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Invitrogen
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5A11/Basigin; 5F7; Basic immunoglobulin superfamily; Basigin; Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); CD147; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; HAb18G; Hepatoma-associated antigen; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK blood group antigen; OX-47 antigen; TCSF; Tumor cell-derived collagenase stimulatory factor
Gene Aliases: 5A11; 5F7; AI115436; AI325119; basignin; BSG; CD147; CE9; EMMPRIN; HT-7; HT7; OK; Ox47R; TCSF; UNQ6505/PRO21383
UniProt ID: (Human) P35613, (Mouse) P18572, (Rat) P26453
Entrez Gene ID: (Human) 682, (Mouse) 12215, (Rat) 25246
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