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Product Details
H00008832-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CD84 (NP_003865.1, 1 a.a. approximately 328 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQHHLWILL LCLQTWPEAA GKDSEIFTVN GILGESVTFP VNIQEPRQVK IIAWTSKTSV AYVTPGDSET APVVTVTHRN YYERIHALGP NYNLVISDLR MEDAGDYKAD INTQADPYTT TKRYNLQIYR RLGKPKITQS LMASVNSTCN VTLTCSVEKE EKNVTYNWSP LGEEGNVLQI FQTPEDQELT YTCTAQNPVS NNSDSISARQ LCADIAMGFR THHTGLLSVL AMFFLLVLIL SSVFLFRLFK RRQDAASKKT IYTYIMASRN TQPAESRIYD EILQSKVLPS KEEPVNTVYS EVQFADKMGK ASTQDSKPPG TSSYEIVI
Target Information
CD84 is expressed on mature B cells and on B cell lines, including pre B cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD84; CD84 antigen (leukocyte antigen); Cell surface antigen MAX.3; DKFZp781E2378; Hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; SLAM family member 5
Gene Aliases: CD84; hCD84; LY9B; mCD84; SLAMF5
UniProt ID: (Human) Q9UIB8
Entrez Gene ID: (Human) 8832
adaptive immune response
defense response
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of granulocyte macrophage colony-stimulating factor production
negative regulation of interleukin-18 production
negative regulation of mast cell activation
negative regulation of mast cell degranulation
innate immune response
leukocyte migration
regulation of store-operated calcium entry
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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