Invitrogen

CD44v6 Monoclonal Antibody (9A4)

1 Published Figure

3 References

View all (19) CD44v6 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Published Figures (1)

CD44v6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 1

CD44v6 Antibody (MA1-81995) in IHC (P)

BMC gastroenterology 2014 - Figure 1 Visualization of CD24 and CD44 expression in gastric cancer cells by immunohistochemistry. CD24 (A) and CD44 (B) immunostaining in the membrane of gastric carcinoma cells.

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Product Details

MA1-81995

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

ELISA (ELISA)

Assay-dependent

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

9A4

Immunogen

GST-CD44v6 fusion protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

purified

Storage buffer

PBS

Contains

<0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_928369

Product Specific Information

Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections.

Rat anti Mouse CD44v6, clone 9A4 recognizes an epitope encoded by exon v6 on the variant portion of murine CD44.

Target Information

CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.

Journal of experimental & clinical cancer research : CR

Cigliano A,Zhang S,Ribback S,Steinmann S,Sini M,Ament CE,Utpatel K,Song X,Wang J,Pilo MG,Berger F,Wang H,Tao J,Li X,Pes GM,Mancarella S,Giannelli G,Dombrowski F,Evert M,Calvisi DF,Chen X,Evert K

MA1-81995 was used in ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to establish a novel iCCA mouse model and demonstrate the crucial role of overexpressed TAZ behind cholangiocarcinogenesis.

Fri Jun 03 00:00:00 EDT 2022

The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic β-Catenin to Induce Hepatoblastoma Development in Mice and Humans.

The American journal of pathology

Zhang S,Zhang J,Evert K,Li X,Liu P,Kiss A,Schaff Z,Ament C,Zhang Y,Serra M,Evert M,Chen N,Xu F,Chen X,Tao J,Calvisi DF,Cigliano A

MA1-81995 was used in Immunohistochemistry to identify TAZ as a crucial oncogene in HB development and progression.

Wed Jul 01 00:00:00 EDT 2020

CD44 but not CD24 expression is related to poor prognosis in non-cardia adenocarcinoma of the stomach.

BMC gastroenterology

Cao X,Cao D,Jin M,Jia Z,Kong F,Ma H,Wang Y,Jiang J

MA1-81995 was used in immunohistochemistry - paraffin section to assess CD44 and CD24 expression in patients with gastric cancer and to evaluate their prognostic values

Fri Sep 12 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: AL133330.1; CD44; CD44 antigen; CD44 splice variant; CD44 V6; CD44 var; CD44 variant; CD44v6; CD44var (v6); ECMR-III; ECMRIII; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; HUTCH-I; HUTCHI; Hyaluronate receptor; Ly-24; Lymphocyte antigen 24; MGC10468; MUTCH-I; PGP I; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I

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Gene Aliases: AU023126; AW121933; AW146109; Cd44; HERMES; Ly-24; Pgp-1

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UniProt ID: (Mouse) P15379

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Entrez Gene ID: (Mouse) 12505

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Function(s)

hyalurononglucosaminidase activity cytokine receptor activity epidermal growth factor receptor binding protein binding hyaluronic acid binding protein kinase binding cytokine binding phosphoprotein binding transmembrane signal receptor

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CD44v6 Monoclonal Antibody (9A4)

CD44v6 Antibody (MA1-81995) in IHC (P)

Product Details

MA1-81995

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

ELISA (ELISA)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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