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MA5-15817 targets CD94 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples.
The MA5-15817 immunogen is purified recombinant fragment of human CD94 expressed in E. Coli.
MA5-15817 detects CD94 which has a predicted molecular weight of approximately 21kDa.
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD94; CD94 antigen; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KP43; natural killer cell receptor; Natural killer cells antigen CD94; NK cell receptor
Gene Aliases: CD94; KLRD1
UniProt ID: (Human) Q13241
Entrez Gene ID: (Human) 3824
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