Product References
Immuno-PET Imaging of Tumour PD-L1 Expression in Glioblastoma.
Cancers
Sharma G,Braga MC,Da Pieve C,Szopa W,Starzetz T,Plate KH,Kaspera W,Kramer-Marek G
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri Jun 09 00:00:00 EDT 2023
The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1.
Cells
Erlichman N,Meshel T,Baram T,Abu Raiya A,Horvitz T,Ben-Yaakov H,Ben-Baruch A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Sat Sep 23 00:00:00 EDT 2023
NKp44-Derived Peptide Used in Combination Stimulates Antineoplastic Efficacy of Targeted Therapeutic Drugs.
International journal of molecular sciences
Iraqi M,Bolel P,Sarkar R,Bhattacharya B,Abu Ahmad M,Edri A,Roisman LC,Elkabets M,Shalata W,Peled N,Porgador A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Nov 14 00:00:00 EST 2022
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2.
Frontiers in immunology
Lellahi SM,Azeem W,Hua Y,Gabriel B,Paulsen Rye K,Reikvam H,Kalland KH
25-5983-42 was used in Flow cytometry/Cell sorting to suggest that GM-CSF, IL-4 and Flt3-L and combinations might be beneficial for DC viability and function in vitro.
Wed Feb 01 00:00:00 EST 2023
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2.
Frontiers in immunology
Lellahi SM,Azeem W,Hua Y,Gabriel B,Paulsen Rye K,Reikvam H,Kalland KH
25-5983-42 was used in Flow cytometry/Cell sorting to suggest that GM-CSF, IL-4 and Flt3-L and combinations might be beneficial for DC viability and function in vitro.
Wed Feb 01 00:00:00 EST 2023
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
Journal for immunotherapy of cancer
Bajor M,Graczyk-Jarzynka A,Marhelava K,Burdzinska A,Muchowicz A,Goral A,Zhylko A,Soroczynska K,Retecki K,Krawczyk M,Klopotowska M,Pilch Z,Paczek L,Malmberg KJ,Wälchli S,Winiarska M,Zagozdzon R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Ruxolitinib reverses checkpoint inhibition by reducing programmed cell death ligand-1 (PD-L1) expression and increases anti-tumour effects of T cells in multiple myeloma.
British journal of haematology
Chen H,Li M,Ng N,Yu E,Bujarski S,Yin Z,Wen M,Hekmati T,Field D,Wang J,Nassir I,Yu J,Huang J,Daniely D,Wang CS,Xu N,Spektor TM,Berenson JR
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages.
Journal of inflammation research
Lai CY,Tseng PC,Chen CL,Satria RD,Wang YT,Lin CF
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Apr 27 00:00:00 EDT 2022
Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition.
Frontiers in endocrinology
Castro-Gutierrez R,Alkanani A,Mathews CE,Michels A,Russ HA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
IL-27 Mediates PD-L1 Expression and Release by Human Mesothelioma Cells.
Cancers
Carbotti G,Dozin B,Martini S,Giordano C,Scordamaglia F,Croce M,Filaci G,Ferrini S,Fabbi M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Aug 09 00:00:00 EDT 2021
Protocol for high-throughput compound screening using flow cytometry in THP-1 cells.
STAR protocols
Spangenberg SH,Zavareh RB,Lairson LL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Science immunology
Asano T,Boisson B,Onodi F,Matuozzo D,Moncada-Velez M,Maglorius Renkilaraj MRL,Zhang P,Meertens L,Bolze A,Materna M,Korniotis S,Gervais A,Talouarn E,Bigio B,Seeleuthner Y,Bilguvar K,Zhang Y,Neehus AL,Ogishi M,Pelham SJ,Le Voyer T,Rosain J,Philippot Q,Soler-Palacín P,Colobran R,Martin-Nalda A,Rivière JG,Tandjaoui-Lambiotte Y,Chaïbi K,Shahrooei M,Darazam IA,Olyaei NA,Mansouri D,Hatipoğlu N,Palabiyik F,Ozcelik T,Novelli G,Novelli A,Casari G,Aiuti A,Carrera P,Bondesan S,Barzaghi F,Rovere-Querini P,Tresoldi C,Franco JL,Rojas J,Reyes LF,Bustos IG,Arias AA,Morelle G,Christèle K,Troya J,Planas-Serra L,Schlüter A,Gut M,Pujol A,Allende LM,Rodriguez-Gallego C,Flores C,Cabrera-Marante O,Pleguezuelo DE,de Diego RP,Keles S,Aytekin G,Akcan OM,Bryceson YT,Bergman P,Brodin P,Smole D,Smith CIE,Norlin AC,Campbell TM,Covill LE,Hammarström L,Pan-Hammarström Q,Abolhassani H,Mane S,Marr N,Ata M,Al Ali F,Khan T,Spaan AN,Dalgard CL,Bonfanti P,Biondi A,Tubiana S,Burdet C,Nussbaum R,Kahn-Kirby A,Snow AL,Bustamante J,Puel A,Boisson-Dupuis S,Zhang SY,Béziat V,Lifton RP,Bastard P,Notarangelo LD,Abel L,Su HC,Jouanguy E,Amara A,Soumelis V,Cobat A,Zhang Q,Casanova JL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Aug 19 00:00:00 EDT 2021
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Nature
Heinz LX,Lee J,Kapoor U,Kartnig F,Sedlyarov V,Papakostas K,César-Razquin A,Essletzbichler P,Goldmann U,Stefanovic A,Bigenzahn JW,Scorzoni S,Pizzagalli MD,Bensimon A,Müller AC,King FJ,Li J,Girardi E,Mbow ML,Whitehurst CE,Rebsamen M,Superti-Furga G
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion.
The Journal of experimental medicine
Du L,Lee JH,Jiang H,Wang C,Wang S,Zheng Z,Shao F,Xu D,Xia Y,Li J,Zheng Y,Qian X,Li X,Kim HR,Xing D,Liu P,Lu Z,Lyu J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2020
Protein kinase D3 regulates the expression of the immunosuppressive protein, PD‑L1, through STAT1/STAT3 signaling.
International journal of oncology
Cui B,Chen J,Luo M,Wang L,Chen H,Kang Y,Wang J,Zhou X,Feng Y,Zhang P
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis.
Nature communications
Oulès B,Philippeos C,Segal J,Tihy M,Vietri Rudan M,Cujba AM,Grange PA,Quist S,Natsuga K,Deschamps L,Dupin N,Donati G,Watt FM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2020
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis.
Nature communications
Oulès B,Philippeos C,Segal J,Tihy M,Vietri Rudan M,Cujba AM,Grange PA,Quist S,Natsuga K,Deschamps L,Dupin N,Donati G,Watt FM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2020
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Lentiviral delivery of combinatorial CAR/CRISPRi circuit into human primary T cells is enhanced by TBK1/IKKɛ complex inhibitor BX795.
Journal of translational medicine
Li L,Gao Y,Srivastava R,Wang W,Xiong Q,Fang Z,Pelayo A,Denson C,Goswami A,Harari-Steinfeld R,Yang Z,Weng L,Qi LS,Marincola FM
25-5983-42 was used in Flow Cytometry to show that this approach might also be helpful for other T cell therapy products that need delivery of complicated platform via large payload lentiviral vectors.
Wed Sep 23 00:00:00 EDT 2020
Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.
Cell
Poggio M,Hu T,Pai CC,Chu B,Belair CD,Chang A,Montabana E,Lang UE,Fu Q,Fong L,Blelloch R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Apr 04 00:00:00 EDT 2019
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.
Immunity
Zhao Y,Lee CK,Lin CH,Gassen RB,Xu X,Huang Z,Xiao C,Bonorino C,Lu LF,Bui JD,Hui E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Dec 17 00:00:00 EST 2019
Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.
International journal of oncology
Nakayama Y,Mimura K,Tamaki T,Shiraishi K,Kua LF,Koh V,Ohmori M,Kimura A,Inoue S,Okayama H,Suzuki Y,Nakazawa T,Ichikawa D,Kono K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Cell reports
Celis-Gutierrez J,Blattmann P,Zhai Y,Jarmuzynski N,Ruminski K,Grégoire C,Ounoughene Y,Fiore F,Aebersold R,Roncagalli R,Gstaiger M,Malissen B
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
High PD-L1 Expression Predicts for Worse Outcome of Leukemia Patients with Concomitant NPM1 and FLT3 Mutations.
International journal of molecular sciences
Brodská B,Otevřelová P,Šálek C,Fuchs O,Gašová Z,Kuželová K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Jun 10 00:00:00 EDT 2019
High PD-L1 Expression Predicts for Worse Outcome of Leukemia Patients with Concomitant NPM1 and FLT3 Mutations.
International journal of molecular sciences
Brodská B,Otevřelová P,Šálek C,Fuchs O,Gašová Z,Kuželová K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Jun 10 00:00:00 EDT 2019
CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?
Molecules (Basel, Switzerland)
Musielak B,Kocik J,Skalniak L,Magiera-Mularz K,Sala D,Czub M,Stec M,Siedlar M,Holak TA,Plewka J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2.
Frontiers in immunology
Baruah P,Bullenkamp J,Wilson POG,Lee M,Kaski JC,Dumitriu IE
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
Cell
Dijkstra KK,Cattaneo CM,Weeber F,Chalabi M,van de Haar J,Fanchi LF,Slagter M,van der Velden DL,Kaing S,Kelderman S,van Rooij N,van Leerdam ME,Depla A,Smit EF,Hartemink KJ,de Groot R,Wolkers MC,Sachs N,Snaebjornsson P,Monkhorst K,Haanen J,Clevers H,Schumacher TN,Voest EE
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.
Circulation research
Tamosiuniene R,Manouvakhova O,Mesange P,Saito T,Qian J,Sanyal M,Lin YC,Nguyen LP,Luria A,Tu AB,Sante JM,Rabinovitch M,Fitzgerald DJ,Graham BB,Habtezion A,Voelkel NF,Aurelian L,Nicolls MR
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri Jun 08 00:00:00 EDT 2018
Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.
The Journal of investigative dermatology
Philippeos C,Telerman SB,Oulès B,Pisco AO,Shaw TJ,Elgueta R,Lombardi G,Driskell RR,Soldin M,Lynch MD,Watt FM
25-5983 was used in Flow cytometry/Cell sorting to suggest that ex vivo expansion or in vivo ablation of specific fibroblast subpopulations may have therapeutic applications in wound healing and diseases characterized by excessive fibrosis.
Sun Apr 01 00:00:00 EDT 2018
Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.
Pediatric blood & cancer
Witt DA,Donson AM,Amani V,Moreira DC,Sanford B,Hoffman LM,Handler MH,Levy JMM,Jones KL,Nellan A,Foreman NK,Griesinger AM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma.
Frontiers in pharmacology
Guo X,Jiang H,Shi B,Zhou M,Zhang H,Shi Z,Du G,Luo H,Wu X,Wang Y,Sun R,Li Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Sep 28 00:00:00 EDT 2023
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.
PLoS neglected tropical diseases
Narasimhan PB,Akabas L,Tariq S,Huda N,Bennuru S,Sabzevari H,Hofmeister R,Nutman TB,Tolouei Semnani R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
PD-L1 expression in medulloblastoma: an evaluation by subgroup.
Oncotarget
Martin AM,Nirschl CJ,Polanczyk MJ,Bell WR,Nirschl TR,Harris-Bookman S,Phallen J,Hicks J,Martinez D,Ogurtsova A,Xu H,Sullivan LM,Meeker AK,Raabe EH,Cohen KJ,Eberhart CG,Burger PC,Santi M,Taube JM,Pardoll DM,Drake CG,Lim M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Apr 10 00:00:00 EDT 2018
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse.
Journal of hematology & oncology
Zheng B,Ren T,Huang Y,Sun K,Wang S,Bao X,Liu K,Guo W
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Feb 06 00:00:00 EST 2018
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Journal of experimental & clinical cancer research : CR
Xu L,Zhang Y,Tian K,Chen X,Zhang R,Mu X,Wu Y,Wang D,Wang S,Liu F,Wang T,Zhang J,Liu S,Zhang Y,Tu C,Liu H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Oct 29 00:00:00 EDT 2018
Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.
Cell reports
Zhao Y,Harrison DL,Song Y,Ji J,Huang J,Hui E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Jul 10 00:00:00 EDT 2018
Challenging PD-L1 expressing cytotoxic T cells as a predictor for response to immunotherapy in melanoma.
Nature communications
Brochez L,Meireson A,Chevolet I,Sundahl N,Ost P,Kruse V
25-5983 was used in Flow cytometry/Cell sorting to study the association of PD-L1-expressing cytotoxic T cells with an altered immune climate and a negative impact on disease outcome in melanoma patients independent of treatment.
Thu Jul 26 00:00:00 EDT 2018
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
Coelho MA,de Carné Trécesson S,Rana S,Zecchin D,Moore C,Molina-Arcas M,East P,Spencer-Dene B,Nye E,Barnouin K,Snijders AP,Lai WS,Blackshear PJ,Downward J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Dec 19 00:00:00 EST 2017
Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro.
Molecular therapy. Nucleic acids
Lin AH,Twitty CG,Burnett R,Hofacre A,Mitchell LA,Espinoza FL,Gruber HE,Jolly DJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri Mar 17 00:00:00 EDT 2017
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression.
Stem cells (Dayton, Ohio)
Davies LC,Heldring N,Kadri N,Le Blanc K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting.
The American journal of pathology
Fromm JR,Thomas A,Wood BL
25598342 was used in flow cytometry to document and describe lymphocyte predominant cells from lymph nodes involved in nodular lymphocyte predominant Hodgkin lymphoma
Wed Feb 01 00:00:00 EST 2017
Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.
Oncoimmunology
Layer JP,Kronmüller MT,Quast T,van den Boorn-Konijnenberg D,Effern M,Hinze D,Althoff K,Schramm A,Westermann F,Peifer M,Hartmann G,Tüting T,Kolanus W,Fischer M,Schulte J,Hölzel M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
PD-L1/PD-1 expression and tumor-infiltrating lymphocytes in conjunctival melanoma.
Oncotarget
Cao J,Brouwer NJ,Richards KE,Marinkovic M,van Duinen S,Hurkmans D,Verdegaal EME,Jordanova ES,Jager MJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
CD3xPDL1 bi-specific T cell engager (BiTE) simultaneously activates T cells and NKT cells, kills PDL1+ tumor cells, and extends the survival of tumor-bearing humanized mice.
Oncotarget
Horn LA,Ciavattone NG,Atkinson R,Woldergerima N,Wolf J,Clements VK,Sinha P,Poudel M,Ostrand-Rosenberg S
25-5983 was used in Flow cytometry/Cell sorting to suggest that the CD3xPDL1 BiTE may be efficacious for patients with PDL1(+) solid tumors, in combination with other immunotherapies that do not specifically neutralize PD1 pathway-mediated immune suppression.
Tue Aug 29 00:00:00 EDT 2017
CD3xPDL1 bi-specific T cell engager (BiTE) simultaneously activates T cells and NKT cells, kills PDL1+ tumor cells, and extends the survival of tumor-bearing humanized mice.
Oncotarget
Horn LA,Ciavattone NG,Atkinson R,Woldergerima N,Wolf J,Clements VK,Sinha P,Poudel M,Ostrand-Rosenberg S
25-5983 was used in Flow cytometry/Cell sorting to suggest that the CD3xPDL1 BiTE may be efficacious for patients with PDL1(+) solid tumors, in combination with other immunotherapies that do not specifically neutralize PD1 pathway-mediated immune suppression.
Tue Aug 29 00:00:00 EDT 2017
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Expression of programmed death 1 ligand 1 on periodontal tissue cells as a possible protective feedback mechanism against periodontal tissue destruction.
Molecular medicine reports
Zhang J,Wang CM,Zhang P,Wang X,Chen J,Yang J,Lu W,Zhou W,Yuan W,Feng Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.
Cancer immunology research
Severson JJ,Serracino HS,Mateescu V,Raeburn CD,McIntyre RC,Sams SB,Haugen BR,French JD
25-5983 was used in Flow cytometry/Cell sorting to determine that the release of PD-1 and Tim-3, and the inhibition of Tregs, may encourage tumour elimination in metastatic differentiated thyroid cancer.
Mon Jun 01 00:00:00 EDT 2015
T-helper 17 cell polarization in pulmonary arterial hypertension.
Chest
Hautefort A,Girerd B,Montani D,Cohen-Kaminsky S,Price L,Lambrecht BN,Humbert M,Perros F
25-5983 was used in Flow cytometry/Cell sorting to study T helper 17 cell immune polarization in patients with pulmonary arterial hypertension.
Mon Jun 01 00:00:00 EDT 2015
STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells.
Immunology and cell biology
Okada S,Han S,Patel ES,Yang LJ,Chang LJ
25-5983 was used in Flow cytometry/Cell sorting to investigate the differential cytokine-mediated signalling in DCs, showing that STAT3 signalling contributes to the high effector activities of interleukin-15-derived DCs.
Wed Feb 17 00:00:00 EST 2016
Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance.
Prostate cancer and prostatic diseases
Martin AM,Nirschl TR,Nirschl CJ,Francica BJ,Kochel CM,van Bokhoven A,Meeker AK,Lucia MS,Anders RA,DeMarzo AM,Drake CG
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
IL-27 induces the expression of IDO and PD-L1 in human cancer cells.
Oncotarget
Carbotti G,Barisione G,Airoldi I,Mezzanzanica D,Bagnoli M,Ferrero S,Petretto A,Fabbi M,Ferrini S
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
Helicobacter pylori cag pathogenicity island's role in B7-H1 induction and immune evasion.
PloS one
Lina TT,Alzahrani S,House J,Yamaoka Y,Sharpe AH,Rampy BA,Pinchuk IV,Reyes VE
25-5983 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms and functional relevance of B7-H1 induction by Helicobacter pylori infection to chronic infection.
Thu Mar 03 00:00:00 EST 2016
Characterization of the in vivo immune network of IDO, tryptophan metabolism, PD-L1, and CTLA-4 in circulating immune cells in melanoma.
Oncoimmunology
Chevolet I,Speeckaert R,Schreuer M,Neyns B,Krysko O,Bachert C,Hennart B,Allorge D,van Geel N,Van Gele M,Brochez L
25-5983 was used in Flow cytometry/Cell sorting to demonstrate that the expression of IDO, PD-L1, and CTLA-4 in the peripheral blood of melanoma patients is strongly interconnected.
Sun Mar 01 00:00:00 EST 2015
Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma.
Journal of translational medicine
Chevolet I,Speeckaert R,Schreuer M,Neyns B,Krysko O,Bachert C,Van Gele M,van Geel N,Brochez L
25-5983 was used in Flow cytometry/Cell sorting to investigate multiple immune cell types in a series of blood samples from melanoma patients with different stages of the disease.
Fri Jan 16 00:00:00 EST 2015
Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells.
Frontiers in immunology
Legat A,Speiser DE,Pircher H,Zehn D,Fuertes Marraco SA
25-5983 was used in Flow cytometry/Cell sorting to evaluate the direct relationship between inhibitory receptor expression and functionality in CD8 T cells.
Mon Jan 06 00:00:00 EST 2014
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.
Oncotarget
Wrangle J,Wang W,Koch A,Easwaran H,Mohammad HP,Vendetti F,Vancriekinge W,Demeyer T,Du Z,Parsana P,Rodgers K,Yen RW,Zahnow CA,Taube JM,Brahmer JR,Tykodi SS,Easton K,Carvajal RD,Jones PA,Laird PW,Weisenberger DJ,Tsai S,Juergens RA,Topalian SL,Rudin CM,Brock MV,Pardoll D,Baylin SB
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Phagocytosis, a potential mechanism for myeloid-derived suppressor cell regulation of CD8+ T cell function mediated through programmed cell death-1 and programmed cell death-1 ligand interaction.
Journal of immunology (Baltimore, Md. : 1950)
Kim YJ,Park SJ,Broxmeyer HE
25-5983 was used in Flow cytometry/Cell sorting to identify a potential mechanism by which IFN-γ-producing CD8(+) T cells are tolerised after type 1 immune responses to chronic virus or tumour.
Thu Sep 01 00:00:00 EDT 2011
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.
Blood
Benson DM,Bakan CE,Mishra A,Hofmeister CC,Efebera Y,Becknell B,Baiocchi RA,Zhang J,Yu J,Smith MK,Greenfield CN,Porcu P,Devine SM,Rotem-Yehudar R,Lozanski G,Byrd JC,Caligiuri MA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2010
PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950)
Fourcade J,Kudela P,Sun Z,Shen H,Land SR,Lenzner D,Guillaume P,Luescher IF,Sander C,Ferrone S,Kirkwood JM,Zarour HM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5983-42) in Flow Cytometry
Fri May 01 00:00:00 EDT 2009
Expression of B7-H1 in inflammatory renal tubular epithelial cells.
Nephron. Experimental nephrology
Chen Y,Zhang J,Li J,Zou L,Zhao T,Tang Y,Wu Y
Fri Apr 21 00:00:00 EDT 2006
Expression of B7-H1 in inflammatory renal tubular epithelial cells.
Nephron. Experimental nephrology
Chen Y,Zhang J,Li J,Zou L,Zhao T,Tang Y,Wu Y
Fri Apr 21 00:00:00 EDT 2006
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ohigashi Y,Sho M,Yamada Y,Tsurui Y,Hamada K,Ikeda N,Mizuno T,Yoriki R,Kashizuka H,Yane K,Tsushima F,Otsuki N,Yagita H,Azuma M,Nakajima Y
Fri Apr 15 00:00:00 EDT 2005