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Product Details
MA5-23527
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
300506
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Syndecan-1/CD138 isoform 1 Gln18-Glu252
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
Buffered saline solution with BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609280
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human Syndecan-1, recombinant mouse (rm) Syndecan-3 or rmSyndecan-4 is observed.
Target Information
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD antigen 138; CD138; sCD138; soluble CD138; SYND1; Syndecan-1; Syndecan1; synstatin
Gene Aliases: AA408134; AA409076; CD138; Sdc1; Sstn; syn-1; Synd; Synd-1; Synd1
UniProt ID: (Mouse) P18828
Entrez Gene ID: (Mouse) 20969
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