Product References
Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma.
The Journal of clinical investigation
Huuhtanen J,Kasanen H,Peltola K,Lönnberg T,Glumoff V,Brück O,Dufva O,Peltonen K,Vikkula J,Jokinen E,Ilander M,Lee MH,Mäkelä S,Nyakas M,Li B,Hernberg M,Bono P,Lähdesmäki H,Kreutzman A,Mustjoki S
25-9948-42 was used in Flow cytometry/Cell sorting to show that anti-LAG3+anti-PD1 therapy has profound effects on NK cells and Tregs in addition to CD8+ T cells.
Wed Mar 15 00:00:00 EDT 2023
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.
Cell
Rodda LB,Netland J,Shehata L,Pruner KB,Morawski PA,Thouvenel CD,Takehara KK,Eggenberger J,Hemann EA,Waterman HR,Fahning ML,Chen Y,Hale M,Rathe J,Stokes C,Wrenn S,Fiala B,Carter L,Hamerman JA,King NP,Gale M,Campbell DJ,Rawlings DJ,Pepper M
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Thu Jan 07 00:00:00 EST 2021
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
25-9948-42 was used in Flow Cytometry to elucidate the molecular mechanisms regulating T follicular helper cells.
Thu Apr 01 00:00:00 EDT 2021
Immunological status of peripheral blood is associated with prognosis in patients with bone and soft-tissue sarcoma.
Oncology letters
Kim Y,Kobayashi E,Suehara Y,Ito A,Kubota D,Tanzawa Y,Endo M,Nakatani F,Nakatsura T,Kawai A,Kaneko K,Kitano S
25-9948 was used in Flow cytometry/Cell sorting to suggest that the immune status of peripheral blood was associated with the prognosis in patients with sarcoma, as previously reported in patients with other cancer types.
Mon Mar 01 00:00:00 EST 2021
Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans.
eLife
Hill DL,Whyte CE,Innocentin S,Lee JL,Dooley J,Wang J,James EA,Lee JC,Kwok WW,Zand MS,Liston A,Carr EJ,Linterman MA
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Tue Nov 02 00:00:00 EDT 2021
Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors.
Scientific reports
Dart SJ,Cook AM,Millward MJ,McDonnell AM,Chin WL,Hakeem MU,Meniawy TM,Bowyer SE
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Wed Jul 28 00:00:00 EDT 2021
IL-21-Deficient T Follicular Helper Cells Support B Cell Responses Through IL-27 in Patients With Chronic Hepatitis B.
Frontiers in immunology
Khanam A,Ayithan N,Tang L,Poonia B,Kottilil S
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Wed Jun 16 00:00:00 EDT 2021
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.
The Journal of experimental medicine
Hill DL,Pierson W,Bolland DJ,Mkindi C,Carr EJ,Wang J,Houard S,Wingett SW,Audran R,Wallin EF,Jongo SA,Kamaka K,Zand M,Spertini F,Daubenberger C,Corcoran AE,Linterman MA
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Mon Aug 05 00:00:00 EDT 2019
Ipilimumab plus Lenalidomide after Allogeneic and Autologous Stem Cell Transplantation for Patients with Lymphoid Malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Khouri IF,Fernandez Curbelo I,Turturro F,Jabbour EJ,Milton DR,Bassett RL,Vence LM,Allison JP,Gulbis AM,Sharma P
25-9948 was used in Flow cytometry/Cell sorting to hypothesize that antitumor-cell responses could be enhanced by the addition of lenalidomide to the cytotoxic T-lymphocyte-associated protein 4 inhibitor ipilimumab.
Thu Mar 01 00:00:00 EST 2018
Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile.
Cancer immunology research
Querfeld C,Leung S,Myskowski PL,Curran SA,Goldman DA,Heller G,Wu X,Kil SH,Sharma S,Finn KJ,Horwitz S,Moskowitz A,Mehrara B,Rosen ST,Halpern AC,Young JW
25-9948 was used in Flow cytometry/Cell sorting to identify the antigens driving T-cell exhaustion and the evaluation of immune checkpoint inhibition to reverse T-cell exhaustion earlier in treatment of cutaneous T-cell lymphoma.
Wed Aug 01 00:00:00 EDT 2018
Distribution of circulating follicular helper T cells and expression of interleukin-21 and chemokine C-X-C ligand 13 in gastric cancer.
Oncology letters
Meng X,Yu X,Dong Q,Xu X,Li J,Xu Q,Ma J,Zhou C
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Dysregulated ICOS+ proinflammatory and suppressive regulatory T cells in patients with rheumatoid arthritis.
Experimental and therapeutic medicine
Wang HX,Kang X,Chu S,Li H,Li X,Yin X,Qiu YR,Lai W
25-9948-42 was used in Flow cytometry/Cell sorting to suggest that ICOS+ Tregs may perform inflammatory and inhibitory functions, and abnormal ICOS+ Tregs numbers and functions may contribute to the pathogenesis of RA.
Mon Oct 01 00:00:00 EDT 2018
Dysregulated ICOS+ proinflammatory and suppressive regulatory T cells in patients with rheumatoid arthritis.
Experimental and therapeutic medicine
Wang HX,Kang X,Chu S,Li H,Li X,Yin X,Qiu YR,Lai W
25-9948-42 was used in Flow cytometry/Cell sorting to suggest that ICOS+ Tregs may perform inflammatory and inhibitory functions, and abnormal ICOS+ Tregs numbers and functions may contribute to the pathogenesis of RA.
Mon Oct 01 00:00:00 EDT 2018
PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients.
Cancer cell
Naing A,Infante JR,Papadopoulos KP,Chan IH,Shen C,Ratti NP,Rojo B,Autio KA,Wong DJ,Patel MR,Ott PA,Falchook GS,Pant S,Hung A,Pekarek KL,Wu V,Adamow M,McCauley S,Mumm JB,Wong P,Van Vlasselaer P,Leveque J,Tannir NM,Oft M
25-9948-42 was used in Flow cytometry/Cell sorting to report that pegilodecakin induces hallmarks of CD8+ T cell immunity in cancer patients, including elevation of interferon-γ and GranzymeB, expansion and activation of intratumoral CD8+ T cells, and proliferation and expansion of LAG-3+ PD-1+ CD8+ T cells.
Mon Nov 12 00:00:00 EST 2018
Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique.
Nature protocols
Baxter AE,Niessl J,Fromentin R,Richard J,Porichis F,Massanella M,Brassard N,Alsahafi N,Routy JP,Finzi A,Chomont N,Kaufmann DE
25-9948 was used in Flow cytometry/Cell sorting to develop a protocol for flow cytometric identification of viral reservoirs.
Sun Oct 01 00:00:00 EDT 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells.
Haematologica
Scottà C,Fanelli G,Hoong SJ,Romano M,Lamperti EN,Sukthankar M,Guggino G,Fazekasova H,Ratnasothy K,Becker PD,Afzali B,Lechler RI,Lombardi G
25-9948 was used in Flow cytometry/Cell sorting to study the effect of immunosuppressive drugs on Treg cells.
Fri Jan 01 00:00:00 EST 2016
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD278 (ICOS) monoclonal antibody (Product # 25-9948-42) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
The immunosuppressive enzyme IL4I1 promotes FoxP3(+) regulatory T lymphocyte differentiation.
European journal of immunology
Cousin C,Aubatin A,Le Gouvello S,Apetoh L,Castellano F,Molinier-Frenkel V
25-9948 was used in Flow cytometry/Cell sorting to study the effect of IL4I1 on naive CD4+ T cell differentiation.
Mon Jun 01 00:00:00 EDT 2015
Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice.
Immunology and cell biology
Bedke T,Iannitti RG,De Luca A,Giovannini G,Fallarino F,Berges C,Latgé JP,Einsele H,Romani L,Topp MS
25-9948 was used in Flow cytometry/Cell sorting to suggest that Tr1 cells most likely play a distinct and complementary role to Foxp3+ regulatory T-cells in antifungal immune homeostasis,.
Mon Sep 01 00:00:00 EDT 2014
Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome.
Blood
Antonelli LR,Mahnke Y,Hodge JN,Porter BO,Barber DL,DerSimonian R,Greenwald JH,Roby G,Mican J,Sher A,Roederer M,Sereti I
25-9948 was used in Flow cytometry/Cell sorting to indicate that IRIS appears to be a predominantly CD4-mediated phenomenon.
Thu Nov 11 00:00:00 EST 2010
Inducible costimulator: a modulator of IFN-gamma production in human tuberculosis.
Journal of immunology (Baltimore, Md. : 1950)
Quiroga MF,Pasquinelli V,Martínez GJ,Jurado JO,Zorrilla LC,Musella RM,Abbate E,Sieling PA,García VE
Mon May 15 00:00:00 EDT 2006