Product References
The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer.
Cell reports
An HW,Seok SH,Kwon JW,Choudhury AD,Oh JS,Voon DC,Kim DY,Park JW
12-1331-82 was used in Flow cytometry/Cell sorting to report that the loss of Smad4 expression in GC cells endows them with the ability to evade tumor immunity and provide a rational basis for ICB strategies in treating advanced GC with Smad4 deficiency.
Tue Dec 27 00:00:00 EST 2022
Analyzing mouse neural stem cell and progenitor cell proliferation using EdU incorporation and multicolor flow cytometry.
STAR protocols
Velloso FJ,Kumari E,Buono KD,Frondelli MJ,Levison SW
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2022
C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer.
Nature communications
Liu XZ,Rulina A,Choi MH,Pedersen L,Lepland J,Takle ST,Madeleine N,Peters SD,Wogsland CE,Grøndal SM,Lorens JB,Goodarzi H,Lønning PE,Knappskog S,Molven A,Halberg N
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Mon Jan 10 00:00:00 EST 2022
FUBP1 promotes colorectal cancer stemness and metastasis via DVL1-mediated activation of Wnt/β-catenin signaling.
Molecular oncology
Yin H,Gao T,Xie J,Huang Z,Zhang X,Yang F,Qi W,Yang Z,Zhou T,Gao G,Yang X
12-1331-82 was used in Flow Cytometry to demonstrate, for the first time, that FUBP1 is an oncogene, initiating the development of CSCs, as well as a new powerful endogenous Wnt-signaling agonist that could provide an important prognostic factor and therapeutic target for metastasis in both KRAS-mutant and wild-type CRC.
Wed Dec 01 00:00:00 EST 2021
Endothelial GABBR2 Regulates Post-ischemic Angiogenesis by Inhibiting the Glycolysis Pathway.
Frontiers in cardiovascular medicine
Zhang H,Zhou H,Yuan J,Nan Y,Liu J
12-1331-82 was used in Flow cytometry/Cell sorting to determine the regulatory mechanism of ischemic angiogenesis and to verify the role of GABBR2 in angiogenesis.
Tue Aug 24 00:00:00 EDT 2021
Cell population analysis of the adult murine subependymal neurogenic lineage by flow cytometry.
STAR protocols
Belenguer G,Duart-Abadia P,Domingo-Muelas A,Morante-Redolat JM,Fariñas I
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium.
Development (Cambridge, England)
Gagniac L,Rusidzé M,Boudou F,Cagnet S,Adlanmerini M,Jeannot P,Gaide N,Giton F,Besson A,Weyl A,Gourdy P,Raymond-Letron I,Arnal JF,Brisken C,Lenfant F
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Wed Mar 11 00:00:00 EDT 2020
Rapamycin and dexamethasone during pregnancy prevent tuberous sclerosis complex-associated cystic kidney disease.
JCI insight
Nechama M,Makayes Y,Resnick E,Meir K,Volovelsky O
12-1331 was used in Flow cytometry/Cell sorting to showed that cysts in TSC1-null embryonic kidneys originate from injured proximal tubular cells with high mTOR complex 1 activity.
Thu Jul 09 00:00:00 EDT 2020
Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies.
Cell reports
Kim IS,Wu J,Rahme GJ,Battaglia S,Dixit A,Gaskell E,Chen H,Pinello L,Bernstein BE
12-1331 was used in Flow cytometry/Cell sorting to characterize embryoid bodies differentiation by combining single-cell transcriptomics and genetic recording.
Tue Oct 06 00:00:00 EDT 2020
Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells.
PloS one
Robson JP,Remke M,Kool M,Julian E,Korshunov A,Pfister SM,Osborne GW,Taylor MD,Wainwright B,Reynolds BA
12-1331 was used in Flow cytometry/Cell sorting to identify and isolate tumour-initiating cell populations in Patched1 deleted medulloblastoma, and determine if these antibodies can help classify the identity of human medulloblastoma subgroups.
Fri Oct 18 00:00:00 EDT 2019
Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development.
Cell reports
Komabayashi-Suzuki M,Yamanishi E,Watanabe C,Okamura M,Tabata H,Iwai R,Ajioka I,Matsushita J,Kidoya H,Takakura N,Okamoto T,Kinoshita K,Ichihashi M,Nagata KI,Ema M,Mizutani KI
Tue Oct 29 00:00:00 EDT 2019
Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.
The Journal of investigative dermatology
Philippeos C,Telerman SB,Oulès B,Pisco AO,Shaw TJ,Elgueta R,Lombardi G,Driskell RR,Soldin M,Lynch MD,Watt FM
12-1331 was used in Flow cytometry/Cell sorting to suggest that ex vivo expansion or in vivo ablation of specific fibroblast subpopulations may have therapeutic applications in wound healing and diseases characterized by excessive fibrosis.
Sun Apr 01 00:00:00 EDT 2018
Epigenome profiling and editing of neocortical progenitor cells during development.
The EMBO journal
Albert M,Kalebic N,Florio M,Lakshmanaperumal N,Haffner C,Brandl H,Henry I,Huttner WB
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.
Cancer research
Zhu G,Rankin SL,Larson JD,Zhu X,Chow LM,Qu C,Zhang J,Ellison DW,Baker SJ
12-1331 was used in Immunohistochemistry to investigate the impact of conditionally inactivating PTEN in neonatal neural stem and progenitor cells.
Sun Jan 01 00:00:00 EST 2017
The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Development (Cambridge, England)
Yang YP,Magnuson MA,Stein R,Wright CV
12-1331 was used in Flow cytometry/Cell sorting to show that Area II of 5' conserved cis-regulatory regions of transcription factor Pdx1 is a primary effector of developmental endocrine-selective transcription across multiple cell lines.
Sun Jan 15 00:00:00 EST 2017
Differentiation of Islet Progenitors Regulated by Nicotinamide into Transcriptome-Verified β Cells That Ameliorate Diabetes.
Stem cells (Dayton, Ohio)
Jiang FX,Li K,Archer M,Mehta M,Jamieson E,Charles A,Dickinson JE,Matsumoto M,Morahan G
12133182 was used in flow cytometry to find that the multi-functional molecule nicotinamide is a specific differentiation regulator of mouse islet progenitor cells
Mon May 01 00:00:00 EDT 2017
The C-terminus domain of the hepatitis B virus x protein stimulates the proliferation of mouse foetal hepatic progenitor cells, although it is not required for the formation of spheroids.
International journal of molecular medicine
Yu L,Chen S,Luo N,He S
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Isolation of cancer progenitor cells from cancer stem cells in gastric cancer.
Molecular medicine reports
Shang Z,Xu Y,Liang W,Liang K,Hu X,Wang L,Zou Z,Ma Y
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Intravenous Arginine Administration Promotes Proangiogenic Cells Mobilization and Attenuates Lung Injury in Mice with Polymicrobial Sepsis.
Nutrients
Yeh CL,Pai MH,Shih YM,Shih JM,Yeh SL
12-1331 was used in Flow cytometry/Cell sorting to study the potential beneficial effects of intravenous administration of Arginine shortly after the onset of sepsis in mice.
Wed May 17 00:00:00 EDT 2017
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Stem Cells Antigen-1 Enriches for a Cancer Stem Cell-Like Subpopulation in Mouse Gastric Cancer.
Stem cells (Dayton, Ohio)
Park JW,Park JM,Park DM,Kim DY,Kim HK
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
ECM-Dependence of Endothelial Progenitor Cell Features.
Journal of cellular biochemistry
Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Macrophages form functional vascular mimicry channels in vivo.
Scientific reports
Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Fri Nov 11 00:00:00 EST 2016
Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor.
Scientific reports
Weng L,Hu X,Kumar B,Garcia M,Todorov I,Jung X,Marcucci G,Forman SJ,Chen CC
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Thu Dec 08 00:00:00 EST 2016
IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process.
Oncotarget
Le Coz V,Zhu C,Devocelle A,Vazquez A,Boucheix C,Azzi S,Gallerne C,Eid P,Lecourt S,Giron-Michel J
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Tue Dec 13 00:00:00 EST 2016
Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133).
PloS one
Thamm K,Graupner S,Werner C,Huttner WB,Corbeil D
12-1331 was used in Flow cytometry/Cell sorting to clone the canine prominin-1 and use its overexpression as a green fluorescent protein fusion protein in Madin-Darby canine kidney cells to determine its immunoreactivity with antibodies against human or mouse prominin-1.
Mon Jun 19 00:00:00 EDT 2017
Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133).
PloS one
Thamm K,Graupner S,Werner C,Huttner WB,Corbeil D
12-1331 was used in Flow cytometry/Cell sorting to clone the canine prominin-1 and use its overexpression as a green fluorescent protein fusion protein in Madin-Darby canine kidney cells to determine its immunoreactivity with antibodies against human or mouse prominin-1.
Mon Jun 19 00:00:00 EDT 2017
Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133).
PloS one
Thamm K,Graupner S,Werner C,Huttner WB,Corbeil D
12-1331 was used in Flow cytometry/Cell sorting to clone the canine prominin-1 and use its overexpression as a green fluorescent protein fusion protein in Madin-Darby canine kidney cells to determine its immunoreactivity with antibodies against human or mouse prominin-1.
Mon Jun 19 00:00:00 EDT 2017
MiR-139-5p reverses CD44+/CD133+-associated multidrug resistance by downregulating NOTCH1 in colorectal carcinoma cells.
Oncotarget
Xu K,Shen K,Liang X,Li Y,Nagao N,Li J,Liu J,Yin P
12-1331 was used in Flow cytometry/Cell sorting to provide insight into the miRNA regulation of multiple drug resistance (MDR) through a newly established MDR cell model.
Tue Nov 15 00:00:00 EST 2016
Lysophosphatidic Acid Receptor Is a Functional Marker of Adult Hippocampal Precursor Cells.
Stem cell reports
Walker TL,Overall RW,Vogler S,Sykes AM,Ruhwald S,Lasse D,Ichwan M,Fabel K,Kempermann G
12-1331 was used in Flow cytometry/Cell sorting to show that lysophosphatidic acid receptor 1 is expressed by type 1 stem cells and type 2a precursor cells in mouse dentate gyrus.
Tue Apr 12 00:00:00 EDT 2016
Single-cell transcriptome analyses reveal signals to activate dormant neural stem cells.
Cell
Luo Y,Coskun V,Liang A,Yu J,Cheng L,Ge W,Shi Z,Zhang K,Li C,Cui Y,Lin H,Luo D,Wang J,Lin C,Dai Z,Zhu H,Zhang J,Liu J,Liu H,deVellis J,Horvath S,Sun YE,Li S
Thu May 21 00:00:00 EDT 2015
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors.
Journal of medicinal chemistry
Wu CH,Wang CJ,Chang CP,Cheng YC,Song JS,Jan JJ,Chou MC,Ke YY,Ma J,Wong YC,Hsieh TC,Tien YC,Gullen EA,Lo CF,Cheng CY,Liu YW,Sadani AA,Tsai CH,Hsieh HP,Tsou LK,Shia KS
12-1331 was used in Flow cytometry/Cell sorting to identify a CXCR4 antagonist for anti-HIV therapeutics, producing a purine-based antagonist, compound 24, with a subnanomolar EC50 value.
Thu Feb 12 00:00:00 EST 2015
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
12-1331 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
A double blinded, placebo-controlled pilot study to examine reduction of CD34 +/CD117 +/CD133 + lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma.
F1000Research
Ito D,Childress M,Mason N,Winter A,O'Brien T,Henson M,Borgatti A,Lewellen M,Krick E,Stewart J,Lahrman S,Rajwa B,Scott MC,Seelig D,Koopmeiners J,Ruetz S,Modiano J
12-1331 was used in Flow cytometry/Cell sorting to examine whether ABCB1 would reduce lymphoma progenitor cells, and extend the length of remission in dogs with therapy naive large B-cell lymphoma.
Tue Sep 14 00:00:00 EDT 2021
Mesenchymal-endothelial transition contributes to cardiac neovascularization.
Nature
Ubil E,Duan J,Pillai IC,Rosa-Garrido M,Wu Y,Bargiacchi F,Lu Y,Stanbouly S,Huang J,Rojas M,Vondriska TM,Stefani E,Deb A
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Thu Oct 30 00:00:00 EDT 2014
Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Nature
Adorno M,Sikandar S,Mitra SS,Kuo A,Nicolis Di Robilant B,Haro-Acosta V,Ouadah Y,Quarta M,Rodriguez J,Qian D,Reddy VM,Cheshier S,Garner CC,Clarke MF
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Thu Sep 19 00:00:00 EDT 2013
The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities.
Journal of neurochemistry
Kao CY,Hsu YC,Liu JW,Lee DC,Chung YF,Chiu IM
12-1331 was used in Flow cytometry/Cell sorting to suggest that VPA activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities.
Mon Jul 01 00:00:00 EDT 2013
Identification of cell surface antigen expression in canine hepatocellular carcinoma cell lines.
The Journal of veterinary medical science
Fujimoto A,Neo S,Ishizuka C,Kato T,Segawa K,Kawarai S,Ogihara K,Hisasue M,Tsuchiya R
12-1331-82 was used in flow cytometry to indicate that CD29, CD44, CD133 and Dlk-1 have potential as suitable markers in cHCC identification, suggesting that these findings will contribute to the establishment of an early diagnostic tool for the identification of hepatocellular maturation processes.
Tue Jan 28 00:00:00 EST 2014
WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum.
Development (Cambridge, England)
Pei Y,Brun SN,Markant SL,Lento W,Gibson P,Taketo MM,Giovannini M,Gilbertson RJ,Wechsler-Reya RJ
12-1331 was used in Flow cytometry/Cell sorting to investigate how the WNT pathway is a potent regulator of cerebellar stem cell growth and differentiation.
Tue May 01 00:00:00 EDT 2012
Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.
Tissue engineering. Part A
Agrawal V,Siu BF,Chao H,Hirschi KK,Raborn E,Johnson SA,Tottey S,Hurley KB,Medberry CJ,Badylak SF
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2012
Sphere culture of murine lung cancer cell lines are enriched with cancer initiating cells.
PloS one
Morrison BJ,Steel JC,Morris JC
12-1331 was used in Flow cytometry/Cell sorting to examine the sphere-forming capacity of thirteen murine lung cancer cell lines.
Tue May 07 00:00:00 EDT 2013
Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential.
Breast cancer research : BCR
Kittrell FS,Carletti MZ,Kerbawy S,Heestand J,Xian W,Zhang M,Lamarca HL,Sonnenberg A,Rosen JM,Medina D,Behbod F
12-1331 was used in Flow cytometry/Cell sorting to identify and analyse distinct, immortalised mammary progenitor cells.
Tue Apr 05 00:00:00 EDT 2011
Oxidized low-density lipoprotein and β-glycerophosphate synergistically induce endothelial progenitor cell ossification.
Acta pharmacologica Sinica
Liu L,Liu ZZ,Chen H,Zhang GJ,Kong YH,Kang XX
12-1331 was used in Flow cytometry/Cell sorting to discover that Ox-LDL and β-GP synergistically induce ossification of bone marrow-derived endothelial progenitor cells via an oxidative mechanism.
Thu Dec 01 00:00:00 EST 2011
Regeneration of irradiated salivary glands with stem cell marker expressing cells.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Nanduri LS,Maimets M,Pringle SA,van der Zwaag M,van Os RP,Coppes RP
12-1331 was used in Flow cytometry/Cell sorting to characterize the stem/progenitor cell population with regenerative potential residing in the mouse salivary gland.
Wed Jun 01 00:00:00 EDT 2011
Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction.
Circulation. Cardiovascular imaging
Swijnenburg RJ,Govaert JA,van der Bogt KE,Pearl JI,Huang M,Stein W,Hoyt G,Vogel H,Contag CH,Robbins RC,Wu JC
12-1331 was used in Flow cytometry/Cell sorting to show in general, there is poor long-term engraftment and bone marrow mononuclear cells tend to adopt inflammatory cell phenotypes.
Fri Jan 01 00:00:00 EST 2010
Characterization of endothelial progenitor cells mobilization following cutaneous wounding.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Morris LM,Klanke CA,Lang SA,Pokall S,Maldonado AR,Vuletin JF,Alaee D,Keswani SG,Lim FY,Crombleholme TM
12-1331 was used in Flow cytometry/Cell sorting to characterize bone marrow (BM)-derived endothelial progenitor cell (EPC) mobilization following cutaneous wounding in mice.
Mon Nov 15 00:00:00 EST 2010
Characterization of fibroblasts responsible for cartilage destruction in arthritis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Treese C,Mittag A,Lange F,Tarnok A,Loesche A,Emmrich F,Lehmann J,Sack U
12-1331 was used in Flow cytometry/Cell sorting to show that LS48 is an excellent tool to gain a deeper understanding of synovial fibroblasts in rheumatoid arthritis.
Tue Apr 01 00:00:00 EDT 2008
CD133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells.
Cancer research
Pfenninger CV,Roschupkina T,Hertwig F,Kottwitz D,Englund E,Bengzon J,Jacobsen SE,Nuber UA
Fri Jun 15 00:00:00 EDT 2007
Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS.
Proceedings of the National Academy of Sciences of the United States of America
Sugiyama T,Rodriguez RT,McLean GW,Kim SK
Published figure using CD133 (Prominin-1) monoclonal antibody (Product # 12-1331-82) in Flow Cytometry
Tue Jan 02 00:00:00 EST 2007