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FIGURE: 1 / 2
CES1 Antibody (H00001066-B01P) in WB
Western Blot analysis of CES1 expression in transfected 293T cell line (H00001066-T01) by CES1 MaxPab polyclonal antibody.
Lane 1: CES1 transfected lysate(62.26 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CES1 transfected lysate(62.26 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00001066-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CES1 (AAH12418.1, 1 a.a. approximately 566 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MWLPALVLAT LAASAAWGHP SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA TSYPPMCTQD PKAGQLLSEL FTNRKENIPL KLSEDCLYLN IYTPADLTKK NRLPVMVWIH GGGLMVGAAS TYDGLALAAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW VQDNIASFGG NPGSVTIFGE SAGGESVSVL VLSPLAKNLF HRAISESGVA LTSVLVKKGD VKPLAEQIAI TAGCKTTTSA VMVHCLRQKT EEELLETTLK MKFLSLDLQG DPRESQPLLG TVIDGMLLLK TPEELQAERN FHTVPYMVGI NKQEFGWLIP MLMSYPLSEG QLDQKTAMSL LWKSYPLVCI AKELIPEATE KYLGGTDDTV KKKDLFLDLI ADVMFGVPSV IVARNHRDAG APTYMYEFQY RPSFSSDMKP KTVIGDHGDE LFSVFGAPFL KEGASEEEIR LSKMVMKFWA NFARNGNPNG EGLPHWPEYN QKEGYLQIGA NTQAAQKLKD KEVAFWTNLF AKKAVEKPPQ TEHIEL
Target Information
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACAT; acyl coenzyme A:cholesterol acyltransferase; Acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; Carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 2 (liver); CE-1; CEH; Cholesteryl ester hydrolase; Cocaine carboxylesterase; Egasyn; HMSE; human monocyte/macrophage serine esterase 1; Liver carboxylesterase 1; Methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; REH; Retinyl ester hydrolase; Serine esterase 1; TGH; triacylglycero; Triacylglycerol hydrolase
Gene Aliases: ACAT; CE-1; CEH; CES1; CES2; hCE-1; HMSE; HMSE1; PCE-1; REH; SES1; TGH
UniProt ID: (Human) P23141
Entrez Gene ID: (Human) 1066
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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