Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection.
Nature communications
Xu L,Wei C,Chen Y,Wu Y,Shou X,Chen W,Lu D,Sun H,Li W,Yu B,Wang X,Zhang X,Yu Y,Lei Z,Tang R,Zhu J,Li Y,Lu L,Zhou H,Zhou S,Su C,Chen X
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Sat Nov 12 00:00:00 EST 2022
Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages.
Cell reports
West HC,Davies J,Henderson S,Adegun OK,Ward S,Ferrer IR,Tye CA,Vallejo AF,Jardine L,Collin M,Polak ME,Bennett CL
17-0051-82 was used in Flow cytometry/Cell sorting to demonstrate that pathology initiates dermis-specific macrophage differentiation and show that aGVHD-primed macrophages continue to dominate the dermal compartment at the relative expense of quiescent MHCIIint cells.
Tue May 17 00:00:00 EDT 2022
The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.
PLoS pathogens
Niemeyer BF,Sanford B,Gibson JE,Berger JN,Oko LM,Medina E,Clambey ET,van Dyk LF
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
Sadik A,Somarribas Patterson LF,Öztürk S,Mohapatra SR,Panitz V,Secker PF,Pfänder P,Loth S,Salem H,Prentzell MT,Berdel B,Iskar M,Faessler E,Reuter F,Kirst I,Kalter V,Foerster KI,Jäger E,Guevara CR,Sobeh M,Hielscher T,Poschet G,Reinhardt A,Hassel JC,Zapatka M,Hahn U,von Deimling A,Hopf C,Schlichting R,Escher BI,Burhenne J,Haefeli WE,Ishaque N,Böhme A,Schäuble S,Thedieck K,Trump S,Seiffert M,Opitz CA
17-0051 was used in Flow cytometry/Cell sorting to show that IL4I1 blockade opens new avenues for cancer therapy.
Thu Sep 03 00:00:00 EDT 2020
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
Cell host & microbe
McNamara HA,Idris AH,Sutton HJ,Vistein R,Flynn BJ,Cai Y,Wiehe K,Lyke KE,Chatterjee D,Kc N,Chakravarty S,Lee Sim BK,Hoffman SL,Bonsignori M,Seder RA,Cockburn IA
17-0051 was used in Flow cytometry/Cell sorting to suggest that antibody feedback drives the diversification of immune responses and that vaccination for malaria will require targeting multiple antigens.
Wed Oct 07 00:00:00 EDT 2020
The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae.
Frontiers in immunology
Ercoli G,Ramos-Sevillano E,Nakajima R,de Assis RR,Jasinskas A,Goldblatt D,Felgner P,Weckbecker G,Brown J
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms.
Nature communications
Watanabe M,Lu Y,Breen M,Hodes RJ
17-0051 was used in Flow cytometry/Cell sorting to reveal a function of B7-CD28 co-stimulation in shaping the T cell repertoire and limiting autoimmunity through both thymic clonal deletion and Treg cell generation.
Tue Dec 08 00:00:00 EST 2020
Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB.
Immunity
Webb LV,Barbarulo A,Huysentruyt J,Vanden Berghe T,Takahashi N,Ley S,Vandenabeele P,Seddon B
17-0051-82 was used in Flow Cytometry to show that IKK was required to protect Rel-deficient thymocytes from RIPK1-dependent cell death, underscoring the NF-κB-independent function of IKK during thymic development.
Tue Feb 19 00:00:00 EST 2019
ImmGen report: sexual dimorphism in the immune system transcriptome.
Nature communications
Gal-Oz ST,Maier B,Yoshida H,Seddu K,Elbaz N,Czysz C,Zuk O,Stranger BE,Ner-Gaon H,Shay T
17-0051 was used in Flow cytometry/Cell sorting to show transcriptional sexual dimorphism in macrophages.
Fri Sep 20 00:00:00 EDT 2019
Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.
Journal of virology
Niemeyer BF,Oko LM,Medina EM,Oldenburg DG,White DW,Cool CD,Clambey ET,van Dyk LF
17-0051 was used in Flow cytometry/Cell sorting to characterise the role of host p18INK4c in inhibiting gammaherpesvirus reactivation and pathogenesis.
Thu Mar 15 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Nature medicine
Fenouille N,Bassil CF,Ben-Sahra I,Benajiba L,Alexe G,Ramos A,Pikman Y,Conway AS,Burgess MR,Li Q,Luciano F,Auberger P,Galinsky I,DeAngelo DJ,Stone RM,Zhang Y,Perkins AS,Shannon K,Hemann MT,Puissant A,Stegmaier K
17-0051 was used in Flow cytometry/Cell sorting to investigate the effect of MECOM on cellular metabolism.
Wed Mar 01 00:00:00 EST 2017
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression.
Molecular cell
Ren G,Jin W,Cui K,Rodrigez J,Hu G,Zhang Z,Larson DR,Zhao K
17-0051 was used in Flow cytometry/Cell sorting to study the role of CTCF in regulating cell-to-cell variation of expression.
Thu Sep 21 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
17-0051 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Naïve helper T cells with high CD5 expression have increased calcium signaling.
PloS one
Freitas CMT,Hamblin GJ,Raymond CM,Weber KS
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Tue Sep 26 00:00:00 EDT 2017
NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Nature communications
Märklin M,Heitmann JS,Fuchs AR,Truckenmüller FM,Gutknecht M,Bugl S,Saur SJ,Lazarus J,Kohlhofer U,Quintanilla-Martinez L,Rammensee HG,Salih HR,Kopp HG,Haap M,Kirschniak A,Kanz L,Rao A,Wirths S,Müller MR
17-0051 was used in Flow cytometry/Cell sorting to identify NFAT2 as a crucial regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Mon Oct 02 00:00:00 EDT 2017
Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice.
Arteriosclerosis, thrombosis, and vascular biology
Srikakulapu P,Hu D,Yin C,Mohanta SK,Bontha SV,Peng L,Beer M,Weber C,McNamara CA,Grassia G,Maffia P,Manz RA,Habenicht AJ
17-0051 was used in Flow cytometry/Cell sorting to study how artery tertiary lymphoid organs can orchestrate B-cell responses in the diseased aorta.
Wed Jun 01 00:00:00 EDT 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Wed May 25 00:00:00 EDT 2016
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.
The Journal of experimental medicine
Fiala GJ,Janowska I,Prutek F,Hobeika E,Satapathy A,Sprenger A,Plum T,Seidl M,Dengjel J,Reth M,Cesca F,Brummer T,Minguet S,Schamel WW
17-0051 was used in Flow cytometry/Cell sorting to study Kidins220/ARMS binding to the B cell antigen receptor and its regulation of B cell development and activation.
Mon Sep 21 00:00:00 EDT 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD5 monoclonal antibody (Product # 17-0051-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow.
Journal of immunology (Baltimore, Md. : 1950)
Reynolds AE,Kuraoka M,Kelsoe G
17-0051 was used in Flow cytometry/Cell sorting to investigate the origin of natural IgM, showing that it is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow.
Thu Jan 01 00:00:00 EST 2015
Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells.
Molecular metabolism
Singer K,DelProposto J,Morris DL,Zamarron B,Mergian T,Maley N,Cho KW,Geletka L,Subbaiah P,Muir L,Martinez-Santibanez G,Lumeng CN
17-0051 was used in Flow cytometry/Cell sorting to demonstrate how metabolic signals potentiate leukocyte production and dietary priming of haematopoietic progenitors contributes to adipose tissue inflammation.
Mon Sep 01 00:00:00 EDT 2014
Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice.
International immunology
Honjo K,Kubagawa Y,Suzuki Y,Takagi M,Ohno H,Bucy RP,Izui S,Kubagawa H
17-0051 was used in Flow cytometry/Cell sorting to determine the impact of Fcmr ablation on autoimmunity.
Mon Dec 01 00:00:00 EST 2014
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
The EMBO journal
Kasler HG,Lim HW,Mottet D,Collins AM,Lee IS,Verdin E
17-0051 was used in Flow cytometry/Cell sorting to examine the effect of blocking TCR-dependent nuclear export of HDAC7 during thymic selection, showing that HDAC7 is required for immune self-tolerance.
Wed Nov 28 00:00:00 EST 2012
Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease.
The American journal of pathology
Szczepanek SM,McNamara JT,Secor ER,Natarajan P,Guernsey LA,Miller LA,Ballesteros E,Jellison E,Thrall RS,Andemariam B
17-0051 was used in Flow cytometry/Cell sorting to investigate the relationship between functional asplenia from infarctions and increased infectious mortality in a mouse model of sickle-cell disease.
Thu Nov 01 00:00:00 EDT 2012
Requirement for complement in antibody responses is not explained by the classic pathway activator IgM.
Proceedings of the National Academy of Sciences of the United States of America
Rutemark C,Alicot E,Bergman A,Ma M,Getahun A,Ellmerich S,Carroll MC,Heyman B
17-0051 was used in Flow cytometry/Cell sorting to investigate the role of the classical pathway activator IgM in complement activated antibody responses.
Tue Oct 25 00:00:00 EDT 2011
ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.
The Journal of experimental medicine
Gibb DR,El Shikh M,Kang DJ,Rowe WJ,El Sayed R,Cichy J,Yagita H,Tew JG,Dempsey PJ,Crawford HC,Conrad DH
17-0051 was used in Flow cytometry/Cell sorting to investigate the role of ADAM10 cleavage events in immune cell development.
Mon Mar 15 00:00:00 EDT 2010
