Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CD169 Monoclonal Antibody (ED3)
FIGURE: 1 / 2
CD169 Antibody (MA1-80164) in ICC/IF
The Journal of comparative neurology 2020 -
LYVE-1 positive cells are CD68 or CD169 positive macrophages. (a-g) Brain dura mater of rats were stained for CD68 (red) and lymphatic vessel marker Lyve-1 (green) and nuclear visualization with DAPI (a; blue). Representative picture showing presence of multiple double positive Lyve-1+CD68+ macrophages in the lymphatic lining or in the nonlymphatic areas in the brain dura mater. We also observed several CD6... View More
Product Details
MA1-80164
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
ED3
Immunogen
Rat Spleen cell homogenate.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2189150
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti rat CD169 antibody, clone ED3 recognizes the rat CD169 cell surface antigen, a approximately 185 kDa molecule expressed by macrophages, predominately confined to lymphoid organs only.
Target Information
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support