Product References
Human serum albumin promotes self-renewal and expansion of umbilical cord blood CD34+ hematopoietic stem/progenitor cells.
Annals of translational medicine
Hua J,Jiao T,Qiao Y,Zhang S,Xiao T,Zhang Y,Yan J
12-0495-82 was used in Flow Cytometry to find that HSA was beneficial to maintaining CD34+ cell expansion and short-term colony formation in vitro and optimizing multilineage reconstitution in immunodeficient mice in vivo.
Tue Jan 31 00:00:00 EST 2023
Isolation and characterization mesenchymal stem cells from red panda (Ailurus fulgens styani) endometrium.
Conservation physiology
Wang DH,Wu XM,Chen JS,Cai ZG,An JH,Zhang MY,Li Y,Li FP,Hou R,Liu YL
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer.
Scientific reports
Le UQ,Chen N,Balasenthil S,Lurie E,Yang F,Liu S,Rubin L,Solis Soto LM,Raso MG,Batra H,Sahin AA,Wistuba II,Killary AM
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Nov 14 00:00:00 EST 2022
Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis.
Cell reports
Wei X,Zhang L,Zhang Y,Cooper C,Brewer C,Tsai CF,Wang YT,Glaz M,Wessells HB,Que J,Titus MA,Cirulli V,Glaser A,Liu T,Reder NP,Creighton CJ,Xin L
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Sep 06 00:00:00 EDT 2022
The Effect of Infant Gastric Digestion on Human Maternal Milk Cells.
Molecular nutrition & food research
Doerfler R,Melamed JR,Whitehead KA
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2022
ROR2 regulates self-renewal and maintenance of hair follicle stem cells.
Nature communications
Veltri A,Lang CMR,Cangiotti G,Chan CK,Lien WH
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2022
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression.
Nature communications
Li N,Liu Q,Han Y,Pei S,Cheng B,Xu J,Miao X,Pan Q,Wang H,Guo J,Wang X,Zhang G,Lian Y,Zhang W,Zang Y,Tan M,Li Q,Wang X,Xiao Y,Hu G,Jiang J,Huang H,Qin J
12-0495-82 was used in flow cytometry to show that ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, functions downstream of inflammation-induced IKKβ activation to shape the immunosuppressive tumor microenvironment (TME).
Sat Nov 26 00:00:00 EST 2022
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2.
Neoplasia (New York, N.Y.)
Feng D,Yan K,Liang H,Liang J,Wang W,Yu H,Zhou Y,Zhao W,Dong Z,Ling B
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
Generation and functional characterization of murine mammary organoids.
STAR protocols
Yip HYK,Papa A
12-0495-82 was used in Flow Cytometry to describe step-by-step experimental procedures for the successful establishment of murine mammary organoid lines isolated from mammary glands or mammary tumors driven by mutations in components of the PI3K pathway.
Fri Sep 17 00:00:00 EDT 2021
Generation and functional characterization of murine mammary organoids.
STAR protocols
Yip HYK,Papa A
12-0495-82 was used in Flow Cytometry to describe step-by-step experimental procedures for the successful establishment of murine mammary organoid lines isolated from mammary glands or mammary tumors driven by mutations in components of the PI3K pathway.
Fri Sep 17 00:00:00 EDT 2021
Developmental genetics of color pattern establishment in cats.
Nature communications
Kaelin CB,McGowan KA,Barsh GS
12-0495-82 was used in Functional assays to identify when, where, and how, during fetal development, felid color patterns are established.
Tue Sep 07 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
12-0495-82 was used in Flow Cytometry to determine the impact of vitamin D signaling on prostatic precancerous lesions.
Thu Jul 01 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
12-0495-82 was used in Flow Cytometry to determine the impact of vitamin D signaling on prostatic precancerous lesions.
Thu Jul 01 00:00:00 EDT 2021
Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells.
Cell
Shwartz Y,Gonzalez-Celeiro M,Chen CL,Pasolli HA,Sheu SH,Fan SM,Shamsi F,Assaad S,Lin ET,Zhang B,Tsai PC,He M,Tseng YH,Lin SJ,Hsu YC
12-0495-82 was used in Flow Cytometry to demonstrate sympathetic nerves can modulate stem cells through synapse-like connections and neurotransmitters to couple tissue production with demands.
Thu Aug 06 00:00:00 EDT 2020
Infiltrating Mast Cell-Mediated Stimulation of Estrogen Receptor Activity in Breast Cancer Cells Promotes the Luminal Phenotype.
Cancer research
Majorini MT,Cancila V,Rigoni A,Botti L,Dugo M,Triulzi T,De Cecco L,Fontanella E,Jachetti E,Tagliabue E,Chiodoni C,Tripodo C,Colombo MP,Lecis D
12-0495-82 was used in Flow Cytometry to support the notion that MCs influence the phenotype of breast cancer cells by stimulating a luminal phenotype and ultimately modifying the outcome of the disease.
Mon Jun 01 00:00:00 EDT 2020
A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.
Proceedings of the National Academy of Sciences of the United States of America
Wang L,Smith BA,Balanis NG,Tsai BL,Nguyen K,Cheng MW,Obusan MB,Esedebe FN,Patel SJ,Zhang H,Clark PM,Sisk AE,Said JW,Huang J,Graeber TG,Witte ON,Chin AI,Park JW
12-0495 was used in Flow cytometry/Cell sorting to reveal distinct molecular features of small cell carcinoma of the bladder and provide a transcriptional dataset and a preclinical model for further investigating SCCB biology.
Tue Jan 07 00:00:00 EST 2020
An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration.
Molecular biology of the cell
Su S,Begum S,Ezratty EJ
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.
Nature communications
Azazmeh N,Assouline B,Winter E,Ruppo S,Nevo Y,Maly A,Meir K,Witkiewicz AK,Cohen J,Rizou SV,Pikarsky E,Luxenburg C,Gorgoulis VG,Ben-Porath I
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Chemotherapeutic Stress Influences Epithelial-Mesenchymal Transition and Stemness in Cancer Stem Cells of Triple-Negative Breast Cancer.
International journal of molecular sciences
Li X,Strietz J,Bleilevens A,Stickeler E,Maurer J
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2020
Polyisocyanide Hydrogels as a Tunable Platform for Mammary Gland Organoid Formation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Tang C,Span PN,Rowan AE,Aalders TW,Schalken JA,Adema GJ,Kouwer PHJ,Zegers MMP,Ansems M
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow.
Nature communications
Riedel R,Addo R,Ferreira-Gomes M,Heinz GA,Heinrich F,Kummer J,Greiff V,Schulz D,Klaeden C,Cornelis R,Menzel U,Kröger S,Stervbo U,Köhler R,Haftmann C,Kühnel S,Lehmann K,Maschmeyer P,McGrath M,Naundorf S,Hahne S,Sercan-Alp Ö,Siracusa F,Stefanowski J,Weber M,Westendorf K,Zimmermann J,Hauser AE,Reddy ST,Durek P,Chang HD,Mashreghi MF,Radbruch A
12-0495 was used in Flow cytometry/Cell sorting to identify distinct populations of isotype-switched memory B lymphocytes of murine spleen and bone marrow.
Fri May 22 00:00:00 EDT 2020
Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow.
Nature communications
Riedel R,Addo R,Ferreira-Gomes M,Heinz GA,Heinrich F,Kummer J,Greiff V,Schulz D,Klaeden C,Cornelis R,Menzel U,Kröger S,Stervbo U,Köhler R,Haftmann C,Kühnel S,Lehmann K,Maschmeyer P,McGrath M,Naundorf S,Hahne S,Sercan-Alp Ö,Siracusa F,Stefanowski J,Weber M,Westendorf K,Zimmermann J,Hauser AE,Reddy ST,Durek P,Chang HD,Mashreghi MF,Radbruch A
12-0495 was used in Flow cytometry/Cell sorting to identify distinct populations of isotype-switched memory B lymphocytes of murine spleen and bone marrow.
Fri May 22 00:00:00 EDT 2020
Olfactomedin 4 mediation of prostate stem/progenitor-like cell proliferation and differentiation via MYC.
Scientific reports
Li H,Chaitankar V,Zhu J,Chin K,Liu W,Pirooznia M,Rodgers GP
12-0495-82 was used in Flow Cytometry to indicate that OLFM4 is co-expressed with multiple stem/progenitor cell marker genes in prostate epithelial cells and acts as a novel mediator in prostate stem/progenitor cell proliferation and differentiation.
Mon Dec 14 00:00:00 EST 2020
Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity.
Cell reports
Pervolarakis N,Nguyen QH,Williams J,Gong Y,Gutierrez G,Sun P,Jhutty D,Zheng GXY,Nemec CM,Dai X,Watanabe K,Kessenbrock K
12-0495-82 was used in Flow Cytometry to provide a resource to reveal cis/trans-regulatory elements associated with MEC identity and differentiation that will serve as a reference to determine how the chromatin accessibility landscape changes during breast cancer.
Tue Oct 20 00:00:00 EDT 2020
m6A RNA methylation impacts fate choices during skin morphogenesis.
eLife
Xi L,Carroll T,Matos I,Luo JD,Polak L,Pasolli HA,Jaffrey SR,Fuchs E
12-0495 was used in Flow cytometry/Cell sorting to study mouse skin embryogenesis to tackle m6A's functions and physiological importance.
Wed Aug 26 00:00:00 EDT 2020
Cytosine-5 RNA methylation links protein synthesis to cell metabolism.
PLoS biology
Gkatza NA,Castro C,Harvey RF,Heiß M,Popis MC,Blanco S,Bornelöv S,Sajini AA,Gleeson JG,Griffin JL,West JA,Kellner S,Willis AE,Dietmann S,Frye M
12-0495 was used in Flow cytometry/Cell sorting to study whether changes in tRNA methylation profiles are sufficient to specify cellular metabolic states and efficiently adapt protein synthesis rates to cell stress.
Sat Jun 01 00:00:00 EDT 2019
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Disease models & mechanisms
Pfefferle AD,Darr DB,Calhoun BC,Mott KR,Rosen JM,Perou CM
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Fri Jul 05 00:00:00 EDT 2019
A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model.
Molecular carcinogenesis
Fan X,Bjerke GA,Riemondy K,Wang L,Yi R
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties.
Cells
Rémy M,Ferraro F,Le Salver P,Rey S,Genot E,Djavaheri-Mergny M,Thébaud N,Boiziau C,Boeuf H
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Thu Nov 21 00:00:00 EST 2019
Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro.
Nature communications
Feldman A,Mukha D,Maor II,Sedov E,Koren E,Yosefzon Y,Shlomi T,Fuchs Y
12-0495-82 was used in Flow cytometry/Cell sorting to demonstrate that single Blimp1+ cells have the potential to generate SG organoids in vitro.
Tue May 28 00:00:00 EDT 2019
Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells.
Cell reports
Wang K,Guzman AK,Yan Z,Zhang S,Hu MY,Hamaneh MB,Yu YK,Tolu S,Zhang J,Kanavy HE,Ye K,Bartholdy B,Bouhassira EE
12-0495-82 was used in Flow Cytometry to suggest LT-HSCs may become the preferred cell source for the production of clinical-grade iPSCs.
Tue Mar 05 00:00:00 EST 2019
Early lineage segregation of multipotent embryonic mammary gland progenitors.
Nature cell biology
Wuidart A,Sifrim A,Fioramonti M,Matsumura S,Brisebarre A,Brown D,Centonze A,Dannau A,Dubois C,Van Keymeulen A,Voet T,Blanpain C
12-0495 was used in Flow cytometry/Cell sorting to study the timing and mechanisms mediating early lineage segregation of multipotent progenitors during mammary gland development.
Fri Jun 01 00:00:00 EDT 2018
Integrin-Rac signalling for mammary epithelial stem cell self-renewal.
Breast cancer research : BCR
Olabi S,Ucar A,Brennan K,Streuli CH
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Oct 22 00:00:00 EDT 2018
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.
Breast cancer research : BCR
Kim H,Lin Q,Glazer PM,Yun Z
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Mar 06 00:00:00 EST 2018
Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity.
Nature communications
Nguyen QH,Pervolarakis N,Blake K,Ma D,Davis RT,James N,Phung AT,Willey E,Kumar R,Jabart E,Driver I,Rock J,Goga A,Khan SA,Lawson DA,Werb Z,Kessenbrock K
12-0495 was used in Flow cytometry/Cell sorting to profile the transcriptomes of 25,790 primary human breast epithelial cells isolated from reduction mammoplasties, using single cell RNA sequencing.
Wed May 23 00:00:00 EDT 2018
Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer.
Cell reports
Barros-Silva JD,Linn DE,Steiner I,Guo G,Ali A,Pakula H,Ashton G,Peset I,Brown M,Clarke NW,Bronson RT,Yuan GC,Orkin SH,Li Z,Baena E
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Dec 18 00:00:00 EST 2018
Inflammatory memory sensitizes skin epithelial stem cells to tissue damage.
Nature
Naik S,Larsen SB,Gomez NC,Alaverdyan K,Sendoel A,Yuan S,Polak L,Kulukian A,Chai S,Fuchs E
12-0495 was used in Flow cytometry/Cell sorting to study the prolonged memory to acute inflammation that enables mouse epithelial stem cells to hasten barrier restoration after subsequent tissue damage.
Thu Oct 26 00:00:00 EDT 2017
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Cell host & microbe
Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.
Development (Cambridge, England)
Wu HJ,Oh JW,Spandau DF,Tholpady S,Diaz J,Schroeder LJ,Offutt CD,Glick AB,Plikus MV,Koyama S,Foley J
12-0495 was used in Flow cytometry/Cell sorting to show that specialized nipple epidermis is maintained by estrogen-induced repression of TGFβ signalling in the local fibroblasts.
Sat Apr 15 00:00:00 EDT 2017
Low Testosterone Alters the Activity of Mouse Prostate Stem Cells.
The Prostate
Zhou Y,Copeland B,Otto-Duessel M,He M,Markel S,Synold TW,Jones JO
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
Nature communications
Tao L,Xiang D,Xie Y,Bronson RT,Li Z
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Defining stem cell dynamics and migration during wound healing in mouse skin epidermis.
Nature communications
Aragona M,Dekoninck S,Rulands S,Lenglez S,Mascré G,Simons BD,Blanpain C
Wed Mar 01 00:00:00 EST 2017
Stem cell function and stress response are controlled by protein synthesis.
Nature
Blanco S,Bandiera R,Popis M,Hussain S,Lombard P,Aleksic J,Sajini A,Tanna H,Cortés-Garrido R,Gkatza N,Dietmann S,Frye M
12-0495 was used in Flow cytometry/Cell sorting to study how stem cells can revoke translation inhibition pathways to control their function and stress response..
Thu Jun 16 00:00:00 EDT 2016
Characterization of the CD49f+/CD44+/CD24- single-cell derived stem cell population in basal-like DCIS cells.
Oncotarget
Duru N,Gernapudi R,Lo PK,Yao Y,Wolfson B,Zhang Y,Zhou Q
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2016
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Oncotarget
Rane JK,Erb HH,Nappo G,Mann VM,Simms MS,Collins AT,Visakorpi T,Maitland NJ
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Nature communications
Yosef R,Pilpel N,Tokarsky-Amiel R,Biran A,Ovadya Y,Cohen S,Vadai E,Dassa L,Shahar E,Condiotti R,Ben-Porath I,Krizhanovsky V
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Wed Apr 06 00:00:00 EDT 2016
Yap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signaling.
Oncotarget
Sun JG,Chen XW,Zhang LP,Wang J,Diehn M
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration.
Oncotarget
Greenwood E,Maisel S,Ebertz D,Russ A,Pandey R,Schroeder J
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Sep 20 00:00:00 EDT 2016
Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration.
Oncotarget
Greenwood E,Maisel S,Ebertz D,Russ A,Pandey R,Schroeder J
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Sep 20 00:00:00 EDT 2016
Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion.
Skeletal muscle
Penton CM,Badarinarayana V,Prisco J,Powers E,Pincus M,Allen RE,August PR
12-0495 was used in Flow cytometry/Cell sorting to demonstrate laminin 521 is a superior substrate for both short-term and long-term myogenic cell culture applications compared to other commonly utilized substrates.
Tue Dec 13 00:00:00 EST 2016
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
12-0495 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Characterization of autoimmune inflammation induced prostate stem cell expansion.
The Prostate
Wang HH,Wang L,Jerde TJ,Chan BD,Savran CA,Burcham GN,Crist S,Ratliff TL
Thu Oct 01 00:00:00 EDT 2015
The rod domain is not essential for the function of plectin in maintaining tissue integrity.
Molecular biology of the cell
Ketema M,Secades P,Kreft M,Nahidiazar L,Janssen H,Jalink K,de Pereda JM,Sonnenberg A
12-0495 was used in Immunofluorescence to demonstrate that rodless plectin can functionally compensate for the loss of full-length plectin in a knock-in mouse model.
Wed Jul 01 00:00:00 EDT 2015
The Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion.
The Journal of biological chemistry
Shahi P,Slorach EM,Wang CY,Chou J,Lu A,Ruderisch A,Werb Z
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Fri Feb 06 00:00:00 EST 2015
Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation.
PloS one
Zoch A,Mayerl S,Schulz A,Greither T,Frappart L,Rübsam J,Heuer H,Giovannini M,Morrison H
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon May 23 00:00:00 EDT 2016
Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate.
Nature cell biology
Lim A,Shin K,Zhao C,Kawano S,Beachy PA
12-0495 was used in Flow cytometry/Cell sorting to study how spatially restricting Hedgehog signalling can regulate HGF-induced branching of the adult prostate.
Mon Dec 01 00:00:00 EST 2014
In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.
Nature cell biology
Lien WH,Polak L,Lin M,Lay K,Zheng D,Fuchs E
12-0495 was used in Flow cytometry/Cell sorting to show that during hair follicle stem cell quiescence, TCF3, TCF4 and TLE bind coordinately and repress Wnt target genes.
Sat Feb 01 00:00:00 EST 2014
NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells.
Cancer research
Kottakis F,Foltopoulou P,Sanidas I,Keller P,Wronski A,Dake BT,Ezell SA,Shen Z,Naber SP,Hinds PW,McNiel E,Kuperwasser C,Tsichlis PN
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Tue Jul 15 00:00:00 EDT 2014
Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.
Cancer research
Feigin ME,Akshinthala SD,Araki K,Rosenberg AZ,Muthuswamy LB,Martin B,Lehmann BD,Berman HK,Pietenpol JA,Cardiff RD,Muthuswamy SK
12-0495 was used in Flow cytometry/Cell sorting to report that SCRIB mRNA is overexpressed and that SCRIB protein is found away from cell-cell junctions in human breast cancers.
Sun Jun 01 00:00:00 EDT 2014
FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis.
Development (Cambridge, England)
Zhang X,Martinez D,Koledova Z,Qiao G,Streuli CH,Lu P
12-0495 was used in Flow cytometry/Cell sorting to highlight a pleiotropic role for Fgfr2 in stem cell differentiation and branch initiation.
Mon Sep 01 00:00:00 EDT 2014
Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors.
The American journal of pathology
Sackmann-Sala L,Chiche A,Mosquera-Garrote N,Boutillon F,Cordier C,Pourmir I,Pascual-Mathey L,Kessal K,Pigat N,Camparo P,Goffin V
12-0495 was used in Flow cytometry/Cell sorting to provide a deeper understanding of the initial stages of prostate tumorigenesis induced by prolactin.
Sat Nov 01 00:00:00 EDT 2014
Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis.
The American journal of pathology
Burcham GN,Cresswell GM,Snyder PW,Chen L,Liu X,Crist SA,Henry MD,Ratliff TL
12-0495 was used in Flow cytometry/Cell sorting to study the link between prostatitis and prostate cancer development using an inducible mouse model of prostatitis.
Mon Dec 01 00:00:00 EST 2014
DNA methylation of E-cadherin is a priming mechanism for prostate development.
Developmental biology
Keil KP,Abler LL,Mehta V,Altmann HM,Laporta J,Plisch EH,Suresh M,Hernandez LL,Vezina CM
12-0495 was used in Flow cytometry/Cell sorting to investigate the parallels between the signalling during prostate cancer development and prostate organogenesis.
Sat Mar 15 00:00:00 EDT 2014
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Fri Feb 01 00:00:00 EST 2013
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast cancer research : BCR
Kaanta AS,Virtanen C,Selfors LM,Brugge JS,Neel BG
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Dec 08 00:00:00 EST 2014
Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues.
Molecular cancer research : MCR
Smith DA,Kiba A,Zong Y,Witte ON
12-0495 was used in Flow cytometry/Cell sorting to indicate that pro-inflammatory cytokines can activate pathways associated with prostate cancer progression, and synergize with cell-autonomous oncogenic events to promote malignancy.
Tue Oct 01 00:00:00 EDT 2013
Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.
Endocrine-related cancer
Zheng Q,Banaszak L,Fracci S,Basali D,Dunlap SM,Hursting SD,Rich JN,Hjlemeland AB,Vasanji A,Berger NA,Lathia JD,Reizes O
12-0495 was used in Flow cytometry/Cell sorting to explore the role of the leptin receptor in the maintenance of cancer stem cells.
Sun Dec 01 00:00:00 EST 2013
Generation of a novel germline stem cell line expressing a germline-specific reporter in the mouse.
Genesis (New York, N.Y. : 2000)
Shiura H,Ikeda R,Lee J,Sato T,Ogonuki N,Hirose M,Ogura A,Ogawa T,Abe K
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2013
Distinct effects of EGFR ligands on human mammary epithelial cell differentiation.
PloS one
Mukhopadhyay C,Zhao X,Maroni D,Band V,Naramura M
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Fri Jul 11 00:00:00 EDT 2014
Highly upregulated Lhx2 in the Foxn1-/- nude mouse phenotype reflects a dysregulated and expanded epidermal stem cell niche.
PloS one
Bohr S,Patel SJ,Vasko R,Shen K,Huang G,Yarmush ML,Berthiaume F
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Mon Dec 23 00:00:00 EST 2013
Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis.
PloS one
Turaç G,Hindley CJ,Thomas R,Davis JA,Deleidi M,Gasser T,Karaöz E,Pruszak J
12-0495 was used in Flow cytometry/Cell sorting to develop a validated protocol enabling the co-detection and co-expression of surface molecules on neural cell populations.
Tue Feb 04 00:00:00 EST 2014
Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.
Cancer cell
Buchstaller J,McKeever PE,Morrison SJ
12-0495 was used in Flow cytometry/Cell sorting to determine the frequency of malignant peripheral nerve sheath tumour (MPNST) cells with tumourigenic potential in mouse models of MPNST.
Tue Feb 14 00:00:00 EST 2012
Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation.
Stem cells (Dayton, Ohio)
Paik DY,Janzen DM,Schafenacker AM,Velasco VS,Shung MS,Cheng D,Huang J,Witte ON,Memarzadeh S
Published figure using CD49f (Integrin alpha 6) monoclonal antibody (Product # 12-0495-82) in Flow Cytometry
Thu Nov 01 00:00:00 EDT 2012
The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development.
Molecular biology of the cell
Larive RM,Abad A,Cardaba CM,Hernández T,Cañamero M,de Álava E,Santos E,Alarcón B,Bustelo XR
12-0495 was used in Flow cytometry/Cell sorting to investigate the function of the GTPase, R-Ras2/TC21, in vivo.
Fri Jun 01 00:00:00 EDT 2012
Purification and direct transformation of epithelial progenitor cells from primary human prostate.
Nature protocols
Goldstein AS,Drake JM,Burnes DL,Finley DS,Zhang H,Reiter RE,Huang J,Witte ON
12-0495 was used in Flow cytometry/Cell sorting to describe a system to directly transform freshly isolated primary human prostate epithelial cells without previous culture or immortalisation.
Sun May 01 00:00:00 EDT 2011
Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice.
The Journal of clinical investigation
Lyubimova A,Garber JJ,Upadhyay G,Sharov A,Anastasoaie F,Yajnik V,Cotsarelis G,Dotto GP,Botchkarev V,Snapper SB
12-0495 was used in Flow cytometry/Cell sorting to propose that N-WASP acts as a positive regulator of beta-catenin-dependent transcription, modulating differentiation of hair follicle progenitor cells.
Mon Feb 01 00:00:00 EST 2010
Isolation, cultivation and characterization of adult murine prostate stem cells.
Nature protocols
Lukacs RU,Goldstein AS,Lawson DA,Cheng D,Witte ON
12-0495 was used in Flow cytometry/Cell sorting to develop a protocol to isolate, cultivate and characterise adult murine prostate stem cells, allowing further studies in organ replenishment and their role in cancer initiation.
Thu Apr 01 00:00:00 EDT 2010
-Flow-20170216130641.jpg?time=20240507 "CD49f (Integrin alpha 6) Antibody in Flow Cytometry (Flow)")
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-Flow-20170216130641.jpg?time=20240507?time=20240507 "CD49f (Integrin alpha 6) Antibody (12-0495-82) in Flow")
