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The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent helicase CHD3; CHD-3; Chromodomain-helicase-DNA-binding protein 3; hZFH; MGC40857; Mi 2a; Mi-2 alpha; Mi-2 autoantigen 240 kDa protein; Mi2 ALPHA; Mi2-alpha; Prp9 1; Zinc finger helicase; zinc-finger helicase (Snf2-like)
Gene Aliases: 2600010P09Rik; AF020312; CHD3; Chd7; Mi-2a; Mi2-ALPHA; Prp7; Prp9-1; ZFH
UniProt ID: (Human) Q12873
Entrez Gene ID: (Human) 1107, (Mouse) 216848
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