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CD70 Antibody (MA5-44537) in WB
Western Blot of CD70 in whole cell lysate (50 µg) from 786-O, HEK293T, HeLa, and Hs 294T cells. Samples were incubated with CD70 monoclonal antibody (Product # MA5-44538) at a dilution of 1:1000, followed by HRP-conjugated goat anti-rabbit IgG (exposure time of 30 seconds) Lower Panel: Rabbit anti-Actin .
Product Details
MA5-44537
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
BLR176J
Immunogen
Recombinant protein representing the extracellular domain of Human CD70 (residues 50-193).
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
purified
Storage buffer
BBS, pH 7.8-8.6, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
2-8°C
Shipping conditions
Wet ice
RRID
AB_2926667
Target Information
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD27 ligand; CD27-L; CD70; CD70 antigen; Ki-24 antigen; surface antigen CD70; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; Tumor necrosis factor ligand superfamily member 7
Gene Aliases: CD27L; CD27LG; CD70; TNFSF7; TNLG8A
UniProt ID: (Human) P32970
Entrez Gene ID: (Human) 970
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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