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Invitrogen
CD79b Monoclonal Antibody (CB3-1), PE, eBioscience™
Product Details
12-0793-42
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Recommended Isotype Control
Class
Monoclonal
Type
Antibody
Clone
CB3-1
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
5 µL/Test
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1834459
Product Specific Information
Description: This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain. Together with the Ig alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM). CD79b expression is exclusive to B lymphocytes and B cell lymphomas. Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.
Applications Reported: This CB3-1 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This CB3-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha /I g beta heterodimer tranduces signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
Bioinformatics
Protein Aliases: B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; Ig beta; Ig-beta; Immunoglobulin-associated B29 protein; RP23-418O11.7
Gene Aliases: AGM6; B29; CD79B; IGB
UniProt ID: (Human) P40259
Entrez Gene ID: (Human) 974
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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