Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection.
Nature communications
Xu L,Wei C,Chen Y,Wu Y,Shou X,Chen W,Lu D,Sun H,Li W,Yu B,Wang X,Zhang X,Yu Y,Lei Z,Tang R,Zhu J,Li Y,Lu L,Zhou H,Zhou S,Su C,Chen X
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Sat Nov 12 00:00:00 EST 2022
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss.
The Journal of clinical investigation
Yu W,Zhong L,Yao L,Wei Y,Gui T,Li Z,Kim H,Holdreith N,Jiang X,Tong W,Dyment N,Liu XS,Yang S,Choi Y,Ahn J,Qin L
13-0051 was used in Flow cytometry/Cell sorting to identify MALPs as a critical player in controlling bone remodeling during normal bone metabolism and pathological bone loss in a RANKL-dependent fashion.
Tue Jan 19 00:00:00 EST 2021
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.
Immunity
Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B
13-0051-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.
Tue Jun 16 00:00:00 EDT 2020
Th2 cells promote eosinophil-independent pathology in a murine model of allergic bronchopulmonary aspergillosis.
European journal of immunology
Dietschmann A,Schruefer S,Krappmann S,Voehringer D
13-0051-82 was used in Flow Cytometry to use a mouse model of ABPA to investigate the role of eosinophils and T cell-derived IL-4/IL-13 for induction of allergic lung inflammation.
Wed Jul 01 00:00:00 EDT 2020
The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae.
Frontiers in immunology
Ercoli G,Ramos-Sevillano E,Nakajima R,de Assis RR,Jasinskas A,Goldblatt D,Felgner P,Weckbecker G,Brown J
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
13-0051 was used in Flow cytometry/Cell sorting to show that the erythroid transcription factor GATA-1 - that typically binds T/AGATA sites - can also recognise CGATA elements, but only if the CpG dinucleotide is unmethylated.
Fri May 22 00:00:00 EDT 2020
Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover.
eLife
Xu AQ,Barbosa RR,Calado DP
13-0051 was used in Flow cytometry/Cell sorting to characterize a genetic tool (JchaincreERT2) in the mouse that permits first-ever specific genetic manipulation in PCs in vivo, across immunoglobulin isotypes.
Mon Nov 02 00:00:00 EST 2020
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.
eLife
Zhong L,Yao L,Tower RJ,Wei Y,Miao Z,Park J,Shrestha R,Wang L,Yu W,Holdreith N,Huang X,Zhang Y,Tong W,Gong Y,Ahn J,Susztak K,Dyment N,Li M,Long F,Chen C,Seale P,Qin L
13-0051 was used in Flow cytometry/Cell sorting to computationally define mesenchymal progenitors at different stages and delineate their bi-lineage differentiation paths in young, adult and aging mice.
Tue Apr 14 00:00:00 EDT 2020
Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence.
Journal of visualized experiments : JoVE
Kesarwani M,Kincaid Z,Azam M
13-0051 was used in Flow cytometry/Cell sorting to provide methods for target validation using in vitro and in vivo mouse models.
Mon Jan 07 00:00:00 EST 2019
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
13-0051 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.
Journal of virology
Niemeyer BF,Oko LM,Medina EM,Oldenburg DG,White DW,Cool CD,Clambey ET,van Dyk LF
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Thu Mar 15 00:00:00 EDT 2018
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.
Experimental hematology
Serrano-Lopez J,Nattamai K,Pease NA,Shephard MS,Wellendorf AM,Sertorio M,Smith EA,Geiger H,Wells SI,Cancelas JA,Privette Vinnedge LM
13-0051 was used in Flow cytometry/Cell sorting to investigate the role of DEK in normal hematopoiesis and response to DNA damaging agents in vivo.
Thu Mar 01 00:00:00 EST 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.
Genome biology
Grigoryan A,Guidi N,Senger K,Liehr T,Soller K,Marka G,Vollmer A,Markaki Y,Leonhardt H,Buske C,Lipka DB,Plass C,Zheng Y,Mulaw MA,Geiger H,Florian MC
13-0051 was used in Flow cytometry/Cell sorting to show that not all histone modifications display a polar localization and that a reduction in H4K16ac amount and loss of epipolarity are specific to aged HSCs.
Wed Nov 07 00:00:00 EST 2018
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression.
Molecular cell
Ren G,Jin W,Cui K,Rodrigez J,Hu G,Zhang Z,Larson DR,Zhao K
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Thu Sep 21 00:00:00 EDT 2017
Naïve helper T cells with high CD5 expression have increased calcium signaling.
PloS one
Freitas CMT,Hamblin GJ,Raymond CM,Weber KS
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Tue Sep 26 00:00:00 EDT 2017
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Wed May 25 00:00:00 EDT 2016
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-0051 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 EDT 2015
The prostaglandin D₂ receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung.
Mucosal immunology
Wojno ED,Monticelli LA,Tran SV,Alenghat T,Osborne LC,Thome JJ,Willis C,Budelsky A,Farber DL,Artis D
13-0051 was used in Flow cytometry/Cell sorting to demonstrate that expression of the prostaglandin D2 receptor CRTH2 regulates the accumulation of ILC2s in the lung.
Sun Nov 01 00:00:00 EDT 2015
Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice.
Free radical biology & medicine
Xu G,Wu H,Zhang J,Li D,Wang Y,Wang Y,Zhang H,Lu L,Li C,Huang S,Xing Y,Zhou D,Meng A
13-0051 was used in Flow cytometry/Cell sorting to study how metformin has the potential to be used as a novel radioprotectant to ameliorate TBI-induced long-term BM injury.
Thu Oct 01 00:00:00 EDT 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD5 monoclonal antibody (Product # 13-0051-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals.
The Journal of experimental medicine
Heizmann B,Kastner P,Chan S
13-0051 was used in Flow cytometry/Cell sorting to investigate the transcriptional programs that drive pre-B cell differentiation, showing that Ikaros is absolutely required by attenuating IL-7 signals.
Mon Dec 16 00:00:00 EST 2013
Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
The Journal of experimental medicine
Kaji T,Ishige A,Hikida M,Taka J,Hijikata A,Kubo M,Nagashima T,Takahashi Y,Kurosaki T,Okada M,Ohara O,Rajewsky K,Takemori T
13-0051 was used in Flow cytometry/Cell sorting to reveal distinct cellular pathways that select germline-encoded and somatically mutated antibodies into immunological memory.
Mon Oct 22 00:00:00 EDT 2012
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.
Stem cells (Dayton, Ohio)
Khandanpour C,Kosan C,Gaudreau MC,Dührsen U,Hébert J,Zeng H,Möröy T
13-0051 was used in Flow cytometry/Cell sorting to demonstrate that growth factor independence 1 protects against apoptosis in haematopoietic stem cells and prevents the development of myeloproliferative diseases.
Tue Feb 01 00:00:00 EST 2011
The actin-bundling protein L-plastin is essential for marginal zone B cell development.
Journal of immunology (Baltimore, Md. : 1950)
Todd EM,Deady LE,Morley SC
13-0051 was used in Flow cytometry/Cell sorting to study the role of the actin-bundling protein L-plastin in B cell chemotaxis.
Thu Sep 15 00:00:00 EDT 2011
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.
The Journal of experimental medicine
Fisson S,Darrasse-Jèze G,Litvinova E,Septier F,Klatzmann D,Liblau R,Salomon BL
13-0051 was used in Flow cytometry/Cell sorting to investigate fundamental characteristics of CD4+ CD25+ Tregs, showing continuous activation of autoreactive Tregs at steady state.
Mon Sep 01 00:00:00 EDT 2003