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Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human CD162 (PSGL-1) (Met1-Gly295) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Protein Aliases: CD162; Cutaneous lymphocyte associated antigen; cutaneous lymphocyte-associated associated antigen; P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; SELPG
Gene Aliases: CD162; CLA; PSGL-1; PSGL1; SELPLG
UniProt ID: (Human) Q14242
Entrez Gene ID: (Human) 6404
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