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Product Details
PA5-116539
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 16-288 of human CD64 (NP_0005571)
Conjugate
Form
Liquid
Concentration
2.34 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901170
Product Specific Information
Immunogen sequence: QVDTTKAVIT LQPPWVSVFQ EETVTLHCEV LHLPGSSSTQ WFLNGTATQT STPSYRITSA SVNDSGEYRC QRGLSGRSDP IQLEIHRGWL LLQVSSRVFT EGEPLALRCH AWKDKLVYNV LYYRNGKAFK FFHWNSNLTI LKTNISHNGT YHCSGMGKHR YTSAGISVTV KELFPAPVLN ASVTSPLLEG NLVTLSCETK LLLQRPGLQL YFSFYMGSKT LRGRNTSSEY QILTARREDS GLYWCEAATE DGNVLKRSPE LELQVLGLQL PTP
Positive Samples: LO2, U-937, Mouse liver, Rat liver
Target Information
CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD64; CD64 antigen; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRIa; FcgRI; FcRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; High affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; IgG high affinity Fc receptor; RP11-196G18.2
Gene Aliases: AI323638; AV092959; CD64; CD64A; FCG1; FcgammaRI; FCGR1; FCGR1A; Fcgr1b; FCRI; IGFR1; IGGHAFC
UniProt ID: (Human) P12314, (Mouse) P26151
Entrez Gene ID: (Human) 2209, (Mouse) 14129, (Rat) 295279
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
receptor-mediated endocytosis
phagocytosis, engulfment
immune response
signal transduction
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of immune response
interferon-gamma-mediated signaling pathway
antibody-dependent cellular cytotoxicity
positive regulation of type IIa hypersensitivity
positive regulation of type III hypersensitivity
immune system process
phagocytosis, recognition
cell surface receptor signaling pathway
response to bacterium
antigen processing and presentation of exogenous antigen
Fc-gamma receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
innate immune response
positive regulation of phagocytosis
positive regulation of phagocytosis, engulfment
response to estradiol
response to epinephrine
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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