Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
CD155 Antibody (PA5-96414) in WB
Western blot analysis of CD155 in various lysates. Samples were incubated with CD155 Polyclonal antibody (Product # PA5-96414) using a dilution of 1:400, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
PA5-96414
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human CD155/PVR (NP_0064964?)
Conjugate
Form
Liquid
Concentration
3.82 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808216
Product Specific Information
Positive Samples: LO2; Cellular Location: Cell membrane, Single-pass type I membrane protein
Immunogen sequence: TCKVEHESFE KPQLLTVNLT VYYPPEVSIS GYDNNWYLGQ NEATLTCDAR SNPEPTGYNW STTMGPLPPF AVAQGAQLLI RPVDKPINTT LICNVTNALG ARQAELTVQV KEGPPSEHSG MSRNAI
Target Information
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD155; FLJ25946; NECL-5; nectin-like 5; Nectin-like protein 5; Poliovirus receptor; sCD112; soluble CD112; tumor-associated antigen 1
Gene Aliases: 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; Necl-5; NECL5; PVR; PVS; Taa1; TAGE4
UniProt ID: (Human) P15151
Entrez Gene ID: (Human) 5817, (Mouse) 52118
single organismal cell-cell adhesion
cell migration
viral entry into host cell
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
cell recognition
adherens junction organization
susceptibility to natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
susceptibility to T cell mediated cytotoxicity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support