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CD82 Antibody (PA5-13228) in IHC (P)
Immunohistochemistry analysis of CD82 in formalin-fixed and paraffin-embedded human lymph. Samples were incubated with CD82 polyclonal antibody (Product # PA5-13228) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Details
PA5-13228
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human CD82 (ST6)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2244577
Target Information
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C33 antigen; CD82; CD82 antigen; IA4; Inducible membrane protein R2; kangai 1 (suppression of tumorigenicity 6, prostate); kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); Metastasis suppressor Kangai-1; Metastasis suppressor Kangai-1 homolog; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27
Gene Aliases: 4F9; AA682076; AL023070; C33; CD82; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27
UniProt ID: (Human) P27701, (Mouse) P40237
Entrez Gene ID: (Human) 3732, (Mouse) 12521
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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