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Invitrogen
CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01), FITC
FIGURE: 1 / 2
CD264 (TRAIL-R4) Antibody (MA1-10163) in Flow
Separation of cells stained using anti-human CD264 (TRAIL-R4-01) FITC Monoclonal antibody (Product # MA1-10163) (concentration in sample 1 µg/mL, red-filled) from cells stained using mouse IgG1 isotype control (MOPC-21) FITC antibody (concentration in sample 1 µg/mL, black-dashed) in flow cytometry analysis (surface staining) of CD264 transfected HEK-293 cell suspension.
Product Details
MA1-10163
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
TRAIL-R4-01
Immunogen
TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11155412
Product Specific Information
This antibody reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
Target Information
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD264; DcR2; Decoy receptor 2; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Gene Aliases: CD264; DCR2; TNFRSF10D; TRAIL-R4; TRAILR4; TRUNDD; UNQ251/PRO288
UniProt ID: (Human) Q9UBN6
Entrez Gene ID: (Human) 8793
inflammatory response
immune response
signal transduction
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
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