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Product Details
MA5-16860
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Camelid,
Horse,
Cat,
Ferret,
Human,
Mink,
Pig,
Rabbit,
Rhesus monkey
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
MM2/57
Immunogen
Human platelet membrane
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Purification
Protein A
Storage buffer
PBS with 1% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538339
Product Specific Information
Predicted to react with mustelid based on sequence homology.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5H9; 5H9 antigen; antigen CD9; BA-2/p24 antigen; BA2; CD9; CD9 antigen; CD9 antigen (p24); Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; mamu-MICA/B; MHC class I polypeptide-related sequence 3; MHC class I-related chain; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin-29; Tetraspanin29; Tspan-29
Gene Aliases: BTCC-1; CD9; DRAP-27; GIG2; Mamu-MIC1; MIC3; MRP-1; TSPAN-29; TSPAN29
UniProt ID: (Pig) Q8WMQ3, (Human) P21926, (Bovine) P30932, (Cat) P40239
cell adhesion
single fertilization
fusion of sperm to egg plasma membrane
myoblast fusion involved in skeletal muscle regeneration
paranodal junction assembly
receptor internalization
sperm-egg recognition
negative regulation of cellular component movement
cellular response to low-density lipoprotein particle stimulus
negative regulation of platelet aggregation
platelet degranulation
movement of cell or subcellular component
cell surface receptor signaling pathway
brain development
negative regulation of cell proliferation
response to water deprivation
oligodendrocyte development
platelet activation
glial cell migration
regulation of macrophage migration
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