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Product Details
PA5-18492
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (EQLSPGGQRRNLCE) corresponding to the internal amino acids of CDX2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10978762
Product Specific Information
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
Gene Aliases: CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626
Entrez Gene ID: (Human) 1045
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
trophectodermal cell differentiation
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
endosome to lysosome transport
organ morphogenesis
anterior/posterior axis specification
regulation of somitogenesis
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
labyrinthine layer development
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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