Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Purity is > 95% by SDS-PAGE.
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B7 homolog 2; B7 homologue 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; ICOS ligand; inducible T-cell co-stimulator ligand; LICOS; transmembrane protein B7-H2 ICOS ligand
Gene Aliases: AU044799; B7-H2; B7h; B7H2; B7RP-1; B7RP1; BG071784; CD275; GI50; GL50; GL50-B; ICOS-L; ICOSL; ICOSLG; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791
UniProt ID: (Human) O75144, (Mouse) Q9JHJ8
Entrez Gene ID: (Human) 23308, (Mouse) 50723, (Rat) 499415
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support