macrophages in familial amyloid polyneuropathy.
Thu Jun 15 00:00:00 EDT 2017
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.
Nature medicine
Pallett LJ,Gill US,Quaglia A,Sinclair LV,Jover-Cobos M,Schurich A,Singh KP,Thomas N,Das A,Chen A,Fusai G,Bertoletti A,Cantrell DA,Kennedy PT,Davies NA,Haniffa M,Maini MK
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
The Journal of clinical investigation
Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2015
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.
Experimental hematology
Orfali N,O'Donovan TR,Nyhan MJ,Britschgi A,Tschan MP,Cahill MR,Mongan NP,Gudas LJ,McKenna SL
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Altered translation of GATA1 in Diamond-Blackfan anemia.
Nature medicine
Ludwig LS,Gazda HT,Eng JC,Eichhorn SW,Thiru P,Ghazvinian R,George TI,Gotlib JR,Beggs AH,Sieff CA,Lodish HF,Lander ES,Sankaran VG
12-0118 was used in Flow cytometry/Cell sorting to study the altered translation of GATA1 in cells isolated from patients with Diamond-Blackfan anemia.
Tue Jul 01 00:00:00 EDT 2014
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
12-0118 was used in Flow cytometry/Cell sorting to investigate the role of inductive cues from the vascular niche in coordinating and sustaining haematopoietic specification.
Thu Jul 17 00:00:00 EDT 2014
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
12-0118 was used in Flow cytometry/Cell sorting to investigate the role of inductive cues from the vascular niche in coordinating and sustaining haematopoietic specification.
Thu Jul 17 00:00:00 EDT 2014
Oroxylin A has therapeutic potential in acute myelogenous leukemia by dual effects targeting PPARγ and RXRα.
International journal of cancer
Hui H,Chen Y,Yang H,Zhao K,Wang Q,Zhao L,Wang X,Li Z,Lu N,Guo Q
12-0118 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which oroxylin A has therapeutic potential in acute myelogenous leukaemia treatment.
Sat Mar 01 00:00:00 EST 2014
Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia.
Journal of neuroinflammation
Hendrickx DA,Schuurman KG,van Draanen M,Hamann J,Huitinga I
12-0118 was used in Flow cytometry/Cell sorting to study how microglia enhance their phagocytic capacity for myelin phagocytosis during ageing, but myelin reduces its susceptibility for uptake.
Mon Mar 31 00:00:00 EDT 2014
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies.
The Journal of experimental medicine
Molnarfi N,Schulze-Topphoff U,Weber MS,Patarroyo JC,Prod'homme T,Varrin-Doyer M,Shetty A,Linington C,Slavin AJ,Hidalgo J,Jenne DE,Wekerle H,Sobel RA,Bernard CC,Shlomchik MJ,Zamvil SS
12-0118 was used in Flow cytometry/Cell sorting to investigate the contribution of B cells to antigen presentation and pathogenic T cell activation in the multiple sclerosis model experimental autoimmune encephalomyelitis.
Mon Dec 16 00:00:00 EST 2013
Brucella abortus induces intracellular retention of MHC-I molecules in human macrophages down-modulating cytotoxic CD8(+) T cell responses.
Cellular microbiology
Barrionuevo P,Delpino MV,Pozner RG,Velásquez LN,Cassataro J,Giambartolomei GH
12-0118 was used in Flow cytometry/Cell sorting to study the effect of Brucella abortus infection of human monocytes/macrophages on the IFN-γ-induced MHC-I cell surface expression.
Mon Apr 01 00:00:00 EDT 2013
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) preserves gut barrier function by blocking neutrophil-endothelial cell adhesion after hemorrhagic shock and resuscitation in mice.
Surgery
Zhang HY,James I,Chen CL,Besner GE
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2012
Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.
Journal of immunology (Baltimore, Md. : 1950)
Cross SA,Cook DR,Chi AW,Vance PJ,Kolson LL,Wong BJ,Jordan-Sciutto KL,Kolson DL
12-0118 was used in Flow cytometry/Cell sorting to investigate the effect of HIV infection on macrophage antioxidant response.
Tue Nov 15 00:00:00 EST 2011
Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties.
Neuro-oncology
Rodrigues JC,Gonzalez GC,Zhang L,Ibrahim G,Kelly JJ,Gustafson MP,Lin Y,Dietz AB,Forsyth PA,Yong VW,Parney IF
Published figure using CD11b monoclonal antibody (Product # 12-0118-42) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Divergent adaptive and innate immunological responses are observed in humans following blunt trauma.
BMC immunology
Kasten KR,Goetzman HS,Reid MR,Rasper AM,Adediran SG,Robinson CT,Cave CM,Solomkin JS,Lentsch AB,Johannigman JA,Caldwell CC
12-0118 was used in Flow cytometry/Cell sorting to suggest that trauma is followed by hyper- and hypo-inflammatory responses from the innate and adaptive immune system respectively.
Mon Jan 25 00:00:00 EST 2010
Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9.
PloS one
Yassin ER,Sarma NJ,Abdul-Nabi AM,Dombrowski J,Han Y,Takeda A,Yaseen NR
12-0118 was used in Flow cytometry/Cell sorting to investigate the role of NUP98-HOXA9 in haematopoietic cells.
Fri Aug 21 00:00:00 EDT 2009
Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression.
Cancer science
Zhang K,Guo QL,You QD,Yang Y,Zhang HW,Yang L,Gu HY,Qi Q,Tan Z,Wang X
12-0118 was used in Flow cytometry/Cell sorting to investigate the potential role of wogonin in the proliferation and differentiation of an acute promyelocytic leukaemia cell line.
Tue Apr 01 00:00:00 EDT 2008
Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms.
Journal of leukocyte biology
Nakayama H,Yoshizaki F,Prinetti A,Sonnino S,Mauri L,Takamori K,Ogawa H,Iwabuchi K
12-0118 was used in Flow cytometry/Cell sorting to suggest that CD11b activation causes translocation of CD11b/CD18 into Lyn-coupled, LacCer-enriched lipid rafts, allowing neutrophils to phagocytose NOZs via CD11b/CD18.
Sat Mar 01 00:00:00 EST 2008
Electrophysiological properties of human adipose tissue-derived stem cells.
American journal of physiology. Cell physiology
Bai X,Ma J,Pan Z,Song YH,Freyberg S,Yan Y,Vykoukal D,Alt E
12-0118 was used in Flow cytometry/Cell sorting to investigate ionic channel currents present in undifferentiated human adipose tissue-derived stem cells (hASCs) and their impact on hASC proliferation.
Thu Nov 01 00:00:00 EDT 2007
Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells.
Journal of virology
Xin KQ,Mizukami H,Urabe M,Toda Y,Shinoda K,Yoshida A,Oomura K,Kojima Y,Ichino M,Klinman D,Ozawa K,Okuda K
12-0118 was used in Flow cytometry/Cell sorting to investigate the ability of different adeno-associated virus vectors expressing the human immunodeficiency virus to induce a robust immune response, and the factors which affect this.
Fri Dec 01 00:00:00 EST 2006
