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Invitrogen
CD147 Recombinant Rabbit Monoclonal Antibody (23GB1460)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
CD147 Antibody (MA5-54218) in ICC/IF
Immunocytochemistry analysis of CD147 in HepG2 cells. Nuclei were stained blue with DAPI; CD147 recombinant monoclonal antibody (Product # MA5-54218) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-54218
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB1460
Immunogen
A synthesized peptide derived from human CD147 (150-200AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5A11/Basigin; 5F7; Basic immunoglobulin superfamily; Basigin; Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); CD147; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; HAb18G; Hepatoma-associated antigen; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK blood group antigen; OX-47 antigen; TCSF; Tumor cell-derived collagenase stimulatory factor
Gene Aliases: 5A11; 5F7; AI115436; AI325119; basignin; BSG; CD147; CE9; EMMPRIN; HT-7; HT7; OK; Ox47R; TCSF; UNQ6505/PRO21383
UniProt ID: (Human) P35613, (Mouse) P18572, (Rat) P26453
Entrez Gene ID: (Human) 682, (Mouse) 12215, (Rat) 25246
pyruvate metabolic process
cell surface receptor signaling pathway
embryo implantation
monocarboxylic acid transport
extracellular matrix disassembly
extracellular matrix organization
odontogenesis of dentin-containing tooth
response to peptide hormone
response to mercury ion
decidualization
leukocyte migration
response to cAMP
protein targeting to plasma membrane
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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