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Product Details
12566-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CD84 Fusion Protein Ag3192 (23-328 aa encoded by BC020063)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DSEIFTVNG ILGESVTFPV NIQEPRQVKI IAWTSKTSVA YVTPGDSETA PVVTVTHRNY YERIHALGPN YNLVISDLRM EDAGDYKADI NTQADPYTTT KRYNLQIYRR LGKPKITQSL MASVNSTCNV TLTCSVEKEE KNVTYNWSPL GEEGNVLQIF QTPEDQELTY TCTAQNPVSN NSDSISARQL CADIAMGFRT HHTGLLSVLA MFFLLVLILS SVFLFRLFKR RQDAASKKTI YTYIMASRNT QPAESRIYDE ILQSKVLPSK EEPVNTVYSE VQFADKMGKA STQDSKPPGT SSYEIVI (23-328 aa encoded by BC020063)
Target Information
CD84 is expressed on mature B cells and on B cell lines, including pre B cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD84; CD84 antigen (leukocyte antigen); Cell surface antigen MAX.3; DKFZp781E2378; Hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; SLAM family member 5
Gene Aliases: A130013D22Rik; CD84; CDw84; hCD84; LY9B; mCD84; SLAMF5
UniProt ID: (Human) Q9UIB8, (Mouse) Q18PI6
Entrez Gene ID: (Human) 8832, (Mouse) 12523
adaptive immune response
defense response
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of granulocyte macrophage colony-stimulating factor production
negative regulation of interleukin-18 production
negative regulation of mast cell activation
negative regulation of mast cell degranulation
innate immune response
leukocyte migration
regulation of store-operated calcium entry
cell adhesion
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