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CD79b Antibody (14-0793-82) in Flow
Staining of normal human peripheral blood cells with Anti-Human CD19 APC (Product # 17-0199-42) and 0.25 µg of Mouse IgG1 kappa Isotype Control Purified (Product # 14-4714-82) (left) or 0.25 µg of Anti-Human CD79b Purified (right) followed by F (ab')2 Anti-Mouse IgG PE (Product # 12-4012). Cells in the lymphocyte gate were used for analysis.
Product Details
14-0793-82
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CB3-1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10545905
Product Specific Information
Description: This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain. Together with the Ig-alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM). CD79b expression is exclusive to B lymphocytes and B cell lymphomas. Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.
Applications Reported: This CB3-1 antibody has been reported for use in flow cytometric analysis and immunoblotting (WB).
Applications Tested: This CB3-1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Purity: Greater than 90%, as determined by SDS-PAGE.
Aggregation: Less than 10%, as determined by HPLC.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha /I g beta heterodimer tranduces signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; Ig beta; Ig-beta; Immunoglobulin-associated B29 protein; RP23-418O11.7
Gene Aliases: AGM6; B29; CD79B; IGB
UniProt ID: (Human) P40259
Entrez Gene ID: (Human) 974
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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