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Product Details
24418-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHAT Fusion Protein Ag19550 (399-748 aa encoded by BC130617)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
CHAT is known to be present exclusively in the cytoplasm of cholinergic neurons and anti-CHAT antibody has been considered as the best marker for cholinergic neurons.
Immunogen sequence: SDTHRALQL LHGGGYSKNG ANRWYDKSLQ FVVGRDGTCG VVCEHSPFDG IVLVQCTEHL LKHMTQSSRK LIRADSVSEL PAPRRLRWKC SPEIQGHLAS SAEKLQRIVK NLDFIVYKFD NYGKTFIKKQ KCSPDAFIQV ALQLAFYRLH RRLVPTYESA SIRRFQEGRV DNIRSATPEA LAFVRAVTDH KAAVPASEKL LLLKDAIRAQ TAYTVMAITG MAIDNHLLAL RELARAMCKE LPEMFMDETY LMSNRFVLST SQVPTTTEMF CCYGPVVPNG YGACYNPQPE TILFCISSFH SCKETSSSKF AKAVEESLID MRDLCSLLPP TESKPLATKE KATRPSQGHQ P (399-748 aa encoded by BC130617)
Target Information
ChAT catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetyl CoA; acetyl CoA:choline O-acetyltransferase; CHOACTase; choline acetylase; choline acetyltransferase; Choline O-acetyltransferase
Gene Aliases: B230380D24Rik; CHAT; CHOACTASE; CMS1A; CMS1A2; CMS6
UniProt ID: (Human) P28329
Entrez Gene ID: (Human) 1103, (Rat) 290567, (Mouse) 12647
antral ovarian follicle growth
response to hypoxia
phosphatidylcholine biosynthetic process
neurotransmitter secretion
response to nutrient
memory
acetylcholine biosynthetic process
response to drug
response to ethanol
chemical synaptic transmission
neuromuscular synaptic transmission
muscle organ development
establishment of synaptic specificity at neuromuscular junction
rhythmic behavior
adult walking behavior
metabolic process
dendrite development
neuron differentiation
neurotransmitter biosynthetic process
rhythmic excitation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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