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CD200 Antibody (MA5-23575) in Flow
Flow cytometry of CD200 in Th17 differentiated human peripheral blood mononuclear cells (PBMCs). Samples were incubated in CD200 monoclonal antibody (Product # MA5-23575) followed by Mouse Anti-Human CD3ε PE-conjugated Monoclonal Antibody. Quadrant markers were set based on control antibody staining.
Product Details
MA5-23575
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
325516
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD200 Gln31-Gly232
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
Buffered saline solution with BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608819
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant mouse CD200 is observed.
Target Information
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antigen identified by monoclonal antibody MRC OX-2; CD200; CD200 antigen; OX-2 membrane glycoprotein
Gene Aliases: CD200; MOX1; MOX2; MRC; My033; OX-2
UniProt ID: (Human) P41217
Entrez Gene ID: (Human) 4345
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