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Product Details
PA5-29787
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 100 and 323 of Human CD147
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547261
Product Specific Information
Recommended positive controls: K562, THP-1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5F7; Basigin; CD147; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; HAb18G; Hepatoma-associated antigen; Leukocyte activation antigen M6; OK blood group antigen; TCSF; Tumor cell-derived collagenase stimulatory factor
Gene Aliases: 5F7; BSG; CD147; EMMPRIN; OK; TCSF; UNQ6505/PRO21383
UniProt ID: (Human) P35613
Entrez Gene ID: (Human) 682
pyruvate metabolic process
cell surface receptor signaling pathway
embryo implantation
monocarboxylic acid transport
extracellular matrix disassembly
extracellular matrix organization
odontogenesis of dentin-containing tooth
response to peptide hormone
response to mercury ion
decidualization
leukocyte migration
response to cAMP
protein targeting to plasma membrane
cell-cell adhesion
Performance Guarantee
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