Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01)
FIGURE: 1 / 1
CD264 (TRAIL-R4) Antibody (MA1-19730) in Flow
Separation of CD264 transfected HEK-293 cells (red-filled) from HEK-293 nontransfected cells (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD264 (TRAIL-R4-01) purified Monoclonal antibody (Product # MA1-19730) (concentration in sample 0.33 µg/mL) GAM APC.
Product Details
MA1-19730
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
TRAIL-R4-01
Immunogen
TRAIL-R4 (aa 1-210) - hIgGhc fusion protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
4° C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1091006
Product Specific Information
This antibody reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
Target Information
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CD264; DcR2; Decoy receptor 2; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Gene Aliases: CD264; DCR2; TNFRSF10D; TRAIL-R4; TRAILR4; TRUNDD; UNQ251/PRO288
UniProt ID: (Human) Q9UBN6
Entrez Gene ID: (Human) 8793
inflammatory response
immune response
signal transduction
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support