Product References
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.
Nature immunology
Xu Q,Milanez-Almeida P,Martins AJ,Radtke AJ,Hoehn KB,Oguz C,Chen J,Liu C,Tang J,Grubbs G,Stein S,Ramelli S,Kabat J,Behzadpour H,Karkanitsa M,Spathies J,Kalish H,Kardava L,Kirby M,Cheung F,Preite S,Duncker PC,Kitakule MM,Romero N,Preciado D,Gitman L,Koroleva G,Smith G,Shaffer A,McBain IT,McGuire PJ,Pittaluga S,Germain RN,Apps R,Schwartz DM,Sadtler K,Moir S,Chertow DS,Kleinstein SH,Khurana S,Tsang JS,Mudd P,Schwartzberg PL,Manthiram K
MHCD2030 was used in Flow cytometry/Cell sorting to provide evidence for persistent tissue-specific immunity to SARS-CoV-2 in the upper respiratory tract of children after infection.
Sun Jan 01 00:00:00 EST 2023
Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency.
The Journal of experimental medicine
Ogishi M,Arias AA,Yang R,Han JE,Zhang P,Rinchai D,Halpern J,Mulwa J,Keating N,Chrabieh M,Lainé C,Seeleuthner Y,Ramírez-Alejo N,Nekooie-Marnany N,Guennoun A,Muller-Fleckenstein I,Fleckenstein B,Kilic SS,Minegishi Y,Ehl S,Kaiser-Labusch P,Kendir-Demirkol Y,Rozenberg F,Errami A,Zhang SY,Zhang Q,Bohlen J,Philippot Q,Puel A,Jouanguy E,Pourmoghaddas Z,Bakhtiar S,Willasch AM,Horneff G,Llanora G,Shek LP,Chai LYA,Tay SH,Rahimi HH,Mahdaviani SA,Nepesov S,Bousfiha AA,Erdeniz EH,Karbuz A,Marr N,Navarrete C,Adeli M,Hammarstrom L,Abolhassani H,Parvaneh N,Al Muhsen S,Alosaimi MF,Alsohime F,Nourizadeh M,Moin M,Arnaout R,Alshareef S,El-Baghdadi J,Genel F,Sherkat R,Kiykim A,Yücel E,Keles S,Bustamante J,Abel L,Casanova JL,Boisson-Dupuis S
MHCD2030 was used in Flow cytometry/Cell sorting to show that partial TYK2 deficiency across signaling pathways, or rare or common partial TYK2 deficiency specific for IL-23 signaling.
Mon Oct 03 00:00:00 EDT 2022
Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19.
Immunity
Szabo PA,Dogra P,Gray JI,Wells SB,Connors TJ,Weisberg SP,Krupska I,Matsumoto R,Poon MML,Idzikowski E,Morris SE,Pasin C,Yates AJ,Ku A,Chait M,Davis-Porada J,Guo XV,Zhou J,Steinle M,Mackay S,Saqi A,Baldwin MR,Sims PA,Farber DL
MHCD2030 was used in Flow Cytometry to examine the relationship between immune processes in the respiratory tract and circulation through longitudinal phenotypic, transcriptomic, and cytokine profiling of paired airway and blood samples from patients with severe COVID-19 relative to heathy controls.
Tue Apr 13 00:00:00 EDT 2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Science immunology
Asano T,Boisson B,Onodi F,Matuozzo D,Moncada-Velez M,Maglorius Renkilaraj MRL,Zhang P,Meertens L,Bolze A,Materna M,Korniotis S,Gervais A,Talouarn E,Bigio B,Seeleuthner Y,Bilguvar K,Zhang Y,Neehus AL,Ogishi M,Pelham SJ,Le Voyer T,Rosain J,Philippot Q,Soler-Palacín P,Colobran R,Martin-Nalda A,Rivière JG,Tandjaoui-Lambiotte Y,Chaïbi K,Shahrooei M,Darazam IA,Olyaei NA,Mansouri D,Hatipoğlu N,Palabiyik F,Ozcelik T,Novelli G,Novelli A,Casari G,Aiuti A,Carrera P,Bondesan S,Barzaghi F,Rovere-Querini P,Tresoldi C,Franco JL,Rojas J,Reyes LF,Bustos IG,Arias AA,Morelle G,Christèle K,Troya J,Planas-Serra L,Schlüter A,Gut M,Pujol A,Allende LM,Rodriguez-Gallego C,Flores C,Cabrera-Marante O,Pleguezuelo DE,de Diego RP,Keles S,Aytekin G,Akcan OM,Bryceson YT,Bergman P,Brodin P,Smole D,Smith CIE,Norlin AC,Campbell TM,Covill LE,Hammarström L,Pan-Hammarström Q,Abolhassani H,Mane S,Marr N,Ata M,Al Ali F,Khan T,Spaan AN,Dalgard CL,Bonfanti P,Biondi A,Tubiana S,Burdet C,Nussbaum R,Kahn-Kirby A,Snow AL,Bustamante J,Puel A,Boisson-Dupuis S,Zhang SY,Béziat V,Lifton RP,Bastard P,Notarangelo LD,Abel L,Su HC,Jouanguy E,Amara A,Soumelis V,Cobat A,Zhang Q,Casanova JL
MHCD2030 was used in Flow Cytometry to report very rare, biochemically deleterious X-linked TLR7 variants in 16 unrelated male individuals with unexplained critical COVID-19 pneumonia.
Thu Aug 19 00:00:00 EDT 2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Science immunology
Asano T,Boisson B,Onodi F,Matuozzo D,Moncada-Velez M,Maglorius Renkilaraj MRL,Zhang P,Meertens L,Bolze A,Materna M,Korniotis S,Gervais A,Talouarn E,Bigio B,Seeleuthner Y,Bilguvar K,Zhang Y,Neehus AL,Ogishi M,Pelham SJ,Le Voyer T,Rosain J,Philippot Q,Soler-Palacín P,Colobran R,Martin-Nalda A,Rivière JG,Tandjaoui-Lambiotte Y,Chaïbi K,Shahrooei M,Darazam IA,Olyaei NA,Mansouri D,Hatipoğlu N,Palabiyik F,Ozcelik T,Novelli G,Novelli A,Casari G,Aiuti A,Carrera P,Bondesan S,Barzaghi F,Rovere-Querini P,Tresoldi C,Franco JL,Rojas J,Reyes LF,Bustos IG,Arias AA,Morelle G,Christèle K,Troya J,Planas-Serra L,Schlüter A,Gut M,Pujol A,Allende LM,Rodriguez-Gallego C,Flores C,Cabrera-Marante O,Pleguezuelo DE,de Diego RP,Keles S,Aytekin G,Akcan OM,Bryceson YT,Bergman P,Brodin P,Smole D,Smith CIE,Norlin AC,Campbell TM,Covill LE,Hammarström L,Pan-Hammarström Q,Abolhassani H,Mane S,Marr N,Ata M,Al Ali F,Khan T,Spaan AN,Dalgard CL,Bonfanti P,Biondi A,Tubiana S,Burdet C,Nussbaum R,Kahn-Kirby A,Snow AL,Bustamante J,Puel A,Boisson-Dupuis S,Zhang SY,Béziat V,Lifton RP,Bastard P,Notarangelo LD,Abel L,Su HC,Jouanguy E,Amara A,Soumelis V,Cobat A,Zhang Q,Casanova JL
MHCD2030 was used in Flow Cytometry to report very rare, biochemically deleterious X-linked TLR7 variants in 16 unrelated male individuals with unexplained critical COVID-19 pneumonia.
Thu Aug 19 00:00:00 EDT 2021
Mucosal-associated invariant T cell responses differ by sex in COVID-19.
Med (New York, N.Y.)
Yu C,Littleton S,Giroux NS,Mathew R,Ding S,Kalnitsky J,Yang Y,Petzold E,Chung HA,Rivera GO,Rotstein T,Xi R,Ko ER,Tsalik EL,Sempowski GD,Denny TN,Burke TW,McClain MT,Woods CW,Shen X,Saban DR
MHCD2030 was used in Flow Cytometry to reveal a pronounced reduction of circulating mucosal-associated invariant T (MAIT) cells in infected females.
Fri Jun 11 00:00:00 EDT 2021
Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies.
JCI insight
Shah HB,Smith K,Scott EJ,Larabee JL,James JA,Ballard JD,Lang ML
MHCD2030 was used in Flow Cytometry to study memory B cell function following C. difficile infection.
Thu Aug 20 00:00:00 EDT 2020
Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies.
JCI insight
Shah HB,Smith K,Scott EJ,Larabee JL,James JA,Ballard JD,Lang ML
MHCD2030 was used in Flow Cytometry to study memory B cell function following C. difficile infection.
Thu Aug 20 00:00:00 EDT 2020
T Cell Repertoire Maturation Induced by Persistent and Latent Viral Infection Is Insufficient to Induce Costimulation Blockade Resistant Organ Allograft Rejection in Mice.
Frontiers in immunology
Espinosa JR,Mou D,Adams BW,DiBernardo LR,MacDonald AL,McRae M,Miller AN,Song M,Stempora LL,Wang J,Iwakoshi NN,Kirk AD
MHCD2030 was used in Flow cytometry/Cell sorting to investigate whether costimulation blockade-resistant rejection would emerge in a model of virus-induced memory differentiation designed to more closely mimic clinical conditions of organ allograft rejection.
Wed Nov 20 00:00:00 EST 2019
LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation.
Journal of immunology (Baltimore, Md. : 1950)
Llibre A,López-Macías C,Marafioti T,Mehta H,Partridge A,Kanzig C,Rivellese F,Galson JD,Walker LJ,Milne P,Phillips RE,Kelly DF,Freeman GJ,El Shikh ME,Klenerman P,Willberg CB
MHCD2030 was used in Flow cytometry/Cell sorting to study the role of LLT1-CD161 interactions in B cell maturation within human germinal centres.
Tue Mar 01 00:00:00 EST 2016
Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients.
Journal of immunology (Baltimore, Md. : 1950)
Neumann L,Mueller M,Moos V,Heller F,Meyer TF,Loddenkemper C,Bojarski C,Fehlings M,Doerner T,Allers K,Aebischer T,Ignatius R,Schneider T
MHCD2030 was used in flow cytometry to report that IgA-producing plasma cells are a major source of inducible NO synthase in Helicobacter pylori-infected patients
Thu Sep 01 00:00:00 EDT 2016
In vitro and in vivo imaging of initial B-T-cell interactions in the setting of B-cell based cancer immunotherapy.
Oncoimmunology
Gonzalez NK,Wennhold K,Balkow S,Kondo E,Bölck B,Weber T,Garcia-Marquez M,Grabbe S,Bloch W,von Bergwelt-Baildon M,Shimabukuro-Vornhagen A
MHCD2030 was used in flow cytometry to study B cells migration in vivo
Tue Sep 01 00:00:00 EDT 2015
Brefeldin A, but not monensin, enables flow cytometric detection of interleukin-4 within peripheral T cells responding to ex vivo stimulation with Chlamydia trachomatis.
Journal of immunological methods
Vicetti Miguel RD,Maryak SA,Cherpes TL
MHCD2030 was used in Flow cytometry/Cell sorting to compare the ability of brefeldin A and monensin to concurrently trap 4 cytokines within peripheral blood mononuclear cells.
Wed Oct 31 00:00:00 EDT 2012
