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Invitrogen
FIGURE: 1 / 1
Specificity: This antibody specifically recognize mouse CD169, which is a 180-185-kDa member of the Siglec family of macrophage-specific cell adhesion and endocytic receptors interacting with sialylated glycans. This receptor is expressed on a subset of macrophages that are found with high frequency in the spleen, liver, lymph node, and bone marrow. CD169 can also be detected on monocytes in the bone marrow and periphery.
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD169; SER; Sheep erythrocyte receptor; Sialic acid-binding Ig-like lectin 1; Sialoadhesin; Siglec-1
Gene Aliases: Cd169; Sa; Siglec-1; Siglec1; Sn
UniProt ID: (Mouse) Q62230
Entrez Gene ID: (Mouse) 20612
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