Invitrogen

CDC42 Recombinant Superclonal Antibody (8H7L24)

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (16) CDC42 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

712445

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Superclonal

Type

Antibody

Clone

8H7L24

Immunogen

Peptide corresponding to human CDC42 [aa25-aa36]
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2810207

Product Specific Information

This antibody is predicted to react with Pig, Mouse, Bovine.

Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Target Information

Rac1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for the Rac1 gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cell division control protein 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; RP1-224A6.5; small GTP binding protein CDC42

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Gene Aliases: CDC42; CDC42Hs; G25K; TKS

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UniProt ID: (Human) P60953

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Entrez Gene ID: (Human) 998

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Function(s)
GTPase activity protein binding GTP binding protein kinase binding GTP-dependent protein binding mitogen-activated protein kinase kinase kinase binding thioesterase binding apolipoprotein A-I receptor binding identical protein binding Rho GDP-dissociation inhibitor binding ubiquitin protein ligase activity small GTPase
Process(es)
sprouting angiogenesis cardiac conduction system development keratinocyte development Golgi organization regulation of mitotic nuclear division nuclear migration establishment or maintenance of cell polarity small GTPase mediated signal transduction blood coagulation positive regulation of gene expression negative regulation of gene expression protein ubiquitination substantia nigra development actin cytoskeleton organization macrophage differentiation positive regulation of cell growth hair follicle morphogenesis positive regulation of pseudopodium assembly T cell costimulation negative regulation of protein complex assembly keratinization regulation of protein stability positive regulation of cytokinesis positive regulation of peptidyl-serine phosphorylation adherens junction organization cellular protein localization establishment or maintenance of apical/basal cell polarity multicellular organism growth dendritic cell migration Fc-gamma receptor signaling pathway involved in phagocytosis negative regulation of epidermal growth factor receptor signaling pathway regulation of protein catabolic process regulation of protein heterodimerization activity positive regulation of neuron apoptotic process positive regulation of phosphatidylinositol 3-kinase activity positive regulation of DNA replication regulation of protein kinase activity positive regulation of JNK cascade filopodium assembly vascular endothelial growth factor receptor signaling pathway ephrin receptor signaling pathway neuron fate determination actin filament bundle assembly regulation of small GTPase mediated signal transduction positive regulation of muscle cell differentiation regulation of filopodium assembly establishment of Golgi localization positive regulation of synapse structural plasticity regulation of attachment of spindle microtubules to kinetochore heart contraction canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway positive regulation of epithelial cell proliferation involved in lung morphogenesis submandibular salivary gland formation epithelial-mesenchymal cell signaling hair follicle placode formation positive regulation of hair follicle cell proliferation organelle transport along microtubule actin filament branching epithelial cell-cell adhesion positive regulation of intracellular protein transport positive regulation of substrate adhesion-dependent cell spreading
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