Product References
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
12-5889-42 was used in Flow cytometry/Cell sorting to report that human blood CD1c+ dendritic cells activated by GM-CSF (also known as CSF2) drive the differentiation of naive CD4+ T cells into Tfh1 cells.
Tue Nov 01 00:00:00 EDT 2022
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
12-5889-42 was used in Flow cytometry/Cell sorting to report that human blood CD1c+ dendritic cells activated by GM-CSF (also known as CSF2) drive the differentiation of naive CD4+ T cells into Tfh1 cells.
Tue Nov 01 00:00:00 EDT 2022
Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion.
eLife
Angulo G,Zeleznjak J,Martínez-Vicente P,Puñet-Ortiz J,Hengel H,Messerle M,Oxenius A,Jonjic S,Krmpotić A,Engel P,Angulo A
Published figure using CD275 (B7-H2) monoclonal antibody (Product # 12-5889-42) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2021
Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta.
Stem cell research & therapy
Ventura Ferreira MS,Bienert M,Müller K,Rath B,Goecke T,Opländer C,Braunschweig T,Mela P,Brümmendorf TH,Beier F,Neuss S
12-5889 was used in Western Blotting to study how besides SOX2 expression, no other pluripotency features were observed in early and late passages of CV-MSC.
Mon Feb 05 00:00:00 EST 2018
Targeting the Human T-Cell Inducible COStimulator Molecule with a Monoclonal Antibody Prevents Graft-vs-Host Disease and Preserves Graft vs Leukemia in a Xenograft Murine Model.
Frontiers in immunology
Burlion A,Brunel S,Petit NY,Olive D,Marodon G
12-5889 was used in Flow cytometry/Cell sorting to determine the role of monoclonal antibody to human ICOS in costimulatory signalling to human T cells.
Wed Nov 20 00:00:00 EST 2019
Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells--possible implications for the ICOS/ICOS-ligand axis in disease course and resolution.
Clinical and experimental immunology
Sakthivel P,Grunewald J,Eklund A,Bruder D,Wahlström J
Published figure using CD275 (B7-H2) monoclonal antibody (Product # 12-5889-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors.
Oncoimmunology
Pedroza-Gonzalez A,Zhou G,Vargas-Mendez E,Boor PP,Mancham S,Verhoef C,Polak WG,Grünhagen D,Pan Q,Janssen H,Garcia-Romo GS,Biermann K,Tjwa ET,IJzermans JN,Kwekkeboom J,Sprengers D
Published figure using CD275 (B7-H2) monoclonal antibody (Product # 12-5889-42) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
A novel subset of B7-H3+CD14+HLA-DR-/low myeloid-derived suppressor cells are associated with progression of human NSCLC.
Oncoimmunology
Zhang G,Huang H,Zhu Y,Yu G,Gao X,Xu Y,Liu C,Hou J,Zhang X
12-5889 was used in Flow cytometry/Cell sorting to assess the contribution of myeloid-derived suppressor cells to tumour progression and metastasis.
Sun Feb 01 00:00:00 EST 2015
Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity.
Nature communications
Willmann KL,Klaver S,Doğu F,Santos-Valente E,Garncarz W,Bilic I,Mace E,Salzer E,Conde CD,Sic H,Májek P,Banerjee PP,Vladimer GI,Haskoloğlu S,Bolkent MG,Küpesiz A,Condino-Neto A,Colinge J,Superti-Furga G,Pickl WF,van Zelm MC,Eibel H,Orange JS,Ikincioğulları A,Boztuğ K
12-5889 was used in Flow cytometry/Cell sorting to study the effect of a biallelic mutation in the gene encoding NF-κB-inducing kinase on immune cell populations.
Wed Nov 19 00:00:00 EST 2014
CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection.
Journal of immunology (Baltimore, Md. : 1950)
Lina TT,Pinchuk IV,House J,Yamaoka Y,Graham DY,Beswick EJ,Reyes VE
12-5889 was used in Flow cytometry/Cell sorting to investigate the impact of H.pylori CagA on the modulation of the expression of the T cell costimulator B7-H2 by gastric epithelial cells.
Tue Oct 01 00:00:00 EDT 2013
Novel role of plasmacytoid dendritic cells in humans: induction of interleukin-10-producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy.
Arthritis and rheumatism
Kavousanaki M,Makrigiannakis A,Boumpas D,Verginis P
12-5889 was used in Flow cytometry/Cell sorting to explore the contribution of dendritic cells to the development of regulatory T cells in a human autoimmune disease setting.
Fri Jan 01 00:00:00 EST 2010
Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues.
Scandinavian journal of immunology
Youngnak-Piboonratanakit P,Tsushima F,Otsuki N,Igarashi H,Omura K,Azuma M
Wed Mar 01 00:00:00 EST 2006
Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues.
Scandinavian journal of immunology
Youngnak-Piboonratanakit P,Tsushima F,Otsuki N,Igarashi H,Omura K,Azuma M
Wed Mar 01 00:00:00 EST 2006
Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues.
Scandinavian journal of immunology
Youngnak-Piboonratanakit P,Tsushima F,Otsuki N,Igarashi H,Omura K,Azuma M
Wed Mar 01 00:00:00 EST 2006
Expression and function of inducible costimulator on peripheral blood T cells in patients with systemic lupus erythematosus.
Rheumatology (Oxford, England)
Yang JH,Zhang J,Cai Q,Zhao DB,Wang J,Guo PE,Liu L,Han XH,Shen Q
12-5889 was used in Flow cytometry/Cell sorting to show that the abnormality of ICOS costimulation in SLE patients may play an immunopathological role in pathogenesis.
Sat Oct 01 00:00:00 EDT 2005