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This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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Protein Aliases: Carcinoembryonic antigen CGM1; Carcinoembryonic antigen gene family (CGM1); carcinoembryonic antigen gene family 4; carcinoembryonic antigen gene family member 1; Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein); Carcinoembryonic antigen-related cell adhesion molecule 3; CD66d; CD66d antigen; ceacam3 {ECO:0000312|RGD:2333}; nonspecific cross-reacting antigen
Gene Aliases: CD66D; CEA; CEACAM3; Ceacam5; Cear; CGM1; Cgm4; CGM4AA; RATCEAA; RATCGM4AA; W264; W282
UniProt ID: (Human) P40198
Entrez Gene ID: (Human) 1084, (Rat) 24926
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