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Product Details
17192-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CFP Fusion Protein Ag9798 (120-469 aa encoded by BC015756)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LEWQLQACE DQQCCPEMGG WSGWGPWEPC SVTCSKGTRT RRRACNHPAP KCGGHCPGQA QESEACDTQQ VCPTHGAWAT WGPWTPCSAS CHGGPHEPKE TRSRKCSAPE PSQKPPGKPC PGLAYEQRRC TGLPPCPVAG GWGPWGPVSP CPVTCGLGQT MEQRTCNHPV PQHGGPFCAG DATRTHICNT AVPCPVDGEW DSWGEWSPCI RRNMKSISCQ EIPGQQSRGR TCRGRKFDGH RCAGQQQDIR HCYSIQHCPL KGSWSEWSTW GLCMPPCGPN PTRARQRLCT PLLPKYPPTV SMVEGQGEKN VTFWGRPLPR CEELQGQKLV VEEKRPCLHV PACKDPEEEE L (120-469 aa encoded by BC015756)
Target Information
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Bf; C3 Proaccelerator; cfb; Complement factor P; H2-Bf; Properdin; properdin P factor, complement
Gene Aliases: BFD; CFP; PFC; PFD; PROPERDIN
UniProt ID: (Human) P27918
Entrez Gene ID: (Human) 5199
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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