Product References
hMSCs treatment attenuates murine herpesvirus-68 (MHV-68) pneumonia through altering innate immune response via ROS/NLRP3 signaling pathway.
Molecular biomedicine
Qin A,Wang XJ,Fu J,Shen A,Huang X,Chen Z,Wu H,Jiang Y,Wang Q,Chen F,Xiang AP,Yu X
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Sep 14 00:00:00 EDT 2023
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Bioactive materials
Li S,Zhang L,Liu C,Kim J,Su K,Chen T,Zhao L,Lu X,Zhang H,Cui Y,Cui X,Yuan F,Pan H
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
Hydrochlorothiazide-induced glucose metabolism disorder is mediated by the gut microbiota via LPS-TLR4-related macrophage polarization.
iScience
Luo JQ,Ren H,Chen MY,Zhao Q,Yang N,Liu Q,Gao YC,Zhou HH,Huang WH,Zhang W
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Fri Jul 21 00:00:00 EDT 2023
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
CD8α+ dendritic cells potentiate antitumor and immune activities against murine ovarian cancers.
Scientific reports
Lee SW,Lee H,Lee KW,Kim MJ,Kang SW,Lee YJ,Kim H,Kim YM
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Immunity, inflammation and disease
Tan H,Cao L
12-0801-82 was used in Flow cytometry/Cell sorting to study the role and molecular mechanisms of OmpA-induced mouse bone marrow-derived dendritic cells (BMDCs) autophagy in the immune response of A. baumannii.
Sat Apr 01 00:00:00 EDT 2023
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Immunity, inflammation and disease
Tan H,Cao L
12-0801-82 was used in Flow cytometry/Cell sorting to study the role and molecular mechanisms of OmpA-induced mouse bone marrow-derived dendritic cells (BMDCs) autophagy in the immune response of A. baumannii.
Sat Apr 01 00:00:00 EDT 2023
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Plasmodium infection disrupts the T follicular helper cell response to heterologous immunization.
eLife
Fontana MF,Ollmann Saphire E,Pepper M
12-0801-82 was used in Flow cytometry/Cell sorting to provide mechanistic insight into the development of both Plasmodium-specific and heterologous adaptive responses in hosts with malaria.
Mon Jan 30 00:00:00 EST 2023
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.
Materials today. Bio
Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Combining gut microbiota modulation and chemotherapy by capecitabine-loaded prebiotic nanoparticle improves colorectal cancer therapy.
Nature communications
Lang T,Zhu R,Zhu X,Yan W,Li Y,Zhai Y,Wu T,Huang X,Yin Q,Li Y
12-0801-82 was used in In vitro Assay to create a prebiotic-based nanoparticle carrier for capecitabine, enhancing its anti-tumor efficacy in a colorectal cancer mouse model by modulating gut microbiota and increasing drug concentrations within tumors.
Mon Aug 07 00:00:00 EDT 2023
TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Zhao J,Jia L,Tao Y,Zhao X,Yang J,Lu Y,Yan Y,Mao L,Hu L,Lu J,Guo M,Chen C,Zhou Y,Wen Z,He Z,Xu L
12-0801-82 was used in Flow cytometry/Cell sorting to suggest that the clone selection in thymus in Endotoxin tolerance may confer protection against microbial sepsis.
Wed Mar 01 00:00:00 EST 2023
Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment.
Acta pharmaceutica Sinica. B
Xi L,Lin Z,Qiu F,Chen S,Li P,Chen X,Wang Z,Zheng Y
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Nanoplatform Self-Assembly from Small Molecules of Porphyrin Derivatives for NIR-II Fluorescence Imaging Guided Photothermal-Immunotherapy.
Advanced healthcare materials
Cao Y,Wei D,Yang L,Luo Z,Yu P,Li H,Zhang C,Liu X,Wu F,Wu M,Zeng Y
12-0801-82 was used in Flow Cytometry to provide a promising therapeutic paradigm with porphyrin derivatives nano-assembly as phototheranostic agents for the treatment of aggressive tumors with high efficiency.
Wed Jun 01 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses.
Nature communications
Guo Y,Wang SZ,Zhang X,Jia HR,Zhu YX,Zhang X,Gao G,Jiang YW,Li C,Chen X,Wu SY,Liu Y,Wu FG
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
TcpC Inhibits M1 but Promotes M2 Macrophage Polarization via Regulation of the MAPK/NF-κB and Akt/STAT6 Pathways in Urinary Tract Infection.
Cells
Fang J,Ou Q,Wu B,Li S,Wu M,Qiu J,Cen N,Hu K,Che Y,Ma Y,Pan J
12-0801-82 was used in Flow cytometry/Cell sorting to illuminate the regulatory effects of TcpC on macrophage M1/M2 polarization.
Sun Aug 28 00:00:00 EDT 2022
TcpC Inhibits M1 but Promotes M2 Macrophage Polarization via Regulation of the MAPK/NF-κB and Akt/STAT6 Pathways in Urinary Tract Infection.
Cells
Fang J,Ou Q,Wu B,Li S,Wu M,Qiu J,Cen N,Hu K,Che Y,Ma Y,Pan J
12-0801-82 was used in Flow cytometry/Cell sorting to illuminate the regulatory effects of TcpC on macrophage M1/M2 polarization.
Sun Aug 28 00:00:00 EDT 2022
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
Theranostics
Mao Q,Min J,Zeng R,Liu H,Li H,Zhang C,Zheng A,Lin J,Liu X,Wu M
12-0801-82 was used in Flow cytometry/Cell sorting to provides a promising self-assembled traditional Chinese nanomedicine to improve immunotherapy for colorectal cancer (CRC), which might be applicable for future clinical translation.
Thu Sep 29 00:00:00 EDT 2022
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
Theranostics
Mao Q,Min J,Zeng R,Liu H,Li H,Zhang C,Zheng A,Lin J,Liu X,Wu M
12-0801-82 was used in Flow cytometry/Cell sorting to provides a promising self-assembled traditional Chinese nanomedicine to improve immunotherapy for colorectal cancer (CRC), which might be applicable for future clinical translation.
Thu Sep 29 00:00:00 EDT 2022
Cytosolic Nuclear Sensor Dhx9 Controls Medullary Thymic Epithelial Cell Differentiation by p53-Mediated Pathways.
Frontiers in immunology
Dong X,Zhang J,Zhang Q,Liang Z,Xu Y,Zhao Y,Zhang B
12-0801-82 was used in Flow cytometry/Cell sorting to reveal that Dhx9, a cytosolic nuclear sensor recognizes viral DNA or RNA, playing an important role in mTEC development and function in mice.
Tue Jun 21 00:00:00 EDT 2022
A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.
Biomaterials
Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
12-0801 was used in Flow cytometry/Cell sorting to elucidate the potential regulatory mechanism of PGE2 on the migration of dendritic cells.
Fri Jan 01 00:00:00 EST 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
12-0801 was used in Flow cytometry/Cell sorting to elucidate the potential regulatory mechanism of PGE2 on the migration of dendritic cells.
Fri Jan 01 00:00:00 EST 2021
Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat-treated tumor cell lysates enhance antitumor activity in murine lung cancer.
Oncology letters
Chen H,Tan J,Li X,Li H,Wu W,Wu Y,Zhang J,Gu L
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy.
Journal of hematology & oncology
Kim HR,Park JS,Park JH,Yasmin F,Kim CH,Oh SK,Chung IJ,Jun CD
12-0801 was used in Flow cytometry/Cell sorting to indicate that cell-permeable transgelin-2 have a potential clinical value as a cancer immunotherapy based on DCs.
Wed Mar 17 00:00:00 EDT 2021
Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy.
Journal of hematology & oncology
Kim HR,Park JS,Park JH,Yasmin F,Kim CH,Oh SK,Chung IJ,Jun CD
12-0801 was used in Flow cytometry/Cell sorting to indicate that cell-permeable transgelin-2 have a potential clinical value as a cancer immunotherapy based on DCs.
Wed Mar 17 00:00:00 EDT 2021
Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Cells
Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Nov 15 00:00:00 EST 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Azithromycin alleviates systemic lupus erythematosus via the promotion of M2 polarisation in lupus mice.
Cell death discovery
Wang J,Chen Q,Zhang Z,Wang S,Wang Y,Xiang M,Liang J,Xu J
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Fri Apr 16 00:00:00 EDT 2021
Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics.
iScience
Nascimento Da Conceicao V,Sun Y,Ramachandran K,Chauhan A,Raveendran A,Venkatesan M,DeKumar B,Maity S,Vishnu N,Kotsakis GA,Worley PF,Gill DL,Mishra BB,Madesh M,Singh BB
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
Urolithin A ameliorates experimental autoimmune encephalomyelitis by targeting aryl hydrocarbon receptor.
EBioMedicine
Shen PX,Li X,Deng SY,Zhao L,Zhang YY,Deng X,Han B,Yu J,Li Y,Wang ZZ,Zhang Y
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
12-0801-82 was used in Flow Cytometry to provide an instructive basis for the roles of Smek1 in EAE and broaden the understanding of the genetic factors involved in the pathogenesis of autoimmune demyelination.
Mon Jun 28 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity.
Immunity
Turner JA,Stephen-Victor E,Wang S,Rivas MN,Abdel-Gadir A,Harb H,Cui Y,Fanny M,Charbonnier LM,Fong JJH,Benamar M,Wang L,Burton OT,Bansal K,Bry L,Zhu C,Li QZ,Clement RL,Oettgen HC,Crestani E,Rachid R,Sage PT,Chatila TA
12-0801-82 was used in Flow Cytometry to show that Treg cells in food allergy (FA) had decreased expression of transforming growth factor beta 1 (TGF-β1) because of interleukin-4 (IL-4)- and signal transducer and activator of transciription-6 (STAT6)-dependent inhibition of Tgfb1 transcription.
Tue Dec 15 00:00:00 EST 2020
Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells.
Cancer cell
Sagnella SM,Yang L,Stubbs GE,Boslem E,Martino-Echarri E,Smolarczyk K,Pattison SL,Vanegas N,St Clair E,Clarke S,Boockvar J,MacDiarmid JA,Brahmbhatt H
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that tumor-targeting EDV nanocells function as an immunotherapeutic by delivering a cytotoxin in conjunction with activation of the immune system.
Mon Mar 16 00:00:00 EDT 2020
The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses.
The Journal of experimental medicine
Chen L,Christian DA,Kochanowsky JA,Phan AT,Clark JT,Wang S,Berry C,Oh J,Chen X,Roos DS,Beiting DP,Koshy AA,Hunter CA
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway.
OncoTargets and therapy
Liu Y,Yin Z,Lu P,Ma Y,Luo B,Xiang L,Zhang W,He Y,Liang X
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Interleukin-9 Inhibits Lung Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages.
Molecules and cells
Park SM,Do-Thi VA,Lee JO,Lee H,Kim YS
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that IL-9 can induce an anti-metastasis effect by enhancing the polarization and proliferation of M1 macrophages.
Sun May 31 00:00:00 EDT 2020
Interleukin-9 Inhibits Lung Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages.
Molecules and cells
Park SM,Do-Thi VA,Lee JO,Lee H,Kim YS
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that IL-9 can induce an anti-metastasis effect by enhancing the polarization and proliferation of M1 macrophages.
Sun May 31 00:00:00 EDT 2020
Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.
Molecular medicine reports
Li G,Yang L,Li D,Zhang J,Du L,Xia L,Liu Y,Hu W
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Antitumor immunity targeting fibroblast activation protein-α in a mouse Lewis lung carcinoma model.
Oncology letters
Xie J,Yuan S,Peng L,Li H,Niu L,Xu H,Guo X,Yang M,Duan F
12-0801 was used in Flow cytometry/Cell sorting to investigate the use of CAFs-targeted immunotherapy to fibroblast activation protein-α (FAP-α) expressed in CAFs.
Wed Jul 01 00:00:00 EDT 2020
Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity.
Journal for immunotherapy of cancer
Efimova I,Catanzaro E,Van der Meeren L,Turubanova VD,Hammad H,Mishchenko TA,Vedunova MV,Fimognari C,Bachert C,Coppieters F,Lefever S,Skirtach AG,Krysko O,Krysko DV
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Carrot Pomace Polysaccharide (CPP) Improves Influenza Vaccine Efficacy in Immunosuppressed Mice via Dendritic Cell Activation.
Nutrients
Sun P,Kim Y,Lee H,Kim J,Han BK,Go E,Kwon S,Kang JG,You S,Kwon J
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Wed Sep 09 00:00:00 EDT 2020
Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma.
Cancers
Trempolec N,Doix B,Degavre C,Brusa D,Bouzin C,Riant O,Feron O
12-0801-82 was used in Flow Cytometry to indicate that PDT-based DC vaccination is particularly suited to induce a potent immune response against peritoneal mesothelioma.
Thu Feb 27 00:00:00 EST 2020
Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma.
Cancers
Trempolec N,Doix B,Degavre C,Brusa D,Bouzin C,Riant O,Feron O
12-0801-82 was used in Flow Cytometry to indicate that PDT-based DC vaccination is particularly suited to induce a potent immune response against peritoneal mesothelioma.
Thu Feb 27 00:00:00 EST 2020
MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner.
Cell reports
Cordeiro B,Jeon P,Boukhaled GM,Corrado M,Lapohos O,Roy DG,Williams K,Jones RG,Gruenheid S,Sagan SM,Krawczyk CM
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that miR-9 facilitates the transition of DCs from steady state to mature state by regulating the expression of several negative regulators of DC function in a cell-type-specific manner.
Tue May 05 00:00:00 EDT 2020
Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response.
Cancers
Trempolec N,Degavre C,Doix B,Brusa D,Corbet C,Feron O
12-0801-82 was used in Flow cytometry/Cell sorting to identify that acidic mesothelioma milieu drives dendritic cell (DC) dysfunction and altered T cell response through pharmacologically reversible TGF-β2-dependent mechanisms.
Tue May 19 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.
Frontiers in immunology
Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR
12-0801 was used in Flow cytometry/Cell sorting to show dendritic cell PTPN2 might explain the central role for PTPN2 in the immune system to maintain immune tolerance.
Mon Apr 12 00:00:00 EDT 2021
Disruption of Midkine gene reduces traumatic brain injury through the modulation of neuroinflammation.
Journal of neuroinflammation
Takada S,Sakakima H,Matsuyama T,Otsuka S,Nakanishi K,Norimatsu K,Itashiki Y,Tani A,Kikuchi K
12-0801-82 was used in Flow cytometry/Cell sorting to suggest that MK-deficiency reduced tissue infiltration of microglia/macrophages and altered their polarization status thereby reducing neuroinflammation, neuronal apoptosis, and tissue loss and improving neurological outcomes after TBI.
Wed Jan 29 00:00:00 EST 2020
A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis.
The Journal of clinical investigation
Han YH,Shin KO,Kim JY,Khadka DB,Kim HJ,Lee YM,Cho WJ,Cha JY,Lee BJ,Lee MO
12-0801 was used in Flow cytometry/Cell sorting to study the hepatic microenvironments that support the function of RORa as a polarity regulator.
Mon Mar 11 00:00:00 EDT 2019
Multilamellar Vaccine Particle Elicits Potent Immune Activation with Protein Antigens and Protects Mice against Ebola Virus Infection.
ACS nano
Fan Y,Stronsky SM,Xu Y,Steffens JT,van Tongeren SA,Erwin A,Cooper CL,Moon JJ
12-0801 was used in Flow cytometry/Cell sorting to suggest that multilamellar vaccine particles (MVPs) offer a promising platform for improving recombinant protein-based vaccine approaches.
Tue Oct 22 00:00:00 EDT 2019
cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection.
International journal of molecular sciences
Li Q,Liu C,Yue R,El-Ashram S,Wang J,He X,Zhao D,Zhou X,Xu L
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Feb 19 00:00:00 EST 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma.
Journal of immunology research
Zhou Y,Liu F,Li C,Shi G,Xu X,Luo X,Zhang Y,Fu J,Zeng A,Chen L
12-0801 was used in Flow cytometry/Cell sorting to explored the anti-tumour effects of dendritic cell vaccines harbouring aspartate-Β-hydroxylase.
Mon Nov 05 00:00:00 EST 2018
PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine.
Journal of Cancer
Zhang X,Shi X,Li J,Mo L,Hu Z,Gao J,Wu S,Long Z
12-0801 was used in Flow cytometry/Cell sorting to investigate whether PD-L1 mediated adaptive resistance could occur in treatment with Anchored-GM-CSF vaccine and whether PD-1 blockade combined with Anchored-GM-CSF vaccine could induce a greater anti-tumour immune response than either immunotherapy alone.
Thu Oct 01 00:00:00 EDT 2020
T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells.
Nature communications
Kim HR,Mun Y,Lee KS,Park YJ,Park JS,Park JH,Jeon BN,Kim CH,Jun Y,Hyun YM,Kim M,Lee SM,Park CS,Im SH,Jun CD
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2018
Epithelial TRAF6 drives IL-17-mediated psoriatic inflammation.
JCI insight
Matsumoto R,Dainichi T,Tsuchiya S,Nomura T,Kitoh A,Hayden MS,Ishii KJ,Tanaka M,Honda T,Egawa G,Otsuka A,Nakajima S,Sakurai K,Nakano Y,Kobayashi T,Sugimoto Y,Kabashima K
12-0801 was used in Flow cytometry/Cell sorting to examine whether specific epithelial signalling pathways are essential for the development of robust IL-17-mediated immune responses.
Thu Aug 09 00:00:00 EDT 2018
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Nature communications
Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y
12-0801 was used in Flow cytometry/Cell sorting to assess the efficacy of a personalised cancer vaccine for eliciting postsurgical tumour specific-immunity.
Wed Apr 18 00:00:00 EDT 2018
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
The Journal of experimental medicine
Lehmann CHK,Baranska A,Heidkamp GF,Heger L,Neubert K,Lühr JJ,Hoffmann A,Reimer KC,Brückner C,Beck S,Seeling M,Kießling M,Soulat D,Krug AB,Ravetch JV,Leusen JHW,Nimmerjahn F,Dudziak D
12-0801 was used in Flow cytometry/Cell sorting to suggest that targeting antigens to FcγRs on DCs may be a promising approach to raise immunogenic or tolerogenic T cell responses to antigens of choice.
Mon May 01 00:00:00 EDT 2017
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
12-0801 was used in Flow cytometry/Cell sorting to further explore the role of the tyrosine-based activation motif-containing adaptors DAP12 and FcεRI γ-chain in C-type lectin receptor responses.
Wed Nov 20 00:00:00 EST 2019
Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain.
Frontiers in molecular neuroscience
Raj D,Yin Z,Breur M,Doorduin J,Holtman IR,Olah M,Mantingh-Otter IJ,Van Dam D,De Deyn PP,den Dunnen W,Eggen BJL,Amor S,Boddeke E
12-0801 was used in Flow cytometry/Cell sorting to indicate that microglia-induced neuroinflammation is predominant in the white matter of aging mice and humans as well as in EOAD brains.
Thu Oct 01 00:00:00 EDT 2020
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Journal of immunology (Baltimore, Md. : 1950)
Dolina JS,Cechova S,Rudy CK,Sung SJ,Tang WW,Lee J,Hahn YS,Le TH
12-0801 was used in Flow cytometry/Cell sorting to identify the functional role of collectrin in the liver.
Wed Mar 15 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model.
Scientific reports
Wang H,Mo L,Xiao X,An S,Liu X,Ba J,Wu W,Ran P,Yang P,Liu Z
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Feb 27 00:00:00 EST 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells.
Scientific reports
Wang H,Lin J,Zeng L,Ouyang C,Ran P,Yang P,Liu Z
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma.
Oncoimmunology
Hilmenyuk T,Ruckstuhl CA,Hayoz M,Berchtold C,Nuoffer JM,Solanki S,Keun HC,Beavis PA,Riether C,Ochsenbein AF
Tue Jan 12 00:00:00 EST 2021
Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4.
Frontiers in microbiology
Lai CY,Strange DP,Wong TAS,Lehrer AT,Verma S
12-0801 was used in Flow cytometry/Cell sorting to investigate the early immune response to purified Ebola virus glycoprotein alone in vitro and in vivo.
Tue Sep 29 00:00:00 EDT 2020
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
12-0801 was used in In vitro assays to identify a novel pathway of cross-talk between macrophages and dendritic cells.
Sat Oct 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Sun May 01 00:00:00 EDT 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
American journal of translational research
Wang H,Hu W,Liang Z,Zeng L,Li J,Yan H,Yang P,Liu Z,Wang L
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
CD80 and CD86 knockdown in dendritic cells regulates Th1/Th2 cytokine production in asthmatic mice.
Experimental and therapeutic medicine
Li JG,DU YM,Yan ZD,Yan J,Zhuansun YX,Chen R,Zhang W,Feng SL,Ran PX
12-0801 was used in Flow cytometry/Cell sorting to show how CD80 and CD86 knockdown in dendritic cells regulates Th1/Th2 cytokine production in asthmatic mice.
Tue Mar 01 00:00:00 EST 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
12-0801 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 EST 2016
B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.
Scientific reports
Bjarnadóttir K,Benkhoucha M,Merkler D,Weber MS,Payne NL,Bernard CCA,Molnarfi N,Lalive PH
12-0801-82 was used in Flow Cytometry to test the role for transforming growth factor-β1 expression in regulatory B cell function in autoimmune neuroinflammation.
Thu Oct 06 00:00:00 EDT 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
12-0801 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonist attenuate tumor growth via polarization of neutrophils toward an antitumor phenotype.
Oncoimmunology
Shrestha S,Noh JM,Kim SY,Ham HY,Kim YJ,Yun YJ,Kim MJ,Kwon MS,Song DK,Hong CW
12-0801 was used in Flow cytometry/Cell sorting to investigate how modulation of Ang II pathway attenuates tumour growth via polarisation of neutrophils to an antitumoural phenotype.
Tue Jan 12 00:00:00 EST 2021
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer.
Nature communications
Dubeykovskaya Z,Si Y,Chen X,Worthley DL,Renz BW,Urbanska AM,Hayakawa Y,Xu T,Westphalen CB,Dubeykovskiy A,Chen D,Friedman RA,Asfaha S,Nagar K,Tailor Y,Muthupalani S,Fox JG,Kitajewski J,Wang TC
12-0801 was used in Flow cytometry/Cell sorting to show that TFF2 is released by vagally modulated memory T cells to suppress the expansion of myeloid-derived suppressor cells through CXCR4.
Thu Feb 04 00:00:00 EST 2016
Activation of PPARγ by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization.
EBioMedicine
Feng X,Weng D,Zhou F,Owen YD,Qin H,Zhao J,Huang Y,Chen J,Fu H,Yang N,Chen D,Li J,Tan R,Shen P
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that PPARγ is bound and activated by apigenin with multiple knock-on effects culminating in M2 macrophage polarisation.
Fri Jul 01 00:00:00 EDT 2016
MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
The Journal of clinical investigation
Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B
12-0801 was used in Flow cytometry/Cell sorting to investigate the regulatory network of polarised activation of adipose tissue macrophages.
Mon Nov 02 00:00:00 EST 2015
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma.
mAbs
Overdijk MB,Verploegen S,Bögels M,van Egmond M,Lammerts van Bueren JJ,Mutis T,Groen RW,Breij E,Martens AC,Bleeker WK,Parren PW
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that phagocytosis is a fast, potent and clinically relevant mechanism of action that may contribute to the therapeutic activity of DARA in multiple myeloma and potentially other hematological tumors.
Mon Nov 30 00:00:00 EST 2015
A novel regulatory macrophage induced by a helminth molecule instructs IL-10 in CD4+ T cells and protects against mucosal inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Ziegler T,Rausch S,Steinfelder S,Klotz C,Hepworth MR,Kühl AA,Burda PC,Lucius R,Hartmann S
12-0801 was used in Flow cytometry/Cell sorting to investigate the mechanism by which the helminth immunomodulator AvCystatin induces a novel regulatory macrophage able to protect against allergic mucosal inflammation in mice.
Sun Feb 15 00:00:00 EST 2015
Haploinsufficiency for Stard7 is associated with enhanced allergic responses in lung and skin.
Journal of immunology (Baltimore, Md. : 1950)
Yang L,Lewkowich I,Apsley K,Fritz JM,Wills-Karp M,Weaver TE
12-0801 was used in Flow cytometry/Cell sorting to determine whether loss of Stard7 expression promotes allergic responses, showing that haploinsufficiency for Stard7 is associated with enhanced allergic responses.
Mon Jun 15 00:00:00 EDT 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses.
Toxicological sciences : an official journal of the Society of Toxicology
Marshall NB,Lukomska E,Long CM,Kashon ML,Sharpnack DD,Nayak AP,Anderson KL,Jean Meade B,Anderson SE
12-0801 was used in Flow cytometry/Cell sorting to examine the effects of dermal triclosan exposure on the skin and lymph nodes of mice and in a human skin model to identify mechanisms for augmenting allergic responses.
Tue Sep 01 00:00:00 EDT 2015
The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity.
Infection and immunity
Shourian M,Flaczyk A,Angers I,Mindt BC,Fritz JH,Qureshi ST
12-0801 was used in Flow cytometry/Cell sorting to show that Cryptococcus neoformans infected lungs showed a significantly higher number of neutrophils, exudate macrophages, CD11b(+) dendritic cells, and CD4(+) cells in B6.CBA-Cnes2 than in C57BL/6 mice.
Tue Dec 01 00:00:00 EST 2015
ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.
Cell reports
Zandi S,Nakao S,Chun KH,Fiorina P,Sun D,Arita R,Zhao M,Kim E,Schueller O,Campbell S,Taher M,Melhorn MI,Schering A,Gatti F,Tezza S,Xie F,Vergani A,Yoshida S,Ishikawa K,Yamaguchi M,Sasaki F,Schmidt-Ullrich R,Hata Y,Enaida H,Yuzawa M,Yokomizo T,Kim YB,Sweetnam P,Ishibashi T,Hafezi-Moghadam A
Tue Feb 24 00:00:00 EST 2015
Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development.
Scientific reports
Frodermann V,van Duijn J,van Pel M,van Santbrink PJ,Bot I,Kuiper J,de Jager SC
12-0801 was used in Flow cytometry/Cell sorting to study how MSC treatment affects not only inflammatory responses but also significantly reduces dyslipidaemia in mice.
Thu Oct 22 00:00:00 EDT 2015
Bifidobacterium longum CCM 7952 Promotes Epithelial Barrier Function and Prevents Acute DSS-Induced Colitis in Strictly Strain-Specific Manner.
PloS one
Srutkova D,Schwarzer M,Hudcovic T,Zakostelska Z,Drab V,Spanova A,Rittich B,Kozakova H,Schabussova I
12-0801 was used in Flow cytometry/Cell sorting to compare two Bifidobacterium longum ssp. longum strains for their capacity to prevent experimental colitis.
Tue May 03 00:00:00 EDT 2016
4T1 Murine Mammary Carcinoma Cells Enhance Macrophage-Mediated Innate Inflammatory Responses.
PloS one
Madera L,Greenshields A,Coombs MR,Hoskin DW
12-0801 was used in Flow cytometry/Cell sorting to investigate how cancers affect macrophage-dependent innate host defence, showing that they enhance macrophage-mediated innate inflammatory responses.
Tue May 03 00:00:00 EDT 2016
Loss of Gadkin Affects Dendritic Cell Migration In Vitro.
PloS one
Schachtner H,Weimershaus M,Stache V,Plewa N,Legler DF,Höpken UE,Maritzen T
12-0801 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which Gadkin and ARP2/3 regulate dendritic cell motility and migration.
Mon Jun 20 00:00:00 EDT 2016
Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus.
Nature communications
Yanagihara T,Sanematsu F,Sato T,Uruno T,Duan X,Tomino T,Harada Y,Watanabe M,Wang Y,Tanaka Y,Nakanishi Y,Suyama M,Yoshinori F
12-0801 was used in Immunohistochemistry on frozen tissues to study the regulation of Aire expression in medullary thymic epithelial cells.
Wed Nov 04 00:00:00 EST 2015
The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.
Nature immunology
Agudo J,Ruzo A,Tung N,Salmon H,Leboeuf M,Hashimoto D,Becker C,Garrett-Sinha LA,Baccarini A,Merad M,Brown BD
12-0801 was used in Flow cytometry/Cell sorting to identify the miR-126-VEGFR2 axis as an important regulator of the innate response that operates through multiscale control of pDCs.
Wed Jan 01 00:00:00 EST 2014
The glycosylated Rv1860 protein of Mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
PLoS pathogens
Satchidanandam V,Kumar N,Jumani RS,Challu V,Elangovan S,Khan NA
12-0801 was used in Flow cytometry/Cell sorting to investigate the effect of BCG-TB1860 on both the adaptive and innate immune responses.
Sun Jun 01 00:00:00 EDT 2014
Recognition of Salmonella by Dectin-1 induces presentation of peptide antigen to type B T cells.
European journal of immunology
Jackson N,Compton E,Trowsdale J,Kelly AP
12-0801 was used in Flow cytometry/Cell sorting to show that interaction of Salmonella Typhimurium with bone marrow derived dendritic cells results in enhanced presentation of peptide Ag to type B T cells.
Tue Apr 01 00:00:00 EDT 2014
Paclitaxel-exposed ovarian cancer cells induce cancer‑specific CD4+ T cells after doxorubicin exposure through regulation of MyD88 expression.
International journal of oncology
Kim JE,Jang MJ,Jin DH,Chung YH,Choi BS,Park GB,Kim YS,Kim S,Hur DY,Hung CF,Kim D
12-0801 was used in Flow cytometry/Cell sorting to study induction of cancer-specific CD4+ T cells by paclitaxel-exposed ovarian cancer cells after doxorubicin exposure through regulation of MyD88 expression.
Thu May 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease.
Virology
Wolf AI,Strauman MC,Mozdzanowska K,Williams KL,Osborne LC,Shen H,Liu Q,Garlick D,Artis D,Hensley SE,Caton AJ,Weiser JN,Erikson J
12-0801-82 was used in Flow Cytometry to investigate severity of influenza virus response with respiratory microbe presence.
Fri Aug 01 00:00:00 EDT 2014
More efficient induction of antitumor T cell immunity by exosomes from CD40L gene-modified lung tumor cells.
Molecular medicine reports
Wang J,Wang L,Lin Z,Tao L,Chen M
12-0801 was used in Flow cytometry/Cell sorting to investigate more efficient methods for inducing anti-tumour T cell immunity against lung cancer.
Wed Jan 01 00:00:00 EST 2014
Lung dendritic cells undergo maturation and polarization towards a T helper type 2-stimulating phenotype in a mouse model of asthma: Role of nerve growth factor.
Experimental and therapeutic medicine
Qin Q,Wang Z,Pan P,Cao Z,Xia Q,Tan H,Hu C
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Sat Nov 01 00:00:00 EDT 2014
Synergic silencing of costimulatory molecules prevents cardiac allograft rejection.
Journal of translational medicine
Zhang X,Liu Y,Zhang G,Shi J,Zhang X,Zheng X,Jiang AT,Zhang ZX,Johnston N,Siu KS,Chen R,Lian D,Koos D,Quan D,Min WP
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that the simultaneous silencing of CD40 and CD80 prevents allograft rejection.
Thu May 22 00:00:00 EDT 2014
Calcitonin gene-related peptide regulates type IV hypersensitivity through dendritic cell functions.
PloS one
Mikami N,Sueda K,Ogitani Y,Otani I,Takatsuji M,Wada Y,Watanabe K,Yoshikawa R,Nishioka S,Hashimoto N,Miyagi Y,Fukada S,Yamamoto H,Tsujikawa K
12-0801 was used in Flow cytometry/Cell sorting to study how calcionin gene-related peptide (CGRP) affects dendritic cells in adaptive immunity, showing that CGRP suppresses Th1 cell differentiation via inhibition of IL-12 and down regulates the expression of chemokine receptor and its ligand.
Mon Sep 15 00:00:00 EDT 2014
Hemozoin induces hepatic inflammation in mice and is differentially associated with liver pathology depending on the Plasmodium strain.
PloS one
Deroost K,Lays N,Pham TT,Baci D,Van den Eynde K,Komuta M,Prato M,Roskams T,Schwarzer E,Opdenakker G,Van den Steen PE
12-0801 was used in Flow cytometry/Cell sorting to elucidate the contribution of hemozoin to hepatic injury in mouse malaria models.
Tue Jan 26 00:00:00 EST 2016
Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells.
Experimental & molecular medicine
Park SN,Noh KT,Jeong YI,Jung ID,Kang HK,Cha GS,Lee SJ,Seo JK,Kang DH,Hwang TH,Lee EK,Kwon B,Park YM
12-0801 was used in Flow cytometry/Cell sorting to evaluate the effectiveness of RG-II-stimulated BMDC vaccination on the induction of antitumor immunity, showing that it inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells.
Fri Feb 08 00:00:00 EST 2013
Inactivation of tumor-specific CD8⁺ CTLs by tumor-infiltrating tolerogenic dendritic cells.
Immunology and cell biology
Harimoto H,Shimizu M,Nakagawa Y,Nakatsuka K,Wakabayashi A,Sakamoto C,Takahashi H
12-0801 was used in Flow cytometry/Cell sorting to investigate cancer immunosurveillance failure caused by the inactivation of CD8+ cytotoxic T lymphocytes by tolerogenic dendritic cells.
Tue Oct 01 00:00:00 EDT 2013
Prolonged apoptotic cell accumulation in germinal centers of Mer-deficient mice causes elevated B cell and CD4+ Th cell responses leading to autoantibody production.
Journal of immunology (Baltimore, Md. : 1950)
Khan TN,Wong EB,Soni C,Rahman ZS
12-0801 was used in Flow cytometry/Cell sorting to study the effect of Mer receptor tyrosine kinase deficiency on the clearance of apoptotic cells.
Fri Feb 15 00:00:00 EST 2013
Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.
PloS one
Chen ZG,Zhang TT,Li HT,Chen FH,Zou XL,Ji JZ,Chen H
Published figure using CD80 (B7-1) monoclonal antibody (Product # 12-0801-82) in Flow Cytometry
Tue Aug 20 00:00:00 EDT 2013
Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice.
PloS one
Forghani P,Harris W,Giver CR,Mirshafiey A,Galipeau J,Waller EK
12-0801 was used in Flow cytometry/Cell sorting to determine the role of immature myeloid cells in regulating T-cell activation and proliferation in bone marrow.
Thu Jan 23 00:00:00 EST 2014
High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.
PLoS neglected tropical diseases
Aulner N,Danckaert A,Rouault-Hardoin E,Desrivot J,Helynck O,Commere PH,Munier-Lehmann H,Späth GF,Shorte SL,Milon G,Prina E
12-0801 was used in Flow cytometry/Cell sorting to develop a novel phenotypic screening assay using virulent Leishmania amastigotes growing inside primary macrophage to identify new chemical entities with bona fide drug potential.
Thu Nov 14 00:00:00 EST 2013
Trogocytosis of CD80 and CD86 by induced regulatory T cells.
Cellular & molecular immunology
Gu P,Gao JF,D'Souza CA,Kowalczyk A,Chou KY,Zhang L
12-0801 was used in Flow cytometry/Cell sorting to provide a novel understanding of the interaction between iTregs and DCs, and its role in iTreg-mediated immune suppression.
Thu Mar 01 00:00:00 EST 2012
Trogocytosis of CD80 and CD86 by induced regulatory T cells.
Cellular & molecular immunology
Gu P,Gao JF,D'Souza CA,Kowalczyk A,Chou KY,Zhang L
12-0801 was used in Flow cytometry/Cell sorting to provide a novel understanding of the interaction between iTregs and DCs, and its role in iTreg-mediated immune suppression.
Thu Mar 01 00:00:00 EST 2012
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.
The Journal of experimental medicine
Yokosuka T,Takamatsu M,Kobayashi-Imanishi W,Hashimoto-Tane A,Azuma M,Saito T
12-0801 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms of PD-1-mediated suppression of T cell activation, showing that it inhibits T cell receptor signalling via SHP2.
Mon Jun 04 00:00:00 EDT 2012
ORFV: a novel oncolytic and immune stimulating parapoxvirus therapeutic.
Molecular therapy : the journal of the American Society of Gene Therapy
Rintoul JL,Lemay CG,Tai LH,Stanford MM,Falls TJ,de Souza CT,Bridle BW,Daneshmand M,Ohashi PS,Wan Y,Lichty BD,Mercer AA,Auer RC,Atkins HL,Bell JC
12-0801 was used in Flow cytometry/Cell sorting to investigate the use of Parapoxvirus ovis for the treatment of cancer.
Fri Jun 01 00:00:00 EDT 2012
Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirus.
Oncology reports
Gong HX,He L,Li XP,Wang YD,Li Y,Huang JJ,Wang Z,Xie D,Kung HF,Peng Y
12-0801 was used in Flow cytometry/Cell sorting to suggest that hTERTC27 gene-transduced dendritic cells can efficiently enhance immunity against gliomas in vitro and in vivo.
Sun Apr 01 00:00:00 EDT 2012
Nocardia brasiliensis cell wall lipids modulate macrophage and dendritic responses that favor development of experimental actinomycetoma in BALB/c mice.
Infection and immunity
Trevino-Villarreal JH,Vera-Cabrera L,Valero-Guillén PL,Salinas-Carmona MC
12-0801 was used in Flow cytometry/Cell sorting to investigate the parthenogenesis of Nocardia brasiliensis infection, showing that N.brasiliensis cell wall lipids modulate macrophage and dendritic responses, leading to actinomycetoma.
Mon Oct 01 00:00:00 EDT 2012
Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice.
PloS one
Kamphuis T,Meijerhof T,Stegmann T,Lederhofer J,Wilschut J,de Haan A
12-0801 was used in Flow cytometry/Cell sorting to assess the efficacy of a novel respiratory syncytial virus vaccine in mice.
Wed Sep 19 00:00:00 EDT 2012
SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells.
PloS one
Wang Z,Sokolovska A,Seymour R,Sundberg JP,Hogenesch H
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that loss of the Sharpin gene in mice significantly affects the immune function of dendritic cells.
Tue Jul 31 00:00:00 EDT 2012
Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants.
The Journal of experimental medicine
Purtha WE,Tedder TF,Johnson S,Bhattacharya D,Diamond MS
12-0801 was used in Flow cytometry/Cell sorting to study the ability of memory B cells to target mutant viral epitopes.
Mon Dec 19 00:00:00 EST 2011
Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.
Immunology
Buhtoiarov IN,Sondel PM,Wigginton JM,Buhtoiarova TN,Yanke EM,Mahvi DA,Rakhmilevich AL
12-0801 was used in Flow cytometry/Cell sorting to show that chemotherapy and anti-CD40 + CpG-ODN IT synergise in the induction of anti-tumour effects which are associated with the phenotypic repolarisation of tumour-associated Mφ.
Tue Feb 01 00:00:00 EST 2011
Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells.
Journal of immunology (Baltimore, Md. : 1950)
Lochner M,Bérard M,Sawa S,Hauer S,Gaboriau-Routhiau V,Fernandez TD,Snel J,Bousso P,Cerf-Bensussan N,Eberl G
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that a complex microbiota and cognate antigen are required to generate a properly regulated set of Foxp3+RORγt+ T cells and Th17 cells.
Tue Feb 01 00:00:00 EST 2011
Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on dendritic cell and T cell functions.
Journal of immunology (Baltimore, Md. : 1950)
Mikami N,Matsushita H,Kato T,Kawasaki R,Sawazaki T,Kishimoto T,Ogitani Y,Watanabe K,Miyagi Y,Sueda K,Fukada S,Yamamoto H,Tsujikawa K
12-0801 was used in Flow cytometry/Cell sorting to study how calcitonin gene-related peptide effects dendritic and T cells, and regulation of inflammation.
Wed Jun 15 00:00:00 EDT 2011
Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages.
Journal of medical microbiology
Daim S,Kawamura I,Tsuchiya K,Hara H,Kurenuma T,Shen Y,Dewamitta SR,Sakai S,Nomura T,Qu H,Mitsuyama M
12-0801 was used in Flow cytometry/Cell sorting to suggest a potential role of PPE37 in interfering with the pro-inflammatory cytokine response of infected macrophages.
Sun May 01 00:00:00 EDT 2011
B cell depletion reduces the development of atherosclerosis in mice.
The Journal of experimental medicine
Ait-Oufella H,Herbin O,Bouaziz JD,Binder CJ,Uyttenhove C,Laurans L,Taleb S,Van Vré E,Esposito B,Vilar J,Sirvent J,Van Snick J,Tedgui A,Tedder TF,Mallat Z
12-0801 was used in Flow cytometry/Cell sorting to challenge the current paradigm that B cell activation plays an overall protective role in atherogenesis, and identify new antiatherogenic strategies based on B cell modulation.
Mon Aug 02 00:00:00 EDT 2010
T cell immunoglobulin- and mucin-domain-containing molecule-4 attenuates concanavalin A-induced hepatitis by regulating macrophage.
Journal of leukocyte biology
Xu L,Qi J,Zhao P,Liang X,Ju Y,Liu P,Liu B,Guo C,Zhang L,Ma C,Gao L
12-0801 was used in Flow cytometry/Cell sorting to study how Tim-4 plays an important role in alleviating liver damage through inhibition of macrophage activity.
Sun Aug 01 00:00:00 EDT 2010
Dendritic cells continue to capture and present antigens after maturation in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Trombetta ES
12-0801 was used in Flow cytometry/Cell sorting to study the dynamics of Ag capture and presentation in situ, showing that dendritic cells continue to capture and present antigens after maturation.
Sun Aug 15 00:00:00 EDT 2010
Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma.
Journal of immunology (Baltimore, Md. : 1950)
Anraku M,Tagawa T,Wu L,Yun Z,Keshavjee S,Zhang L,Johnston MR,de Perrot M
12-0801 was used in Flow cytometry/Cell sorting to evaluate the potential of a combined Treg blockade-permetrexed anti-tumour treatment.
Thu Jul 15 00:00:00 EDT 2010
Foxa2 programs Th2 cell-mediated innate immunity in the developing lung.
Journal of immunology (Baltimore, Md. : 1950)
Chen G,Wan H,Luo F,Zhang L,Xu Y,Lewkowich I,Wills-Karp M,Whitsett JA
12-0801 was used in Flow cytometry/Cell sorting to demonstrate that selective expression of Foxa2 plays a key role in regulating Th2 cell-mediated pulmonary inflammation.
Tue Jun 01 00:00:00 EDT 2010
Group V secretory phospholipase A2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function.
Journal of immunology (Baltimore, Md. : 1950)
Giannattasio G,Fujioka D,Xing W,Katz HR,Boyce JA,Balestrieri B
12-0801 was used in Flow cytometry/Cell sorting to demonstrate the role of group V secretory phospholipase A(2) in antigen presenting cells following infection with the house dust mite, Dermatophagoides farinae.
Fri Oct 01 00:00:00 EDT 2010
Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.
Journal of immunology (Baltimore, Md. : 1950)
Larson RP,Zimmerli SC,Comeau MR,Itano A,Omori M,Iseki M,Hauser C,Ziegler SF
12-0801 was used in Flow cytometry/Cell sorting to demonstrate a role for TSLP in a Th2 model of contact hypersensitivity in mice.
Mon Mar 15 00:00:00 EDT 2010
Inhibition of B-cell activation by retinal pigment epithelium.
Investigative ophthalmology & visual science
Sugita S,Horie S,Yamada Y,Mochizuki M
12-0801 was used in Flow cytometry/Cell sorting to determine whether retinal pigment epithelial (RPE) cells can inhibit B-cell activation in vitro, showing that B-cell proliferation was suppressed.
Mon Nov 01 00:00:00 EDT 2010
Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70.
Journal of immunology (Baltimore, Md. : 1950)
Zietara N,Łyszkiewicz M,Gekara N,Puchałka J,Dos Santos VA,Hunt CR,Pandita TK,Lienenklaus S,Weiss S
12-0801 was used in Flow cytometry/Cell sorting to investigate the role of low level production of IFN, showing that its absence impairs antigen presentation capacity of splenic dendritic cells.
Wed Jul 15 00:00:00 EDT 2009
Transcriptional IL-15-directed in vivo DC targeting DNA vaccine.
Gene therapy
Tian S,Liu Z,Donahue C,Noh HS,Falo LD,You Z
12-0801 was used in Flow cytometry/Cell sorting to investigate next generation DNA vaccines against cancers and infectious diseases in both healthy and CD4 deficient individuals.
Thu Oct 01 00:00:00 EDT 2009
Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice.
Infection and immunity
Vargas-Inchaustegui DA,Tai W,Xin L,Hogg AE,Corry DB,Soong L
12-0801 was used in Flow cytometry/Cell sorting to investigate whether TLRs are involved in L. braziliensis-mediated dendritic cell activation, showing distinct roles for MyD88 and TLR2 in infection.
Wed Jul 01 00:00:00 EDT 2009
Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
The Journal of biological chemistry
Turner JD,Langley RS,Johnston KL,Gentil K,Ford L,Wu B,Graham M,Sharpley F,Slatko B,Pearlman E,Taylor MJ
12-0801 was used in Flow cytometry/Cell sorting to investigate the role of Wolbachia lipoprotein in pathogenesis of filariasis, showing that it stimulates innate and adaptive immunity through Toll-like receptors 2 and 6.
Fri Aug 14 00:00:00 EDT 2009
Dynamics of lung macrophage activation in response to helminth infection.
Journal of leukocyte biology
Siracusa MC,Reece JJ,Urban JF,Scott AL
Mon Dec 01 00:00:00 EST 2008
Leishmania braziliensis infection induces dendritic cell activation, ISG15 transcription, and the generation of protective immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Vargas-Inchaustegui DA,Xin L,Soong L
12-0801 was used in Flow cytometry/Cell sorting to investigate whether Leishmania braziliensis infection efficiently triggers innate responses in dendritic cells and the subsequent adaptive immune responses for parasite clearance.
Sun Jun 01 00:00:00 EDT 2008
Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes.
Molecular immunology
Xin L,Li K,Soong L
12-0801 was used in Flow cytometry/Cell sorting to suggest that La parasites, especially in their intracellular forms, have evolved unique strategies to actively down-regulate early innate signalling events.
Tue Jul 01 00:00:00 EDT 2008
Chimeric NK-receptor-bearing T cells mediate antitumor immunotherapy.
Blood
Zhang T,Lemoi BA,Sentman CL
12-0801 was used in Flow cytometry/Cell sorting to determine whether chimeric natural killer-receptor-bearing T cells can directly kill tumour cells and induce host immunity against tumours.
Thu Sep 01 00:00:00 EDT 2005
