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Product Details
PA5-68389
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic protein corresponding to residues near the C terminal of human CD300e.
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2692235
Product Specific Information
Predicted to react with Human samples.
Target Information
CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is down regulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD300 antigen like family member E; CD300 antigen-like family member E; CD300e; CD300e antigen; CLM-2; CMRF-35-like molecule-1; CMRF35-A5; CMRF35-like molecule 2; Immune receptor expressed on myeloid cells 2; IREM-2; PIgR-2; poly-Ig receptor 2; Polymeric immunoglobulin receptor 2
Gene Aliases: BC034097; CD300E; CD300LE; CLM-2; CLM2; CMRF35-A5; CMRF35A5; IREM-2; IREM2; PIgR-2; PIgR2; TREM5
UniProt ID: (Human) Q496F6, (Mouse) Q8K249
Entrez Gene ID: (Human) 342510, (Mouse) 217306
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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