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Product Details
15384-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CEL Fusion Protein Ag5262 (371-722 aa encoded by BC042510)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SEFTITKGL RGAKTTFDVY TESWAQDPSQ ENKKKTVVDF ETDVLFLVPT EIALAQHRAN AKSAKTYAYL FSHPSRMPVY PKWVGADHAD DIQYVFGKPF ATPTGYRPQD RTVSKAMIAY WTNFAKTGDP NMGDSAVPTH WEPYTTENSG YLEITKKMGS SSMKRSLRTN FLRYWTLTYL ALPTVTDQEA TPVPPTGDSE ATPVPPTGDS ETAPVPPTGD SGAPPVPPTG DSGAPPVPPT GDSGAPPVPP TGDSGAPPVP PTGDSGAPPV PPTGDAGPPP VPPTGDSGAP PVPPTGDSGA PPVTPTGDSE TAPVPPTGDS GAPPVPPTGD SEAAPVPPTD DSKEAQMPAV IRF (371-722 aa encoded by BC042510)
Target Information
Caboxyl Ester Lipase (CEL), also known as Bile Salt-Activated Lipase, catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. It also has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BAL; Bile salt-activated lipase; bile salt-dependent lipase, oncofetal isoform; Bile salt-stimulated lipase; BSSL; bucelipase; carboxyl ester hydrolase; Carboxyl ester lipase; carboxyl ester lipase (bile salt-stimulated lipase); Cholesterol esterase; fetoacinar pancreatic protein; lysophospholipase, pancreatic; Pancreatic lysophospholipase; Sterol esterase
Gene Aliases: 1810036E18Rik; BAL; BSDL; BSSL; CEase; Cel; CELL; FAP; FAPP; Lip1; LIPA; MODY8
UniProt ID: (Mouse) Q64285
Entrez Gene ID: (Human) 1056, (Mouse) 12613, (Rat) 24254
catalytic activity
sterol esterase activity
triglyceride lipase activity
receptor activity
protein binding
heparin binding
hydrolase activity
neurexin family protein binding
acylglycerol lipase activity
carboxylic ester hydrolase activity
lysophospholipase activity
protein complex binding
glycosphingolipid binding
retinyl-palmitate esterase activity
cell adhesion molecule
lipid metabolic process
triglyceride metabolic process
cholesterol catabolic process
neuron cell-cell adhesion
synapse assembly
fatty acid catabolic process
protein esterification
pancreatic juice secretion
intestinal cholesterol absorption
lipid digestion
intestinal lipid catabolic process
modulation of synaptic transmission
lipid catabolic process
retinol metabolic process
ceramide catabolic process
biological_process
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