Proteintech

CD98 Polyclonal Antibody

CD98 Antibody in Immunocytochemistry (ICC/IF)

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CD98 Antibody (15193-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using SLC3A2 antibody 15193-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

CD98 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

15193-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:20,000

View 20 publications 20 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:2500-1:10,000

Immunocytochemistry (ICC/IF)

1:10-1:100

View 6 publications 6 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CD98/SLC3A2 Fusion Protein Ag7280 (269-630 aa encoded by BC001061)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: KDDVAQTDL LQIDPNFGSK EDFDSLLQSA KKKSIRVILD LTPNYRGENS WFSTQVDTVA TKVKDALEFW LQAGVDGFQV RDIENLKDAS SFLAEWQNIT KGFSEDRLLI AGTNSSDLQQ ILSLLESNKD LLLTSSYLSD SGSTGEHTKS LVTQYLNATG NRWCSWSLSQ ARLLTSFLPA QLLRLYQLML FTLPGTPVFS YGDEIGLDAA ALPGQPMEAP VMLWDESSFP DIPGAVSANM TVKGQSEDPG SLLSLFRRLS DQRSKERSLL HGDFHAFSAG PGLFSYIRHW DQNERFLVVL NFGDVGLSAG LQASDLPASA SLPAKADLLL STQPGREEGS PLELERLKLE PHEGLLLRFP YAA (269-630 aa encoded by BC001061)

Target Information

CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Anti-proliferation and anti-migration effects of Yishen Tongbi decoction in experimental rheumatoid arthritis by suppressing SLC3A2/integrin β3 signaling pathways.

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Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.

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Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.

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Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.

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