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CD151 Antibody (PA5-95996) in IHC (P)
Immunohistochemistry analysis of CD151 in paraffin-embedded human lung cancer. Samples were incubated with CD151 Polyclonal antibody (Product # PA5-95996) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-95996
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 113-221 of human CD151 (NP_0043482)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807798
Product Specific Information
Immunogen sequence: AYYQQLNTEL KENLKDTMTK RYHQPGHEAV TSAVDQLQQE FHCCGSNNSQ DWRDSEWIRS QEAGGRVVPD SCCKTVVALC GQRDHASNIY KVEGGCITKL ETFIQEHLR; Positive Samples: Mouse skeletal muscle; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD 151; CD151; CD151 antigen; CD151 antigen (Raph blood group); CD151 molecule; GP27; hemidesmosomal tetraspanin CD151; Membrane glycoprotein SFA-1; PETA-3; platelet endothelial tetraspan antigen-3; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; Platelet-endothelial tetraspan antigen 3; Tetraspanin-24; Tspan-24
Gene Aliases: CD151; GP27; MER2; PETA-3; Peta3; RAPH; SFA-1; SFA1; TSPAN24
UniProt ID: (Human) P48509, (Rat) Q9QZA6, (Mouse) O35566
Entrez Gene ID: (Human) 977, (Rat) 64315, (Mouse) 12476
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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