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Product Details
MA5-29852
Product Specifications
Species Reactivity
Rhesus monkey
Host/Isotype
Mouse
Class
Monoclonal
Type
Antibody
Clone
05
Immunogen
Recombinant Rhesus CD16/Fc gamma RIII Protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785669
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Rhesus CD16/Fc gamma RIII.
Target Information
CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD16A; CD16B; CD32 receptor 2; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc gamma receptor RII; Fc gamma RIIIa; Fc-gamma RIII; Fc-gamma RIII-alpha; FCG2; FCGR2C; FCGR3A; FCGR3B; FCGRIII; FCR-10; FcRII-b; FcRII-c; FCRIIIA; FGFR2B; IgG Fc receptor III; IgG Fc receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-A; RP11-5K23.1
Gene Aliases: CD16; CD32B; FCGR3; FCGR3A; FcRIII
UniProt ID: (Rhesus monkey) A3RFZ7
Entrez Gene ID: (Rhesus monkey) 720009, (Rhesus monkey) 720006
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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